Computer simulation experiments are essential to modern scientific discovery, whether that be in physics, chemistry, biology, epidemiology, ecology, engineering, etc. Surrogates are meta-models of computer simulations, used to solve mathematical models that are too intricate to be worked by hand. Gaussian process (GP) regression is a supremely flexible tool for the analysis of computer simulation experiments. This book presents an applied introduction to GP regression for modelling and optimization of computer simulation experiments. Features: • Emphasis on methods, applications, and reproducibility. • R code is integrated throughout for application of the methods. • Includes more than 200 full colour figures. • Includes many exercises to supplement understanding, with separate solutions available from the author. • Supported by a website with full code available to reproduce all methods and examples. The book is primarily designed as a textbook for postgraduate students studying GP regression from mathematics, statistics, computer science, and engineering. Given the breadth of examples, it could also be used by researchers from these fields, as well as from economics, life science, social science, etc.

If you need help having a baby, reproductive technology can supply the answer. But it also raises a host of questions that won’t arise until after the child is born: What will you say to “Where did I come from?” when the answer includes a donor or surrogate? Will knowing the truth about how you conceived make your child love you less? Will having a baby with someone else strain your relationship with your spouse or partner? What will grandparents, family members, friends, and coworkers think? Dr. Diane Ehrensaft--a developmental and clinical psychologist who’s worked with families formed using assisted reproductive technology for more than 20 years--helps you anticipate the big questions and find solutions that are right for you and your loved ones. Dr. Ehrensaft offers information, support, and straightforward advice for coping with private worries, confronting public prejudices, and raising happy, healthy children. Single or married, straight or gay, anyone looking forward to the joys and challenges of building a family with the help of a donor or surrogate will discover a wealth of thought-provoking ideas and fresh insights in this sensitive, practical, and positive book.

"The prequel to the hit sci-fi graphic novel"--Cover.

Reprint of the original, first published in 1875.

The complexity of Surrogacy is arguably made even more so by the very nature of it being a decision many families reach due to the greatest of emotional challenges. There are so many opportunities for things to go wrong, but also the greatest of happy outcomes for so many families too. As a specialist surrogacy lawyer and a surrogate in 2018, Sarah Jefford has observed many surrogacy teams both flourish and struggle, and that has led to this very important book. In order to maximise every potential for things to go well for both intended parents and surrogate mothers, we need to make informed decisions that protect the interests of everyone involved, but most importantly that are in the best interests of the children - those who are already here, and those who will be in the future. If you want to know answers to the questions of how does surrogacy work, and the surrogate mother process, then this book will be your best place to start. But keep it handy throughout the entire process so that as your journey progresses, you will be able to understand the many aspects of surrogate pregnancy, intended parents roles, and each other's vital roles in creating a family together.