Our understanding of the biology of bladder cancer has advanced remarkably since the second edition of 'Fast Facts: Bladder Cancer' was published in 2006. Five new immunotherapies targeting the PD-1 axis were approved in 2016 and 2017 for the treatment of advanced bladder cancer, reflecting this transformative explosion in knowledge about the biology of the disease. This new era of targeted treatment offers hope to patients, particularly those with advanced disease. However, for clinicians it means a lot to understand in terms of how these immunotherapies are integrated into the treatment paradigm. Who they are suitable for? When are they best used? What is the optimal sequence of treatments for individual patients? This third edition of 'Fast Facts: Bladder Cancer' has been updated extensively throughout by two new authors, bringing a fresh perspective. Key updates include: • the latest understanding of pathology and biology • current standards for investigation, imaging and diagnosis • the critical role that awareness of the significance of hematuria among patients and primary care health professionals can make to earlier detection at curable stages of the disease • the roles of drugs, surgery and radiation therapy in treatment at different stages of bladder cancer, and when and how best to intervene, aided by understanding of the risk factors for disease relapse and progression • a new chapter about immunotherapy for bladder cancer • future trends in a rapidly evolving field. 'Fast Facts: Bladder Cancer' is a concise guide that will be of value to clinicians and health professionals involved in the detection and treatment of bladder cancer. This highly readable resource provides a comprehensive and current view of this complex disease, enabling informed discussions with patients. Contents: • Epidemiology and etiology • Pathology and biology • Clinical presentation • Investigations • Management of non-muscle-invasive disease • Management of muscle-invasive disease • Management of advanced and metastatic disease • Immunotherapy • Future trends • Useful resources

The incidence of bladder cancer has risen since the 1980s. Around 55,000 new cases of bladder cancer are diagnosed in the USA and 10,000 in the UK, each year. Bladder cancer is the fourth most frequently occurring cancer in males in the USA nd the eighth most common cause of mortality. In the UK, it accounts for 5000 deaths per annum. This text reviews existing knowledge and management.

The term ‘bladder disorders’ encompasses a number of lower urinary tract dysfunctions and abnormalities that negatively affect quality of life. Some can cause considerable morbidity and even mortality. Three internationally recognized authors with different areas of expertise – a leading British urogynecologist, a chief of urology listed as one of America's "Best Doctors", and an American continence expert - have ensured that this second edition of 'Fast Facts: Bladder Disorders' is internationally relevant to the non-specialist working within a multidisciplinary team. Based on robust evidence and clinical experience, and supported by superb illustrations, this fact-filled handbook covers everything you will need to recognize the symptoms and signs of a wide range of bladder disorders from urinary incontinence to hematuria to UTIs. It also provides an excellent overview of basic pathophysiology, and will help practitioners initiate screening and assessment and, where appropriate, treatment. Contents: • Anatomy and function of the urinary system • Assessment • Urinary incontinence • The overactive bladder and urgency incontinence • Voiding problems • Hematuria • Urinary tract infections and cystitis • Nocturnal symptoms • Neuropathic bladder dysfunction • Special considerations • Useful resources

Cancer of the urinary bladder (UBC) is a common tumour, and most primary care physicians can expect to see two or three new cases each year. Since many patients will have a good prognosis, the number of patients with bladder cancer in the population of every practice will be much larger.This book clearly and succinctly provides the facts that those treating and caring for patients with UBC will need to know. It is a concise guide to clinical practice for family physicians, specialist nurses, and junior doctors and will be of interest to patients keen to understand more about their condition.- Offers a clear explanation of therapeutic options to help doctor and patient make informed treatment choices- Includes the evidence base for diagnosis and management of UBC- New expanded coverage on chemotherapy and radiotherapy- Offers greater detail on oncology and palliation- Concluding section on Future Trends reviews prevention, earlier diagnosis, improvements to existing treatments and emerging therapies