This book brings together in one volume fifteen discoveries that have had a major impact upon medical science and the practice of medicine but where the scientists involved have not been awarded a Nobel Prize. Its aim is to publicize the achievements of these lesser-known heroes of our time and thereby inform and entertain the reader, whether medical student, professor or scientifically-minded layman. Contents:Archibald E Garrod: The Founding Father of Biochemical Genetics (David J Galton)Nikolai Anitschkow: The Birth of the Lipid Hypothesis of Atherosclerosis and Coronary Heart Disease (Daniel Steinberg)Willem-Karel Dicke: The Role of Gluten in Coeliac Disease (Chris J J Mulder and Karel A Dicke)Richard Doll: The Link Between Smoking and Lung Cancer (Tony Seed)Albert Sabin: The Development of an Oral Poliovirus Vaccine (Derek R Smith and Peter A Leggat)René Favaloro: Pioneer of Coronary Artery Surgery (Stephen Westaby)Christiaan Barnard and Norman Shumway: The Heart Transplant Pioneers (Stephen Westaby and David Marais)William Kouwenhoven and Paul Zoll: The Introduction of External Cardiac Massage, Defibrillators and Pacemakers (Max Lab)Inge Edler and Carl Hellmuth Hertz: The Development of Ultrasound for Clinical Use (Bhavna Batohi and Paul S Sidhu)Cyril Clarke, Ronald Finn, John Gorman, Vincent Freda and William Pollack: The Prevention of Rh Haemolytic Disease of the Newborn (David J Weatherall)Herbert Boyer and Stanley Cohen: Recombinant DNA (Anne Soutar)Harvey Alter and Michael Houghton: The Discovery of Hepatitis C and the Introduction of Screening to Prevent Its Transmission in Transfused Blood (Leonard B Seeff and Marc G Ghany)Willem Kolff and Belding Scribner: The Development of Renal Haemodialysis (John Turney)James Till and Ernest Mcculloch: The Discovery of Stem Cells (Joe Sornberger)Akira Endo: The Discovery of Statins (Gilbert Thompson and Hiroshi Mabuchi) Readership: Medical students, professionals and general public. Key Features:This book is the sequel to Nobel Prizes that Changed Medicine. Many of the authors have personal knowledge of the scientists they write about and all are distinguished authorities in their own field. No other book has brought together the non-Nobel Prize-winning discoveries having the greatest influence upon the practice of Medicine, dating from the first description of inborn errors of metabolism by Garrod in 1908 to the discovery of statins, for which Endo received the Lasker Award in 2008Keywords:Inborn Errors;Metabolism;Lipid Hypothesis;Atherosclerosis;Gluten;Coeliac Disease;Smoking;Lung Cancer;Polio Vaccine;Coronary Angiography;Coronary Bypass Grafting;Cardiac Transplantation;Cardiac Massage;Defibrillator;Pace Maker;Ultrasound;Rh Disease;Gene Cloning;Hepatitis C;Haemodialysis;Stem-Cells;Statins

This book brings together in one volume fifteen Nobel Prize-winning discoveries that have had the greatest impact upon medical science and the practice of medicine during the 20th century and up to the present time. Its overall aim is to enlighten, entertain and stimulate. This is especially so for those who are involved in or contemplating a career in medical research. Anyone interested in the particulars of a specific award or Laureate can obtain detailed information on the topic by accessing the Nobel Foundation''s website. In contrast, this book aims to provide a less formal and more personal view of the science and scientists involved, by having prominent academics write a chapter each about a Nobel Prize-winning discovery in their own areas of interest and expertise.

Attributing Excellence in Medicine discusses the aura around the prestigious Nobel Prize in Physiology or Medicine. It analyzes the social processes and contingent factors leading to recognition and reputation in science and medicine. This volume will help the reader to better understand the dynamics of the attribution of excellence throughout the 20th century. Contributors are Massimiano Bucchi, Fabio De Sio, Jacalyn Duffin, Heiner Fangerau, Thorsten Halling, Nils Hansson, David S. Jones, Gustav Källstrand, Ulrich Koppitz, Pauline Mattsson, Katarina Nordqvist, Scott H. Podolsky, Thomas Schlich, and Sven Widmalm.

