Explaining how nanotechnology works and looking at recent advances and the future of the field, this book offers a simple, brief, almost math-free introduction for nonscientists.

This chapter presents an overview of nanosensors and nanotechnology, including nanosensor construction, six basic types of nanosensors, and six prerequisites for the optimum functioning of nanosensors. The chapter discusses the transformation of nanomaterials when exposed to the environment, followed by safety issues involving human exposure and environmental pathways such as lung, dermal, and intestinal ingestion. Finally, nanosensor utilization in the homeland security and infrastructure industries was discussed, which include radiation physics, delayed neutron activation analysis, terahertz imaging, biosensing, and chemical vapors. New instrument standards and test methods and data are also discussed.

The projected economic and societal benefits of nanotechnology have propelled global investments by nations and companies. The United States launched the first national nanotechnology initiative in 2000. Since then, more than 60 nations have launched similar initiatives. In 2006, global public investment in nanotechnology was estimated to be $6.4 billion, with an additional $6.0 billion provided by the private sector. More than 600 nanotechnology products are now in the market, generally offering incremental improvements over existing products. However, proponents maintain that nanotechnology research and development currently underway could offer revolutionary applications with significant implications for the U.S. economy, national and homeland security, and societal well-being. These investments, coupled with nanotechnology's potential implications, have raised interest and concerns about the U.S. competitive position. The data used to assess competitiveness in mature technologies and industries, such as revenues and market share, are not available for assessing nanotechnology. In fact, the U.S. government does not currently collect such data for nanotechnology, nor is comparable international data available. Without this information, an authoritative assessment of the U.S. competitive position is not possible. Alternatively, indicators of U.S. scientific and technological strength (e.g., public and private research investments, nanotechnology papers published in scientific journals, patents) may provide insight into the current U.S. position and serve as bellwethers of future competitiveness. By these criteria, the United States appears to be the overall global leader in nanotechnology. However, other nations are investing heavily and may lead in specific areas of nanotechnology. Some believe the U.S. leadership position in nanotechnology may not be as large as it has been in previous emerging technologies. Efforts to develop and commercialise nanotechnology face a variety of challenges - e.g., technical hurdles; availability of capital; environmental, health, and safety concerns; and immature manufacturing technology and infrastructure. Some advocate a more active federal government role in overcoming these challenges, including funding to aid in the translation of research to commercial products; general and targeted tax provisions; incentives for capital formation; increased support for development of manufacturing and testing infrastructure, standards and nomenclature development, and education and training; creation of science, technology, and innovation parks; and efforts to establish a stable and predictable regulatory environment that keeps pace with innovation. Some support a more limited federal role. Some who hold this view maintain that the market, free from government interventions, is most efficient. They assert that federal efforts can create market distortions and result in the federal government picking "winners and losers" among technologies, companies, and industries. Others oppose federal support for industrial research and applications, labelling such efforts "corporate welfare." Still others argue for a moratorium on nanotechnology R&D until environmental, health, and safety concerns are addressed.

New and unpredicted technologies are emerging at an unprecedented pace around the world. Communication of those new discoveries is occurring faster than ever, meaning that the unique ownership of a piece of new technology is no longer a sufficient position, if not impossible. In today’s world, recognition of the potential applications of a technology and a sense of purpose in exploiting it are far more important than simply having access to it. Technological surprise has and will continue to take many forms. A plethora of new technologies are under development for peaceful means but may have un- tended security consequences and will certainly require innovative counterme- ures. A relevant example is the tremendous development in biotechnology that has occurred since the advent of recombinant DNA and tissue culture-based processes in the 1970s. If US government agencies and the defense and academic commu- ties had more clearly recognized the potential for biotechnology to affect fun- mental security and warfighting doctrines 20 years ago, the situation today could be very different. Defense against chemical and biological weapons – from both states and nonstate actors – currently presents a threat that is difficult to predict and for which traditional solutions are increasingly less effective. Nanotechnology has emerged as a well-funded discipline that, like biote- nology, carries the potential for groundbreaking applications and the potential for unpredictable harm. The world is likely 20 years away from the full impact of the nanotechnology on defensive capabilities.

Nanoscale science and technology, often referred to as "nanoscience" or "nanotechnology," are science and engineering enabled by our relatively new ability to manipulate and characterize matter at the level of single atoms and small groups of atoms. This capability is the result of many developments in the last two decades of the 20th century, including inventions of scientific instruments like the scanning tunneling microscope. Using such tools, scientists and engineers have begun controlling the structure and properties of materials and systems at the scale of 10?9 meters, or 1/100,000 the width of a human hair. Scientists and engineers anticipate that nanoscale work will enable the development of materials and systems with dramatic new properties relevant to virtually every sector of the economy, such as medicine, telecommunications, and computers, and to areas of national interest such as homeland security. Indeed, early products based on nanoscale technology have already found their way into the marketplace and into defense applications. In 1996, as the tremendous scientific and economic potential of nanoscale science and technology was beginning to be recognized, a federal interagency working group formed to consider creation of a national nanotechnology initiative (NNI). As a result of this effort, around $1 billion has been directed toward NNI research since the start of FY 2001. At the request of officials in the White House National Economic Council and agencies that are participating in NNI, the National Research Council (NRC) agreed to review the NNI. The Committee for the Review of the National Nanotechnology Initiative was formed by the NRC and asked to consider topics such as the current research portfolio of the NNI, the suitability of federal investments, and interagency coordination efforts in this area.

The National Nanotechnology Initiative (NNI) is a multiagency, multidisciplinary federal initiative comprising a collection of research programs and other activities funded by the participating agencies and linked by the vision of "a future in which the ability to understand and control matter at the nanoscale leads to a revolution in technology and industry that benefits society." As first stated in the 2004 NNI strategic plan, the participating agencies intend to make progress in realizing that vision by working toward four goals. Planning, coordination, and management of the NNI are carried out by the interagency Nanoscale Science, Engineering, and Technology (NSET) Subcommittee of the National Science and Technology Council (NSTC) Committee on Technology (CoT) with support from the National Nanotechnology Coordination Office (NNCO). Triennial Review of the National Nanotechnology Initiative is the latest National Research Council review of the NNI, an assessment called for by the 21st Century Nanotechnology Research and Development Act of 2003. The overall objective of the review is to make recommendations to the NSET Subcommittee and the NNCO that will improve the NNI's value for basic and applied research and for development of applications in nanotechnology that will provide economic, societal, and national security benefits to the United States. In its assessment, the committee found it important to understand in some detail-and to describe in its report-the NNI's structure and organization; how the NNI fits within the larger federal research enterprise, as well as how it can and should be organized for management purposes; and the initiative's various stakeholders and their roles with respect to research. Because technology transfer, one of the four NNI goals, is dependent on management and coordination, the committee chose to address the topic of technology transfer last, following its discussion of definitions of success and metrics for assessing progress toward achieving the four goals and management and coordination. Addressing its tasks in this order would, the committee hoped, better reflect the logic of its approach to review of the NNI. Triennial Review of the National Nanotechnology Initiative also provides concluding remarks in the last chapter.