Ethical questions about the use of animals and humans in research remain among the most vexing within both the scientific community and society at large. These often rancorous arguments have gone on, however, with little awareness of their historical antecedents. Experimentation on animals and particularly humans is often assumed to be a uniquely modern phenomenon, but the ideas and attitudes that encourage the biological and medical sciences to experiment on living creatures date from the earliest expression of Western thought. Here, Anita Guerrini looks at the history of these practices from vivisection in ancient Alexandria to present-day battles over animal rights and medical research employing human subjects. Guerrini discusses key historical episodes, including the discovery of blood circulation, the development of smallpox and polio vaccines, and recent AIDS research. She also explores the rise of the antivivisection movement in Victorian England, the modern animal rights movement, and current debates over gene therapy.--From publisher description.

Animal experimentation has been one of the most controversial areas of animal use, mainly due to the intentional harms inflicted upon animals for the sake of hoped-for benefits in humans. Despite this rationale for continued animal experimentation, shortcomings of this practice have become increasingly more apparent and well-documented. However, these limitations are not yet widely known or appreciated, and there is a danger that they may simply be ignored. The 51 experts who have contributed to Animal Experimentation: Working Towards a Paradigm Change critically review current animal use in science, present new and innovative non-animal approaches to address urgent scientific questions, and offer a roadmap towards an animal-free world of science.

Drs. Greek have written 2 books on why using animals as models for humans is not the best way to conduct medical research and drug testing. During their lectures and debates, the most commonly asked question was, "Well. What will we use if we don't use animals?" What Will We Do If We Don't Experiment On Animals? Medical Research for the Twenty-first Century is the answer to that question. Drs. Greek explain briefly why one species cannot predict drug response for another and describe what research and testing methods should be used today instead of animals. They also describe where our biomedical research dollars should be spent if we are to have cures for cancer, AIDS, and Alzheimer's. This book will appeal to science-trained and general audiences, animal lovers and science readers, public policy analysts, students, patients and patient support groups, and government watchdog groups. What Will We Do If We Don't Experiment On Animals? Medical Research for the Twenty-first Century takes medical research out of the nineteenth and into the 21st century.

Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.

Examining the ideas and attitudes that encourage scientists to experiment on living creatures, what their justifications are, and how these have changed over time. Experimentation on animals—particularly humans—is often assumed to be a uniquely modern phenomenon. But the ideas and attitudes that encourage biological and medical scientists to experiment on living creatures date from the earliest expressions of Western thought. In Experimenting with Humans and Animals, Anita Guerrini looks at the history of these practices and examines the philosophical and ethical arguments that justified them. Guerrini discusses key historical episodes in the use of living beings in science and medicine, including the discovery of blood circulation, the development of smallpox and polio vaccines, and recent research in genetics, ecology, and animal behavior. She also explores the rise of the antivivisection movement in Victorian England, the modern animal rights movement, and current debates over gene therapy and genetically engineered animals. We learn how perceptions and understandings of human and animal pain have changed; how ideas of class, race, and gender have defined the human research subject; and that the ethical values of science seldom stray far from the society in which scientists live and work. Thoroughly rewritten and updated, with new material in every chapter, the book emphasizes a broader understanding of experimentation and adds material on gene therapy, self-experimentation, and prisoners and slaves as experimental subjects. A new chapter brings the story up to the present while reflecting on the current regulatory scene, new developments in science, and emerging genomics. Experimenting with Humans and Animals offers readers a context within which to understand more fully the responsibility we all bear for the suffering inflicted on other living beings in the name of scientific knowledge.

Animals and Medicine: The Contribution of Animal Experiments to the Control of Disease offers a detailed, scholarly historical review of the critical role animal experiments have played in advancing medical knowledge. Laboratory animals have been essential to this progress, and the knowledge gained has saved countless lives—both human and animal. Unfortunately, those opposed to using animals in research have often employed doctored evidence to suggest that the practice has impeded medical progress. This volume presents the articles Jack Botting wrote for the Research Defence Society News from 1991 to 1996, papers which provided scientists with the information needed to rebut such claims. Collected, they can now reach a wider readership interested in understanding the part of animal experiments in the history of medicine—from the discovery of key vaccines to the advancement of research on a range of diseases, among them hypertension, kidney failure and cancer.This book is essential reading for anyone curious about the role of animal experimentation in the history of science from the nineteenth century to the present.

At present, human beings worldwide are using an estimated 115.3 million animals in experiments ”a normalization of the unthinkable on an immense scale. In terms of harm, pain, suffering, and death, animal experiments constitute one of the major moral issues of our time. Given today's deeper understanding of animal sentience, we must afford animals a special moral consideration that precludes their use in experiments. The Ethical Case against Animal Experiments begins with a groundbreaking and comprehensive ethical critique of the practice of animal experiments by the Oxford Centre for Animal Ethics. A second section offers original writings that engage with, and elaborate on, aspects of the Oxford Centre report. The essayists explore historical, philosophical, and personal perspectives that range from animal experiments in classical times to the place of necessity in animal research to one researcher's painful journey from researcher to opponent. A devastating look at a contemporary moral crisis, The Ethical Case against Animal Experiments melds logic to compassion to mount a powerful challenge to human cruelty.