We are swamped with information and each day seems to bring new discoveries that must be considered. Never before in the history of science have so many scientists been as active as today. It has become a major problem for the expert just to keep up with the literature in his or her own field of research. Why, then, should experts and their poor students worry about the pioneers of microbiology, those half-forgotten scientists who a century ago devoted their lives to a new science that was on its way to revolutionizing medicine? With so many new facts and problems screaming for our attention, it is easy to lose sight of the long road that we have travelled in order to get to the point where we are now. Tracing the path of those who have gone before us will help us to see our own scientific goals and efforts in a more revealing perspective. The great figures who are at the center of interest in this book — Robert Koch, Emil von Behring, Paul Ehrlich and Elie Metchnikoff — were far from uncontroversial during their lifetimes. It is interesting to see how they were judged by their peers at the Karolinska Institutet when they were considered for the Nobel Prize. Pioneers of Microbiology and the Nobel Prize has been written in such a way that it can be enjoyed even without an extensive knowledge of microbiology and medicine. In fact, a considerable part of the book portrays the state of medicine during the middle of the 19th century, when bacteriology can be said to have made its debut on the medical scene. Contents:The Sites of DiseasesCellular PathologyThe New PhysiologyBankruptcy and a Gleam of HopeContagion Versus MiasmaThe Birth of MicrobiologyBacteriology and the Nemesis of SurgeryRobert KochEmil von BehringPaul EhrlichElie MetchnikoffNobel Prizes and Nobel Committees (1901, 1905 and 1908)In Defence of the Nobel Prize Readership: Microbiologists; medical researchers, undergraduates and graduate students in microbiology and the life sciences; general readers. Keywords:Microbiology;Medical History;Nobel Prize;Robert Koch;Emil von Behring;Paul Ehrlich;Elie MetchnikoffReviews:“… The four main sections of the book are each a gem of a portrait in the miniature. The treatment is balanced; not only human greatness but failings are presented, making the descriptions very human and informative … Ulf Lagerkvist provides interesting data and observations about the nominations and the studies conducted by various members of the Committee on the candidates.”István Hargittai Budapest University of Technology and Economics, Hungary “Lagerkvist has written an extremely informative and simple description of four giants in the field of microbiology. His easy-going style and a focus on the straightforward elements of the lives of the Nobelists make for a voyage of entertainment and education.”Sidney Altman Yale University, USA “It is an informative review of the notable achievements of four great figures in medicine whose researches have virtually been eclipsed by the rapid advances of the 20th century.”Paul Berg Stanford University Medical Center, USA “This timely book reminds us of the achievements and careers of the equally great scientific pioneers of a hundred years ago, who discovered most of the agents that cause major human diseases, and also revealed our main defence against infectious agents, the antibodies … The author provides fascinating insights into the deliberations which resulted in well deserved awards for several scientific pioneers. This is an insiders' view of the strategy for choosing the right candidates for Nobel prizes.”Tomas Lindahl Cancer Research UK London Research Institute “Just over 100 years ago, the first Nobel Prize in Physiology or Medicine was awarded. This book is an authoritative and entertaining account of four of the early winners. The life and work of Robert Koch, Emil von Behring, Paul Ehrlich and Elie Metchnikoff are closely examined in the light of contemporary scientific knowledge and ignorance. Politics appear to have had as much to do with their final acceptance as Nobel Prize winners as did their outstanding scientific achievements. Many full-page portraits add to the charm of this book. Members of the public wanting to learn more about the birth of microbiology will find this book invaluable. Trainee as well as experienced microbiologists and immunologists will also find much of interest. There should be a copy in the often neglected history section of all good microbiologists libraries.”Microbiology Today “The book supplies superior details about the research and the social climate leading to the discoveries and provides good insight into the intellect and personalities that make extraordinary scientific discoveries. The rationale for awarding Nobel prizes in science is also thoroughly discussed … For anybody interested in the history and process of science.”Choice “The initial chapters beautifully describe the evolution of the ideas that formed the basis not only of medical microbiology but also of physiology and pathology … This book provides a series of portraits in which not only the achievements but additionally the failings are described, and effectively conjures up the academic milieu of the time.”Notes and Records of The Royal Society

Discusses the Nobel Institution in detail, telling about the award and its beginnings, what it means to win a Nobel Prize, the fields in which it is presented, who judges and how the prize is awarded, and more.

Battling disease, championing new techniques, recommending necessary medications, and offering comfort and guidance to those in need are just some of the many responsibilities with which healers over time have been charged. Even as the field of medical science rapidly evolves, doctors, researchers, and other medical professionals serve as significant reminders of the human element that has sustained the craft of healing for millennia. Readers discover surveys of the lives of many of those who are persevered in their pioneering quest for new and improved ways to treat a variety of ailments and conditions.

Originally published in 1990, Nobel Laureates in Medicine or Physiology is a biographical reference work about the recipients of Nobel Prizes in Medicine or Physiology from 1901-1989. Each article is written by an accomplished historian of medicine or science. The book is designed to be accessible to students and general readers as well as to specialists in medical science and history. Each article combines personal and scientific biography, and each has an extensive biography to guide further reading and research.