This special issue entitled “Soft and hard tissue regeneration” will cover both periodontal and implant therapies. Regenerative periodontal treatment goal is to restore functional periodontal support offering a valuable treatment alternative even for teeth with large periodontal destruction, which may be successfully treated and maintained in health for long periods. In most cases where teeth are extracted for periodontal reasons, implant therapy will demand large bone augmentation procedures. Lack of sufficient bone volume may prevent placement of dental implants. In extreme cases, large bone reconstruction is indispensable before implant placement can be performed. Although, most bone grafts are only able to fill and maintain a space, where bone regeneration can occur (“osseoconductive”), the ideal bone graft will also promote osseous regeneration (“osseoinductive”). Several bone augmentation procedures have been described, each, presenting advantages and shortcomings. Success of bone augmentation procedures depends on the presence of bone forming cells, primary wound closure over the augmented area, space creation and maintenance where bone can grow and proper angiogenesis of the grafted area. Factors that influence the choice of the surgical technique are the estimated duration of surgical procedure, its complexity, cost, total estimated length of procedure until the final rehabilitations may be installed and the surgeons’ experience. This special issue will have a definite clinical orientation, and be entirely dedicated to soft and hard tissue regenerative treatment alternatives, both in periodontal and implant therapy, discussing their rationale, indications and clinical procedures. Internationally renowned leading researchers and clinicians will contribute with articles in their field of expertize.

Preface; Acknowledgments; Chapter 1: Beyond Osseointegration, Anatomy and Biology of Peri-implant Soft Tissues, Choosing Between a Submerged and Nonsubmerged Approach; Chapter 2: Systematic Evaluation of the Esthetic Implant Patient, A Simplified Approach to Patient Evaluation, Facial and Dental Symmetry, Periodontal Biotype, Anatomic Limitations, Marginal Tissue Recession, Classification of Alveolar Ridge Defects in Esthetic Implant Therapy; Chapter 3: Surgical Techniques for Management of Peri-implant Soft Tissues, Instrumentation for Soft Tissue Management in Implant Therapy, Criteria for Optimal Flap Design in Implant Therapy, Application of Plastic Surgery Principles in Implant Therapy, Flap Management Considerations, Surgical Maneuvers for Management of Peri-implant Soft Tissues, Flap Management Considerations for Mandibular Implant Surgery, Flap Management Considerations for Maxillary Implant Surgery, Flap Design and Management Considerations for Esthetic Implant Therapy; Chapter 4: The Bio-Col Technique, The Importance of Site Preservation, Bio-Col Technique for Delayed Implant Placement, Bio-Col Technique for Immediate Implant Placement, Long-Term Clinical Results Obtained with the Bio-Col Technique, Suggested Refinements, Summary; Chapter 5: Soft Tissue Grafting in Implant Therapy, Periodontal Plastic Surgery, Oral Soft Tissue Grafting with Dental Implants, Modified Palatal Roll Technique for Dental Implants, Epithelialized Palatal Graft Technique for Dental Implants, Subepithelial Connective Tissue Graft Technique for Dental Implants, Summary; Chapter 6: The Vascularized Interpositional Periosteal-Connective Tissue (VIP-CT) Flap, Rationale and Biologic Basis, General Considerations, Potential Complications, Surgical Procedure, Clinical Experience, Summary; Chapter 7: Esthetic Implant Therapy: A Comprehensive Approach, Philosophy of Care, Rationale for Site Preservation, Implant Site-Development Techniques, Prosthetic Considerations for Enhancing Outcomes in Implant Therapy, Surgical Considerations for Enhancing Outcomes in Implant Therapy, Use of Platelet-Rich Plasma to Enhance Outcomes in Implant Therapy, Conceptual Framework for Esthetic Implant Site Development, Appendix: Treatment Algorithms for Esthetic Implant Therapy, Index.

Tissue regeneration is a vast subject, with many different important aspects to consider. Regenerative medicine is a new branch of medicine that tries to change the course of chronic diseases and, in many cases, regenerates the organ systems that fail due to age, disease, damage, or genetic defects. The main purpose of this book is to point out the interest of some important topics of tissue regeneration and the progress in this field as well as the variety of different surgical fields and operations. This book includes 7 sections and 11 chapters that provide an overview of the essentials in tissue regeneration science and their potential applications in surgery. The authors of each chapter have given consolidated information on ground realities and attempted to provide a comprehensive knowledge of tissue engineering and regeneration. This book will be useful to researchers and students of biological and biomedical sciences (medical and veterinarian researchers).

Covering treatment planning to restoration, Principles and Practice of Single Implant Restorations is the first book specifically designed to train Endodontists and General Dentists for a single tooth implant and restorations. It describes surgical principles, implant placement, implant site preparation, bone grafts and bone substitute materials, tooth extraction, guided bone regeneration, immediate implant placement, surgical defects, and single-tooth esthetic considerations. Expert authors Dr. Mahmoud Torabinejad, Dr. Charles Goodacre, and Dr. Mohammed Sabeti provide detailed guidelines for the use of single tooth implants as an appropriate and compelling treatment tool. Single tooth implants have been established as a new tool by the AAE, allowing you to use single tooth implants as a part of overall treatment planning for patients with a tooth that must be extracted. Easy-to-follow content generally follows the diagnosis and treatment planning for a single tooth implant and restoration, describing how a clinician might actually perform a single tooth implant. Unique! Instructions designed exclusively for Endodontists and General Dentists doing endodontic work help you use single tooth implants to treat a diseased single tooth. Expert authors Torabinejad, Goodacre, and Sabeti are AAE leaders as well as instructors at Loma Linda University, one of the first schools to have a Master’s-level course in single-tooth implants, and have recruited contributors from top names in the endodontic and implant fields.

This new edition reflects the remarkable clinical and scientific advances in bone and soft tissue reconstruction since publication of the first edition of this award-winning book 7 years ago. Highly potent recombinant growth factors are now widely available, and numerous chapters describe and provide cases illustrating how to incorporate these protein therapeutics into clinical practice. The reader will find information about the basic principles of tissue engineering, use of growth factors in orthopedics, and potential applications of gene therapy in dentistry. The book also features chapters on periodontal regeneration and localized implant site development. A section on applications for craniofacial reconstruction describes procedures for use of growth factors in the treatment of defects. The final section addresses orthopedic indications for tissue engineering. An invaluable, up-to-date resource for practitioners wanting to integrate tissue engineering into their clinical practice, researchers seeking inspiration for new directions, and those new to this fascinating field.

Biomaterials for Oral and Dental Tissue Engineering examines the combined impact of materials, advanced techniques and applications of engineered oral tissues. With a strong focus on hard and soft intraoral tissues, the book looks at how biomaterials can be manipulated and engineered to create functional oral tissue for use in restorative dentistry, periodontics, endodontics and prosthodontics. Covering the current knowledge of material production, evaluation, challenges, applications and future trends, this book is a valuable resource for materials scientists and researchers in academia and industry. The first set of chapters reviews a wide range of biomaterial classes for oral tissue engineering. Further topics include material characterization, modification, biocompatibility and biotoxicity. Part Two reviews strategies for biomaterial scaffold design, while chapters in parts three and four review soft and hard tissues. Connects materials science with restorative dentistry Focuses on the unique field of intraoral tissues Highlights long-term biocompatibility and toxicity of biomaterials for engineered oral tissues