Filling a noticeable gap in the market for a new text solely focused on Dementia with Lewy Bodies, this book discusses cutting-edge topics covering the condition from diagnosis to management, as well as what is known about the neurobiological changes involved. With huge progress having been made over the last decade in terms of the disorder

Distils the most valuable discoveries in dementia research into clear, insightful chapters written by international experts.

This volume covers the latest methods used in clinical neurochemistry laboratories for both clinical practice and research. Chapters in this book discuss topics such as techniques for cerebrospinal fluid (CSF) collection, pre-analytical processing, and basic CSF analysis; an examination of biomarkers including ELISA and automated immunochemical assays for amyloid and tau markers for Alzheimer’s disease; the analysis of neurofilaments by digital ELISA; and an example of successful novel immunoassay development. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and thorough, Cerebrospinal Fluid Biomarkers is a valuable resource for clinicians and researchers to use in CSF labs and CSF courses.

Dementia with Lewy bodies (DLB) is perhaps the second most common cause of degenerative dementia after Alzheimer's disease. This book, which represents the first authoritative statement about DLB, arises from a workshop held in Newcastle, England, in October 1995, which brought together leading investigators with clinical and research experience of this condition. It includes review articles, case studies and recent research findings from the main centres studying DLB. Covering the classification, cognitive manifestations, clinical diagnosis, epidemiology, genetics, neuropathology, neurochemistry and treatment of DLB, this is a landmark publication in clinical neuroscience. It presents new operational criteria for research on DLB, and will interest all concerned with the problem of dementia in the elderly.

Lewy body dementia (LBD) is a complex and challenging brain disorder. It is complex because it affects many parts of the brain in ways that scientists are trying to understand more fully. It is challenging because its many possible symptoms make it hard to do everyday tasks that once came easily. Although less known than its ?cousins? Alzheimer's disease and Parkinson's disease, LBD is not a rare disorder. More than 1 million Americans, most of them older adults, are affected by its disabling changes in the ability to think and move. As researchers seek better ways to treat LBD?and ultimately to find a cure?people with LBD and their families struggle to get an accurate diagnosis, find the best treatment, and manage at home.

Patients, spouses, families, and caregivers dealing with dementia face a host of complex issues, particularly when they must confront Dementia with Lewy Bodies or Parkinson's Disease. Until now there has been no guidebook for the general public to help navigate these challenging disorders. In Dementia with Lewy Bodies and Parkinson's Disease Dementia, Dr. J. Eric Ahlskog draws on 30 years of clinical and research work at Mayo Clinic to arm patients and families with crucial information that will enable them to work in tandem with their doctors. A diagnosis of dementia can be devastating, leaving families and caregivers struggling with a loved one's radically-impaired thinking and memory. When dementia is coupled with Parkinson's, which will develop in Parkinson's patients that live long enough, or with Lewy Bodies, which is the second leading cause of dementia behind Alzheimer's, the difficulties become even more daunting. And while these disorders are all too common, most people have little solid information about them. Too often doctors cannot spend the necessary time answering questions or discussing the specific challenges and treatments for these kinds of dementia during office visits. Arriving for a doctor appointment knowing the issues and treatment options beforehand gives patients and families an important head start. Dr. Ahlskog clearly explains all aspects of these disorders, their causes, symptoms, most effective drug treatments, proper doses, and which medications to avoid. He also discusses the complications that can arise in treating these conditions, given the variety of available medications and their possible side effects and interactions. While a cure does not yet exist, in this accessible, highly informative guidebook, Dr. Ahlskog shows that optimal medical treatment can markedly improve the quality of life for both patients and family.

This book describes biological and clinical aspects of dementia with Lewy bodies (DLB), one of the most common types of progressive dementia, although in most cases the cause is unknown. The editor has made a major contribution to the understanding of the disease since he first reported DLB in 1976. Written by renowned experts in the field, the book discusses not only diagnostic criteria and clinical symptoms of DLB but also various imaging modalities and biological markers such as alpha-synuclein, which are useful for diagnosis of DLB. Dementia with Lewy Bodies is aimed at psychiatrists, neurologists, and researchers who are interested in DLB.