"The Lancet Handbook of Essential Concepts in Clinical Research speaks to two audiences: those who read and those who conduct research. Clinicians are medical detectives by training. For each patient, they assemble clinical clues to establish causes (e.g. diagnoses) of signs and symptoms. The task involves both clinical acumen and knowledge of medical research. This book helps guide clinicians through this detective work, by enabling them to make sense of research and to review medical literature critically. It will also be invaluable to researchers who conduct clinical research, particularly randomized controlled trials. Building on previously published, peer-reviewed articles from The Lancet, this handbook is essential for busy clinicians and active researchers interested in research methods."--BOOK JACKET.

The global response to the COVID-19 pandemic is the greatest science policy failure in a generation. We knew this was coming. Warnings about the threat of a new pandemic have been made repeatedly since the 1980s and it was clear in January that a dangerous new virus was causing a devastating human tragedy in China. And yet the world ignored the warnings. Why? In this short and hard-hitting book, Richard Horton, editor of the medical journal The Lancet, scrutinizes the actions that governments around the world took – and failed to take – as the virus spread from its origins in Wuhan to the global pandemic that it is today. He shows that many Western governments and their scientific advisors made assumptions about the virus and its lethality that turned out to be mistaken. Valuable time was lost while the virus spread unchecked, leaving health systems unprepared for the avalanche of infections that followed. Drawing on his own scientific and medical expertise, Horton outlines the measures that need to be put in place, at both national and international levels, to prevent this kind of catastrophe from happening again. Were supposed to be living in an era where human beings have become the dominant influence on the environment, but COVID-19 has revealed the fragility of our societies and the speed with which our systems can come crashing down. We need to learn the lessons of this pandemic and we need to learn them fast because the next pandemic may arrive sooner than we think.

This unique introduction to the essentials of global health has been constructed by medical students from all over the world through the help of Medsin (now Students for Global Health) and the International Federation of Medical Students’ Association (IFMSA). The global student and trainee author team, recruited and guided initially by Drs Dan and Felicity Knights (themselves students and officers of Medsin when work commenced), identified the key areas to be covered. Then the book they put together was edited by two experts in the field: Mr B Sethia and Professor Parveen Kumar. Royalties raised from this book go to a grant fund for student global health projects. Written by medical students and junior doctors from Students for Global Health and the International Federation of Medical Students’ Association (IFMSA). Edited by two experts in the field, Mr B Sethia and Professor Parveen Kumar. Royalties go to a grant fund for student global health projects.

This book systematically and comprehensively discusses the biological, epidemiological and clinical characteristics of the hepatitis E virus (HEV). It presents current knowledge of HEV and explores experimental methods, treatment and prevention of HEV. First identified in the 1980s and cloned in 1990, HEV is the causative agent of Hepatitis E, which mainly occurs in developing regions, such as Southeast Asia, Middle East and Africa, and significantly affects the health of the people in these areas. It is estimated that a third of the world’s population has been infected with HEV, which is transmitted via the fecal-oral route and can infect both human and animals. The book provides an overview of HEV from benchside to bedside. It is a valuable resource for researchers in the field and those in the pharmaceutical industry developing HEV vaccines, as well as physicians involved in identifying and treating those infected with the virus.

Challenges popular misconceptions about fats and nutrition science, revealing the distorted claims of nutrition studies while arguing that more dietary fat can lead to better health, wellness, and fitness.

This text covers oncology in over 80 cases. It includes coverage of issues in supportive care and symptom control and a guide to oncology information and evidence databases on the Internet.

All I Eat Is Medicine charts the lives of individuals and the operation of institutions in the thick of the AIDS epidemic in Mozambique during the global scale-up of treatment for HIV/AIDS at the turn of the twenty-first century. Even as the AIDS treatment scale-up saved lives, it perpetuated the exploitation and exclusion that was implicated in the propagation of the epidemic in the first place. This book calls attention to the global social commitments and responsibilities that a truly therapeutic global health requires.