Physical oncology has the potential to revolutionize cancer research and treatment. The fundamental rationale behind this approach is that physical processes, such as transport mechanisms for drug molecules within tissue and forces exchanged by cancer cells with tissue, may play an equally important role as biological processes in influencing progression and treatment outcome. This book introduces the emerging field of physical oncology to a general audience, with a focus on recent breakthroughs that help in the design and discovery of more effective cancer treatments. It describes how novel mathematical models of physical transport processes incorporate patient tissue and imaging data routinely produced in the clinic to predict the efficacy of many cancer treatment approaches, including chemotherapy and radiation therapy. By helping to identify which therapies would be most beneficial for an individual patient, and quantifying their effects prior to actual implementation in the clinic, physical oncology allows doctors to design treatment regimens customized to each patient’s clinical needs, significantly altering the current clinical approach to cancer treatment and improving the outcomes for patients.

Introduction to Mathematical Oncology presents biologically well-motivated and mathematically tractable models that facilitate both a deep understanding of cancer biology and better cancer treatment designs. It covers the medical and biological background of the diseases, modeling issues, and existing methods and their limitations. The authors introduce mathematical and programming tools, along with analytical and numerical studies of the models. They also develop new mathematical tools and look to future improvements on dynamical models. After introducing the general theory of medicine and exploring how mathematics can be essential in its understanding, the text describes well-known, practical, and insightful mathematical models of avascular tumor growth and mathematically tractable treatment models based on ordinary differential equations. It continues the topic of avascular tumor growth in the context of partial differential equation models by incorporating the spatial structure and physiological structure, such as cell size. The book then focuses on the recent active multi-scale modeling efforts on prostate cancer growth and treatment dynamics. It also examines more mechanistically formulated models, including cell quota-based population growth models, with applications to real tumors and validation using clinical data. The remainder of the text presents abundant additional historical, biological, and medical background materials for advanced and specific treatment modeling efforts. Extensively classroom-tested in undergraduate and graduate courses, this self-contained book allows instructors to emphasize specific topics relevant to clinical cancer biology and treatment. It can be used in a variety of ways, including a single-semester undergraduate course, a more ambitious graduate course, or a full-year sequence on mathematical oncology.

This new book covers the basics of oncology for all practitioners who are likely to provide health care to cancer patients, especially those who do not have an oncology or medical background. Cancer educator David O’Halloran provides a unique insight by bridging the gap between normal anatomy and what happens when cancer develops. Information is provided using a layered approach, starting with simple concepts of general cancer biology and moving through to more complicated aspects of specific tumour sites and cancer treatment. Easy to read and follow, Oncology: An Introduction for Nurses & Healthcare Professionals is written in such a way that non-specialist readers will quickly understand complex terminology and concepts, making them relatable and understandable for experienced and junior nurses alike. Logical and easy-to-follow approach Accessible language throughout – does not assume a prior level of knowledge Explains cancer terminology for non-experts Takes a graded approach to information to help learning Provides an understanding of cancer and how it progresses, how to link anatomy to the staging of cancer, and how to explain how modern cancer treatments work Invaluable in helping explain conditions and treatment to patients and families Self-assessment exercises throughout help test learning

This groundbreaking book presents a unique and practical approach to the evolving field of exercise oncology - the study of physical activity in the context of cancer prevention and control. Presenting the current state of the art, the book is sensibly divided into four thematic sections. Following an opening chapter presenting an overview and timeline of exercise oncology, the chapters comprising part I discuss primary cancer prevention, physical activity and survivorship, and the mechanisms by which these operate. Diagnosis and treatment considerations are discussed in part II, including prehabilitation, exercise during surgical recovery, infusion and radiation therapies, and treatment efficacy. Post-treatment and end-of-life care are covered in part III, including cardio-oncology, energetics and palliative care. Part IV presents behavioral, logistical and policy-making considerations, highlighting a multidisciplinary approach to exercise oncology as well as practical matters such as reimbursement and economics. Written and edited by experts in the field, Exercise Oncology will be a go-to practical resource for sports medicine clinicians, family and primary care physicians, oncologists, physical therapy and rehabilitation specialists, and all medical professionals who treat cancer patients.

"Basics of Oncology" provides an easily understood and general overview of the basic medical, scientific and clinical aspects of cancer. Causes, pathology, clinical features, diagnostic investigations, treatments and outcomes are all carefully explained and discussed, both for cancers in general and for the common cancers in individual countries. The reader will thereby be provided with an understanding of how and why people develop cancer, how the body reacts to cancer, what can be done to prevent the disease, and how the various cancers are best diagnosed and treated. The book will serve as a sound basis for the more detailed or specific studies that may be needed in different areas of practice and in different countries. It will be invaluable for students of medicine, nurse oncologists, students of medical sciences and other health professionals in all parts of the world.

A concise overview of the fundamental concepts of cancer biology, ideal for those with little or no background in the field. From cancer epidemiology and the underlying mechanisms, through to tumour detection and treatment, the comprehensive picture revealed will enable students to move into the cancer field with confidence.

Fundamentals of Radiation Oncology: Physical, Biological, and Clinical Aspects, Fourth Edition, is written by a team of renowned experts. This book is a must-have resource for anyone practicing radiation oncology. From basic principles to more-advanced planning and delivery of radiation therapy to treat cancer, this book is a go-to resource for mastering the art and science of radiation oncology. Recent advances in SRS, SBRT, proton therapy, an immunotherapy New chapters on adaptive radiotherapy, and artificial intelligence in radiation therapy IMRT and IGRT techniques are covered in depth in all clinical chapters Latest landmark studies provide evidence-based rationale for recommended treatments Radiation treatment toxicity and its management