Nuclear Architecture and Dynamics provides a definitive resource for (bio)physicists and molecular and cellular biologists whose research involves an understanding of the organization of the genome and the mechanisms of its proper reading, maintenance, and replication by the cell. This book brings together the biochemical and physical characteristics of genome organization, providing a relevant framework in which to interpret the control of gene expression and cell differentiation. It includes work from a group of international experts, including biologists, physicists, mathematicians, and bioinformaticians who have come together for a comprehensive presentation of the current developments in the nuclear dynamics and architecture field. The book provides the uninitiated with an entry point to a highly dynamic, but complex issue, and the expert with an opportunity to have a fresh look at the viewpoints advocated by researchers from different disciplines. Highlights the link between the (bio)chemistry and the (bio)physics of chromatin Deciphers the complex interplay between numerous biochemical factors at task in the nucleus and the physical state of chromatin Provides a collective view of the field by a large, diverse group of authors with both physics and biology backgrounds

Spin Dynamics: Basics of Nuclear Magnetic Resonance, Second Edition is a comprehensive and modern introduction which focuses on those essential principles and concepts needed for a thorough understanding of the subject, rather than the practical aspects. The quantum theory of nuclear magnets is presented within a strong physical framework, supported by figures. The book assumes only a basic knowledge of complex numbers and matrices, and provides the reader with numerous worked examples and exercises to encourage understanding. With the explicit aim of carefully developing the subject from the beginning, the text starts with coverage of quarks and nucleons and progresses through to a detailed explanation of several important NMR experiments, including NMR imaging, COSY, NOESY and TROSY. Completely revised and updated, the Second Edition features new material on the properties and distributions of isotopes, chemical shift anisotropy and quadrupolar interactions, Pake patterns, spin echoes, slice selection in NMR imaging, and a complete new chapter on the NMR spectroscopy of quadrupolar nuclei. New appendices have been included on Euler angles, and coherence selection by field gradients. As in the first edition, all material is heavily supported by graphics, much of which is new to this edition. Written for undergraduates and postgraduate students taking a first course in NMR spectroscopy and for those needing an up-to-date account of the subject, this multi-disciplinary book will appeal to chemical, physical, material, life, medical, earth and environmental scientists. The detailed physical insights will also make the book of interest for experienced spectroscopists and NMR researchers. • An accessible and carefully written introduction, designed to help students to fully understand this complex and dynamic subject • Takes a multi-disciplinary approach, focusing on basic principles and concepts rather than the more practical aspects • Presents a strong pedagogical approach throughout, with emphasis placed on individual spins to aid understanding • Includes numerous worked examples, problems, further reading and additional notes Praise from the reviews of the First Edition: "This is an excellent book... that many teachers of NMR spectroscopy will cherish... It deserves to be a ‘classic’ among NMR spectroscopy texts." NMR IN BIOMEDICINE "I strongly recommend this book to everyone...it is probably the best modern comprehensive description of the subject." ANGEWANDTE CHEMIE, INTERNATIONAL EDITION

Stephen M. Meyer steps back from the emotions and rhetoric surrounding the nuclear arms debates to provide a systematic examination of the underlying determinants of nuclear weapons proliferation. Looking at current theories of nuclear proliferation, he asks: Must a nation that acquires the technical capability to manufacture nuclear weapons eventually do so? In an analysis, remarkable for its rigor and accessibility, Meyer provides the first empirical, statistical model explaining why particular countries became nuclear powers when they did. His findings clearly contradict the notion that the pace of nuclear proliferation is controlled by a technological imperative and show that political and military factors account for the past decisions of nations to acquire or forgo the development of nuclear weapons.

The dynamics of nuclear structures described in this book furnish the basis for a comprehensive understanding of how the higher-order organization and function of the nucleus is established and how it correlates with the expression of a variety of vital activities such as cell proliferation and differentiation. The resulting volume creates an invaluable source of reference for researchers in the field.

th This workshop was the 15 in a series that addresses the subject of the dynamics of nuclear reactions. These workshops are dedicated to the concept that bringing together scientists from diverse areas of nuclear reactions promotes the vibrant exchange of ideas. This workshop hosted presentations from experimentalists and theorists, intermediate energy to ultrarelativistic energies, and final results to recent speculations. Many of these scientists would not normally be exposed to the work done in other subfields. Thus the Winter Workshop on Nuclear Dynamics plays a unique role in information exchange and the stimulation of new ides. The field of nuclear dynamics has a bright future. New accelerators are being planned and completed around the world. New detectors are being constructed. New models and theories are being developed to describe these phenomena. The Winter Workshop on Nuclear Dynamics will continue to promote this lively and compelling field of research. WOLFGANG BAUER AND GARY D. WESTFALL v Previous Workshops The following table contains a list of the dates and locations of the previous Winter Workshops on Nuclear Dynamics as well as the members of the organizing committees. The chairpersons of the conferences are underlined.

th The 13 Winter Workshop on Nuclear Dynamics is the latest installment in a series of workshops that was started in 1978. This series has grown into a tradition, bringing together experimental and theoretical expertise from all areas of the study of nuclear dynamics. As always, the organizers had placed emphasis on the important aspect of cross fertilization between the different energy regimes and wa.ys of viewing a collision of energetic nuclei. This emphasis is reflected in the broad range of topics covered in these proceedings. Phase transitions in nuclear collisions received most of the attention during this workshop, as indicated by the number of contributions on this subject. Many of the questions in connection with these topics remain not settled and will have a huge impact on the physics that can be extracted from experiments at the future Relativistic Heavy Ion Collider. While the experimental program at the AGS is winding down, the NSCL upgrade and RHIC promise a bright future for our field in the USA. In Europe and Asia, major new facilities are under construction as well. The excitement and anticipation in connection with these new opportunities are reflected in these proceedings as well. Wolfgang Bauer Michigan State University Alice Mignerey University of Maryland v PREVIOUS WORKSHOPS The following table contains a list of the dates and locations of the previous Winter Workshops on Nuclear Dynamics as well as the members of the organizing committees. The chairpersons of the conferences are underlined.

The 12th Winter Workshop on Nuclear Dynamics carried on the tradition, started in 1978, of bringing together scientists working in all regimes of nuclear dynamics. This broad range of related topics allows the researcher attending the Workshop to be exposed to work that normally would be considered outside his/her field, but could po tentially add a new dimension to the understanding of his/her work. At Snowbird, we brought together experimentalists working with heavy ion beams from 10 MeV/nucleon up to 200 GeV /nucleon and theoretical physicists working in diverse areas ranging from antisymmetrized fermionic dynamics to perturbative quantum chromo dynamics. Fu ture work at RHIC was discussed also, with presentations from several of the experimen tal groups. In addition, several talks addressed issues of cross-disciplinary relevance, from the study of water-drop-collisions, to the multi-fragmentation of buckyballs. Clearly the field of nuclear dynamics has a bright future. The understanding of the nuclear equation of state in all of its manifestations is being expanded on all fronts both theoretically and experimentally. Future Workshops on Nuclear Dynamics will certainly have much progress to report. Gary D. Westfall Wolfgang Bauer Michigan State Universzty v PREVIOUS WORKSHOPS The following table contains a list of the dates and locations of the previous Winter Workshops on Nuclear Dynamics as well as the members of the organizing committees. The chairpersons of the conferences are underlined.