Learn how AI and data science are upending the worlds of biology and medicine In Silico Dreams: How Artificial Intelligence and Biotechnology Will Create the Medicines of the Future delivers an illuminating and fresh perspective on the convergence of two powerful technologies: AI and biotech. Accomplished genomics expert, executive, and author Brian Hilbush offers readers a brilliant exploration of the most current work of pioneering tech giants and biotechnology startups who have already started disrupting healthcare. The book provides an in-depth understanding of the sources of innovation that are driving the shift in the pharmaceutical industry away from serendipitous therapeutic discovery and toward engineered medicines and curative therapies. In this fascinating book, you'll discover: An overview of the rise of data science methods and the paradigm shift in biology that led to the in silico revolution An outline of the fundamental breakthroughs in AI and deep learning and their applications across medicine A compelling argument for the notion that AI and biotechnology tools will rapidly accelerate the development of therapeutics A summary of innovative breakthroughs in biotechnology with a focus on gene editing and cell reprogramming technologies for therapeutic development A guide to the startup landscape in AI in medicine, revealing where investments are poised to shape the innovation base for the pharmaceutical industry Perfect for anyone with an interest in scientific topics and technology, In Silico Dreams also belongs on the bookshelves of decision-makers in a wide range of industries, including healthcare, technology, venture capital, and government.

This fascinating reference covers the major topics concerning dreaming and sleep, based on the latest empirical evidence from sleep research as well as drawn from a broad range of dream-related interdisciplinary contexts, including history and anthropology. While many books have been written on the subject of sleep and dreams, no other resource has provided the depth of empirical evidence concerning sleep and dream phenomena nor revealed the latest scientific breakthroughs in the field. Encyclopedia of Sleep and Dreams: The Evolution, Function, Nature, and Mysteries of Slumber explores the evolution, nature, and functions of sleep and dreams. The encyclopedia is divided into two volumes and is arranged alphabetically by entry. Topics include nightmares and their treatment, how sleep and dreams change across the lifetime, and the new field of evolution of sleep and dream. While this book includes ample material on the science of sleep and dreams, content is drawn from a broad range of disciplinary contexts, including history and anthropology.

It is well known that high-tech startups need to innovate to survive, yet the failure rate for innovation is shockingly high. Nearly three out of four new products or services, i.e., their startups, miss their revenue and profit goals–or fail entirely. It’s a misconception that high-tech startups fail only because of the failing products or finances. The failures could also be because of erroneous choice of technology platforms, development teams or methodology, or even the project execution. Accordingly, this book takes a holistic view of a startups’ aesthetics that enables it to become attractive for all stakeholders especially investors in all aspects of its operations at all stages of its lifecycle. This book: Looks at aspects of venture capital financing and what investors look for in a contemporary startup. Shows how only an overarching aspiration for a startup to become a Unicorn is sufficient to explain the typical characteristics of legendry Silicon Valley Unicorns like Google, Facebook, LinkedIn, and Twitter. Covers major application areas of current/future interest, namely, intelligent systems, intelligent assistants, wireless sensor networks, Internet of Things (IoT), and blockchain systems. Introduces the contemporary skills-set in demand for Startups. To succinctly cover all aspects of a contemporary startup, Unleashing the Startup Unicorn is organized to reflect the natural grouping of competencies that are essential for entrepreneurial ventures–from conception to successful exit. To understand and analyze these competencies, the book uses an extended 9S model inspired by the pioneering McKinsey 7S model.

This book explores the role of in silico deployment in connection with modulation techniques for improving sustainability and competitiveness in the agri-food sector; pharmacokinetics and molecular docking studies of plant-derived natural compounds; and their potential anti-neurodegenerative activity. It also investigates biochemical pathways for bacterial metabolite synthesis, fungal diversity and plant-fungi interaction in plant diseases, methods for predicting disease-resistant candidate genes in plants, and genes-to-metabolites and metabolites-to-genes approaches for predicting biosynthetic pathways in microbes for natural product discovery. The respective chapters elaborate on the use of in situ methods to study biochemical pathways for bacterial metabolite synthesis; tools for plant metabolites in defence; plant secondary metabolites in defence; plant growth metabolites; characterisation of plant metabolites; and identification of plant derived metabolites in the context of plant defence. The book offers an unprecedented resource, highlighting state-of-the-art research work that will greatly benefit researchers and students alike, not only in the field of agriculture but also in many disciplines in the life sciences and plant sciences.

The pharmaceutical industry relies on numerous well-designed experiments involving high-throughput techniques and in silico approaches to analyze potential drug targets. These in silico methods are often predictive, yielding faster and less expensive analyses than traditional in vivo or in vitro procedures. In Silico Technologies in Drug Target Ide

• Includes conversations with Duncan Trussell, Graham Hancock, Grant Morrison, Hamilton Morris, Erik Davis, Julia Mossbridge, Rupert Sheldrake, and others • Explores the possibility of human extinction, Simulation Theory, Virtual Reality and lucid dreaming, space migration, DMT research, and advanced robotics • Delves deep into the relationship between psychedelics and ecological awareness Between war, inequality, biosphere collapse, climate change, and destabilizing advances in technology like AI, humankind is confronted with an almost insurmountable array of challenges. Yet many brilliant experts are working on outside-the-box solutions, looking to psychedelic-inspired visions of the future to lead humanity through these crises. In a series of conversations with leading minds in consciousness studies, psychedelic culture, anthropology, chemistry, and other disciplines, author David Jay Brown elicits answers to some of the most thought-provoking questions about our origins, our present situation, and the future of humanity and the Earth. Brown and these luminaries explore topics as diverse as potential human extinction, the relationship between psychedelics and ecological consciousness, simulation theory, virtual reality and lucid dreaming, the consciousness-altering effects of the pandemic, space migration and contact with alien intelligence, and DMT research and advanced robotics. Whether he’s speaking to podcaster Duncan Trussell about the Singularity, comic book author Grant Morrison about magick and the occult, or neuroscientist Julia Mossbridge about psychic phenomena, Brown’s spirited interview approach helps draw profound insights from these cutting-edge thinkers. What, he asks, are the implications of our understanding of consciousness, particularly altered states—and how might entheogens help raise ecological awareness to impact the future of our species? In this curated colletion of interviews, Brown seeks to find out.

When I got into India’s top-most software company, I thought, Dude, your life is set. 'My future was bright, my parents were damn proud of me, my hot girlfriend and I planned a great life together. Then things began to happen... crazy things I had not foreseen... I was forced to reassess my dreams... to reconfigure the way I thought... to look again at this thing they call love... I am Karthik S. And this is my story.'