Egg transfer was first performed in 1890, but for half a century it received scant attention. However, since 1950 the technique has become increasingly widely used - in the laboratory for fundamental studies and more recently in practice, both veterinary and medical, to boost reproductive potential of genetically superior cattle and to overcome sterility due to impaired rubal function in women. As a result, a considerable body of literature has accumulated, totaling well in excess of a thousand references. But till now there has not been a single comprehensive text devoted solely to this subject. The present work was designed to meet that need at a time when the field is fast expanding with new techniques and approaches constantly being evolved. One need only cite the tremendous rate of progress in human egg transfer in the last three years. The work embraces laboratory and farm animals and primates, including man, altogether representing a total of 16 species.

"Egg transfer was first performed in 1890, but for half a century it received scant attention. However, since 1950 the technique has become increasingly widely used - in the laboratory for fundamental studies and more recently in practice, both veterinary and medical, to boost reproductive potential of genetically superior cattle and to overcome sterility due to impaired rubal function in women. As a result, a considerable body of literature has accumulated, totaling well in excess of a thousand references. But till now there has not been a single comprehensive text devoted solely to this subject. The present work was designed to meet that need at a time when the field is fast expanding with new techniques and approaches constantly being evolved. One need only cite the tremendous rate of progress in human egg transfer in the last three years. The work embraces laboratory and farm animals and primates, including man, altogether representing a total of 16 species."--Provided by publisher.

"Egg transfer was first performed in 1890, but for half a century it received scant attention. However, since 1950 the technique has become increasingly widely used - in the laboratory for fundamental studies and more recently in practice, both veterinary and medical, to boost reproductive potential of genetically superior cattle and to overcome sterility due to impaired rubal function in women. As a result, a considerable body of literature has accumulated, totaling well in excess of a thousand references. But till now there has not been a single comprehensive text devoted solely to this subject. The present work was designed to meet that need at a time when the field is fast expanding with new techniques and approaches constantly being evolved. One need only cite the tremendous rate of progress in human egg transfer in the last three years. The work embraces laboratory and farm animals and primates, including man, altogether representing a total of 16 species."--Provided by publisher.

Developmental biology has been transformed recently by discoveries in the fields of molecular biology, cell biology, and immunology. New ways of manip ulating mammalian development are uncovering control mechanisms and ena bling us to apply them in solving practical problems in animal production and human health. This book outlines some of these new manipulations and how they have contributed to the present state of developmental biology. Chapter 1 describes gene transfer by micro injection of cloned recombinant DNA into zygotes. Although the factors that affect transformation frequencies and integration sites are still unknown, such techniques offer a number of exciting prospects. Research models for human disease coula be artificially created and desirable characteristics in agricultural animals could be - hanced. . The theme of cell-to-cell transfer is continued in Chapters 2 and 3. Chapter 2 describes pronuclear transplantation by Sendai virus-induced fusion of the karyoplast with the enucleated embryo. Using this procedure, it has been dem onstrated that both male and female genomes are essential for normal develop ment, although the reason for this is not yet understood. Chapter 3 describes studies on the fusion of whole oocytes. .

updated throughout with new information on sexing embryos, sexing semen, marketing, cloning as well as the basics and economics of this technology. Glossary.