What wonders of science will the 21st century bring? John Maddox takes up this challenge by describing precisely what remains to be discovered. Building on twenty-three years' experience at the helm of the world's preeminent science magazine, Nature, Maddox identifies new areas of discovery in physics, biology, health, intelligence, and global catastrophe. As Maddox shows, the rate of scientific discovery will continue to accelerate, hurtling us toward ever more exciting discoveries in the next century.