Quality of life studies form an essential part of the evaluation of any treatment. Written by two authors who are well respected within this field, Quality of Life: The Assessment, Analysis and Interpretation of Patient-reported Outcomes, Second Edition lays down guidelines on assessing, analysing and interpreting quality of life data. The new edition of this standard book has been completely revised, updated and expanded to reflect many methodological developments emerged since the publication of the first edition. Covers the design of instruments, the practical aspects of implementing assessment, the analyses of the data, and the interpretation of the results Presents all essential information on Quality of Life Research in one comprehensive volume Explains the use of qualitative and quantitative methods, including the application of basic statistical methods Includes copious practical examples Fills a need in a rapidly growing area of interest New edition accommodates significant methodological developments, and includes chapters on computer adaptive testing and item banking, choosing an instrument, systematic reviews and meta analysis This book is of interest for everyone involved in quality of life research, and it is applicable to medical and non-medical, statistical and non-statistical readers. It is of particular relevance for clinical and biomedical researchers within both the pharmaceutical industry and practitioners in the fields of cancer and other chronic diseases. Reviews of the First Edition – Winner of the first prize in the Basis of Medicine Category of the BMA Medical Book Competition 2001: “This book is highly recommended to clinicians who are actively involved in the planning, analysis and publication of QoL research.” CLINICAL ONCOLOGY “This book is highly recommended reading.” QUALITY OF LIFE RESEARCH

Memo: For Ministry of Strange, Unusual, and Impossible Things Operatives Only RE: The Ministry of SUITs by Paul Gamble (winner of the Eilís Dillon award for a first children’s book) A series of strange incidents have been reported in Belfast: * Oddball kids are going missing * There are several unconfirmed signs of pirates. * A wild bear known to be a very sore loser at musical statues has escaped from the museum and is on the rampage. Fortunately, our newest recruits, Jack Pearse, a curious boy skilled at logical thinking and seeing what's actually there, and Trudy Emerson, the most dangerous girl in his school, are on the case. As per Ministry policy, they are currently being trained in the use of The Speed (patent pending) and will have full access to Ministry supplies (assuming they manage to navigate the paperwork without going insane), so we are confident that they will succeed in their mission to discover and foil this villainous plot. Please provide all assistance possible, as a) they don't know who they are actually up against, b) the world is much stranger than they realized, and c) they are only 12 and have to be in bed by 10 p.m. P.S.-Could all Ministry operatives who have borrowed dinosaurs in the past two weeks please return them? We're running low on inventory.

The Chemotherapy Source Book, Fourth Edition pulls together all the current information on the chemotherapeutic management of cancer patients, including choice of chemotherapeutic agents, use of combinations, and toxicity of individual drugs. Organized by disease site, the book brings together pharmacologic and patient management information in one source that clinicians can consult for any question encountered in the delivery of chemotherapy. This updated Fourth Edition includes new drugs as well as new indications for older drugs. Content has been streamlined to provide essential information more quickly for the busy practitioner. Plus, this edition is softcover for greater portability and convenience.

This highly popular introduction to confidence intervals has been thoroughly updated and expanded. It includes methods for using confidence intervals, with illustrative worked examples and extensive guidelines and checklists to help the novice.

In this breath-taking debut novel, two worlds—and timelines—collide when ten-year-old Kara discovers mysterious footprints in the snow that lead her to another place entirely, perfect for fans of When You Reach Me and Echo. When mysterious footprints appear in the Stockholm snow, ten-year-old Kara attempts to discover where they’ve come from and who they belong to. They lead Kara to Rebecca, a thirteen-year-old Jewish girl, and her younger brother Samuel. Before long Kara realizes Rebecca and Samuel are refugees from another time—World War II—who are trying to find their way home. Kara discovers that her friends are trapped in a time loop, and they must make it to the British plane that lands near their hideout in order to make it out alive. With unexpected help, Kara travels into the time split to help save her friends. Matthew Fox’s lyrical prose—both haunting and uplifting—invites readers into an otherworldly setting grounded in history.

Dylan's mum thinks he's on the school Geography trip. Dylan's teacher thinks he's at home with the flu. In fact he's 30,000 feet up in the air on the way to Brazil. When Dylan's farm is snatched away by a huge global company, he can't just sit back and watch. But the journey to rescue his home takes him deep into the heart of the Amazon. With Floyd, a friend he's not sure of, and Lucia, a street kid armed with a thesaurus and a Great Dane puppy, he uncovers dark and dangerous secrets, and learns some surprising truths. 'Wow! What a book! It's riveting, it's moving, it's topical, it's superb! ... superb writing, brilliant characters, a glorious adventure and the warmest of heart. Amazing!' Malachy Doyle 'Emma Rea has written a beautifully researched adventure which encompasses the Welsh countryside and the Amazon. The unfolding friendship between Welsh Dylan and Brazilian Lucia is fabulous, and the clever plot sweeps along like a boat in a current.' Sue Wallman 'When nature-loving Dylan, 12, discovers his family farm in Wales (beautifully evoked) is being bought by a conglomerate based in Brazil, he plans to go there secretly to plead for the purchase to be abandoned ...This is the kind of adventure everyone likes to imagine when young, about being ingenious and brave and outwitting adults.' Nicolette Jones, Sunday Times Children's Book of the Week ' My Name is River... is a fantastically original adventure about a boy whose idyllic Welsh home is bought by an evil corporation. Desperate to save it, he travels from Birmingham to Brazil with his best friend. Rea's flight of imagination has two sympathetic heroes risking everything while lying their heads off. Packed with ecological indignation, it is both funny and timely.' Amanda Craig, New Statesman