"In 1970 American neurosurgeon Robert White and his team carried out the first full head transplant in living monkeys. However, the resulting chimera was left tetraplegic and died a few days later. Fifty years on, the technology to perform a human cephalosomatic anastomosis is finally available. In this groundbreaking book, the pioneers of this new medical frontier bring together an international team of scientists to reveal for the first time the entire body of animal and human research and experimentation that made this breakthrough possible. Readers - professionals, journalists, educated laypersons- will get unadulterated access to the published and unpublished body of evidence that has shocked the world since 2013. Only a deep appreciation of this technology can inform the ethical debate that keeps raging on since 2013. Above all, the possibility of extending life raises profound dilemmas. This book brings clarity to the current debate and provides the instruments to make an informed decision on the most sensitive of subjects: overcoming death"--

The possibility of performing a full brain transfer from one living individual to another -a brain transplant- has been the staple of science fiction and the pet dream of many a neurosurgeon. Yet it is considered a technical impossibility. Now, after developing the technology that powers head transplantation, Prof Canavero describes the technology behind a full brain transplant. BRAVE, the Brain Anastomosis Venture, aims at achieving the first brain transplant in history as a device to extend life.

The mesmerizing biography of a brilliant and eccentric surgeon and his quest to transplant the human soul. In the early days of the Cold War, a spirit of desperate scientific rivalry birthed a different kind of space race: not the race to outer space that we all know, but a race to master the inner space of the human body. While surgeons on either side of the Iron Curtain competed to become the first to transplant organs like the kidney and heart, a young American neurosurgeon had an even more ambitious thought: Why not transplant the brain? Dr. Robert White was a friend to two popes and a founder of the Vatican’s Commission on Bioethics. He developed lifesaving neurosurgical techniques still used in hospitals today and was nominated for the Nobel Prize. But like Dr. Jekyll before him, Dr. White had another identity. In his lab, he was waging a battle against the limits of science, and against mortality itself—working to perfect a surgery that would allow the soul to live on after the human body had died. Mr. Humble and Dr. Butcher follows his decades-long quest into tangled matters of science, global politics, and faith, revealing the complex (and often murky) ethics of experimentation and remarkable innovations that today save patients from certain death. It’s an enthralling tale that offers a window into our greatest fears and our greatest hopes—and the long, strange journey from science fiction to science fact.

'Compelling' Christopher Hart, The Sunday Times 'A fascinating book' Daily Mail _______________________________________________________________ We think of transplant surgery as one of the medical wonders of the modern world -- but it's a lot older than you think. As ancient as the pyramids, its history is even more surprising. In Spare Parts, cultural historian Paul Craddock takes us on a fascinating journey and unearths incredible untold stories, from Indian surgeons regrafting lost noses in the sixth century BC, to the seventeenth century architect who helped pioneer blood transfusions, to the French seamstress whose needlework paved the way for kidney transplants in the early 1900s. Expertly weaving together philosophy, science and cultural history, Spare Parts explores how transplant surgery has constantly tested the boundaries between human, animal and machine. It shows us that the history -- and future -- of transplant surgery is tied up with questions not only about who we are, but also what we are, and what we might become. _______________________________________________________________ 'By turns delightful and disturbing . . . A thoroughly engrossing read that I couldn't put down' LINDSEY FITZHARRIS, author of The Facemaker and The Butchering Art 'Spare Parts is a fascinating read filled with adventure, delight and surprise' RAHUL JANDIAL, surgeon and author of Life on a Knife's Edge 'This is a joyful romp through a fascinating slice of medical history' WENDY MOORE, author of The Knife Man

Saving lives through organ transplantation has become increasingly possible thanks to advances in research and care. Today, the complex field of transplantation continues to develop rapidly, fuelled by demographic change and further evolutions in scientific understanding. The Oxford Textbook of Transplant Anaesthesia and Critical Care has been written and edited by pioneers in the field of organ transplantation with an international team of authors, in order to equip anaesthetists and intensivists with the knowledge and training necessary to provide high quality and evidence-based care. The text addresses fundamentals aspects of scientific knowledge, care of the donor patient, transplant ethics and special considerations. Dedicated sections address each of the major organs; kidney, pancreas, liver, heart and lung, intestinal and multivisceral. Within each organ-based section, expert authors explore underlying disease, planning for transplantation, specialized procedures, perioperative and critical care management as well as post-transplant considerations. Focus points for future developments in transplant immunology are also set out, inspiring current practitioners to engage with current clinical research and help participate in the further advancement of the science of transplantation. The print edition of the Oxford Textbook of Transplant Anaesthesia and Critical Care comes with a year's access to the online version on Oxford Medicine Online. By activating your unique access code, you can read and annotate the full text online, follow links from the references to primary research materials, and view, enlarge and download all the figures and tables.

This first open access European CAR-T Handbook, co-promoted by the European Society for Blood and Marrow Transplantation (EBMT) and the European Hematology Association (EHA), covers several aspects of CAR-T cell treatments, including the underlying biology, indications, management of side-effects, access and manufacturing issues. This book, written by leading experts in the field to enhance readers’ knowledge and practice skills, provides an unparalleled overview of the CAR-T cell technology and its application in clinical care, to enhance readers’ knowledge and practice skills.

This is an open access book with CC BY 4.0 license. This comprehensive open access textbook provides a comprehensive coverage of principles and practice of oral and maxillofacial surgery. With a range of topics starting from routine dentoalveolar surgery to advanced and complex surgical procedures, this volume is a meaningful combination of text and illustrations including clinical photos, radiographs, and videos. It provides guidance on evidence-based practices in context to existing protocols, guidelines and recommendations to help readers deal with most clinical scenarios in their daily surgical work. This multidisciplinary textbook is meant for postgraduate trainees, young practicing oral surgeons and experienced clinicians, as well as those preparing for university and board certification exams. It also aids in decision-making, the implementation of treatment plans and the management of complications that may arise. This book is an initiative of Association of Oral and Maxillofacial Surgeons of India (AOMSI) to its commitment to academic medicine. As part of this commitment, this textbook is in open access to help ensure widest possible dissemination to readers across the world. ; Open access Unique presentation with contents divided into color-coded core competency gradations Covers all aspects of oral and maxillofacial surgery Supplemented with videos of all commonly carried out procedures as operative video Every chapter or topic concludes with "future perspective" and addresses cutting edge advances in each area Every topic has a pull out box that provides the most relevant systematic reviews/ key articles to every topic.