Like sharks, epidemic diseases always lurk just beneath the surface. This fast-paced history of their effect on mankind prompts questions about the limits of scientific knowledge, the dangers of medical hubris, and how we should prepare as epidemics become ever more frequent. Ever since the 1918 Spanish influenza pandemic, scientists have dreamed of preventing catastrophic outbreaks of infectious disease. Yet, despite a century of medical progress, viral and bacterial disasters continue to take us by surprise, inciting panic and dominating news cycles. From the Spanish flu and the 1924 outbreak of pneumonic plague in Los Angeles to the 1930 'parrot fever' pandemic and the more recent SARS, Ebola, and Zika epidemics, the last 100 years have been marked by a succession of unanticipated pandemic alarms. Like man-eating sharks, predatory pathogens are always present in nature, waiting to strike; when one is seemingly vanquished, others appear in its place. These pandemics remind us of the limits of scientific knowledge, as well as the role that human behaviour and technologies play in the emergence and spread of microbial diseases.

A Financial Times Best Book of the Year The most timely and informative history book you will read this year, tracing a century of pandemics, with a new chapter on COVID-19. Ever since the 1918 Spanish influenza pandemic, scientists have dreamed of preventing catastrophic outbreaks of infectious disease. Yet, despite a century of medical progress, viral and bacterial disasters continue to take us by surprise, inciting panic and dominating news cycles. From the Spanish flu and the 1924 outbreak of pneumonic plague in Los Angeles, to the 1930 'parrot fever' pandemic and the more recent SARS, Ebola, Zika and - now - COVID-19 epidemics, the last 100 years have been marked by a succession of unanticipated pandemic alarms. In The Pandemic Century, Mark Honigsbaum chronicles 100 years of history in 10 outbreaks. Bringing us right up-to-date with a new chapter on COVID-19, this fast-paced, critically-acclaimed book combines science history, medical sociology and thrilling front-line reportage to deliver the story of our times. As we meet dedicated disease detectives, obstructive public health officials, and gifted scientists often blinded by their own expertise, we come face-to-face with the brilliance and medical hubris shaping both the frontier of science - and the future of humanity's survival.

With a New Chapter and Updated Epilogue on Coronavirus A Financial Times Best Health Book of 2019 and a New York Times Book Review Editors’ Choice "Honigsbaum does a superb job covering a century’s worth of pandemics and the fears they invariably unleash." —Howard Markel, MD, PhD, director of the Center for the History of Medicine, University of Michigan How can we understand the COVID-19 pandemic? Ever since the 1918 Spanish influenza pandemic, scientists have dreamed of preventing such catastrophic outbreaks of infectious disease. Yet despite a century of medical progress, viral and bacterial disasters continue to take us by surprise, inciting panic and dominating news cycles. In The Pandemic Century, a lively account of scares both infamous and less known, medical historian Mark Honigsbaum combines reportage with the history of science and medical sociology to artfully reconstruct epidemiological mysteries and the ecology of infectious diseases. We meet dedicated disease detectives, obstructive or incompetent public health officials, and brilliant scientists often blinded by their own knowledge of bacteria and viruses—and see how fear of disease often exacerbates racial, religious, and ethnic tensions. Now updated with a new chapter and epilogue.

In November 2018, an ad hoc planning committee at the National Academies of Sciences, Engineering, and Medicine planned two sister workshops held in Washington, DC, to examine the lessons from influenza pandemics and other major outbreaks, understand the extent to which the lessons have been learned, and discuss how they could be applied further to ensure that countries are sufficiently ready for future pandemics. This publication summarizes the presentations and discussions from both workshops.

In the past two decades, several pandemics have ravaged the globe, giving us several lessons on infectious disease epidemiology, the importance of initial detection and characterization of outbreak viruses, the importance of viral epidemic prevention steps, and the importance of modern vaccines. Pandemic Outbreaks in the Twenty-First Century: Epidemiology, Pathogenesis, Prevention, and Treatment summarizes the improvements in the 21st century to overcome / prevent / treat global pandemic with future prospective. Divided into 9 chapters, the book begins with an in-depth introduction to the lessons learned from the first pandemic of the 21st century. It describes the history, present and future in terms of detection, prevention and treatment. Followed by chapters on the outbreak, treatment strategies and clinical management of several infectious diseases like MERS, SARD and COVID 19, Pandemic Outbreaks in the Twenty-First Century: Epidemiology, Pathogenesis, Prevention, and Treatment, presents chapters on immunotherapies and vaccine technologies to combat pandemic outbreak and challenges. The book finishes with a chapter on the current knowledge and technology to control pandemic outbreaks. All are presented in a practical short format, making this volume a valuable resource for very broad academic audience. Provides insight to the lessons learned from past pandemics Gives recommendations, future direction in terms of detection, prevention and treatment of pandemics Guides readers through the status and recent developments of vaccines to overcome or prevent pandemics Shows how to enhance the host innate immunity in infectious diseases Includes a chapter on immunotherapies to combat pandemic outbreaks

NEW YORK TIMES BESTSELLER • From the Pulitzer Prize-winning author of The Looming Tower—a riveting thriller and “all-too-convincing chronicle of science, espionage, action and speculation” (The Wall Street Journal). At an internment camp in Indonesia, forty-seven people are pronounced dead with acute hemorrhagic fever. When epidemiologist Henry Parsons travels there on behalf of the World Health Organization to investigate, what he finds will have staggering repercussions. Halfway across the globe, the deputy director of U.S. Homeland Security scrambles to mount a response to the rapidly spreading pandemic leapfrogging around the world, which she believes may be the result of an act of biowarfare. And a rogue experimenter in man-made diseases is preparing his own terrifying solution. As already-fraying global relations begin to snap, the virus slashes across the United States, dismantling institutions and decimating the population. With his own wife and children facing diminishing odds of survival, Henry travels from Indonesia to Saudi Arabia to his home base at the CDC in Atlanta, searching for a cure and for the origins of this seemingly unknowable disease. The End of October is a one-of-a-kind thriller steeped in real-life political and scientific implications, filled with the insight that has been the hallmark of Wright’s acclaimed nonfiction and the full-tilt narrative suspense that only the best fiction can offer.

A wide-ranging study that illuminates the connection between epidemic diseases and societal change, from the Black Death to Ebola This sweeping exploration of the impact of epidemic diseases looks at how mass infectious outbreaks have shaped society, from the Black Death to today. In a clear and accessible style, Frank M. Snowden reveals the ways that diseases have not only influenced medical science and public health, but also transformed the arts, religion, intellectual history, and warfare. A multidisciplinary and comparative investigation of the medical and social history of the major epidemics, this volume touches on themes such as the evolution of medical therapy, plague literature, poverty, the environment, and mass hysteria. In addition to providing historical perspective on diseases such as smallpox, cholera, and tuberculosis, Snowden examines the fallout from recent epidemics such as HIV/AIDS, SARS, and Ebola and the question of the world’s preparedness for the next generation of diseases.