Hayes’ Principles and Methods of Toxicology has long been established as a reliable reference to the concepts, methodologies, and assessments integral to toxicology. The new sixth edition has been revised and updated while maintaining the same high standards that have made this volume a benchmark resource in the field. With new authors and new chapters that address the advances and developments since the fifth edition, the book presents everything toxicologists and students need to know to understand hazards and mechanisms of toxicity, enabling them to better assess risk. The book begins with the four basic principles of toxicology—dose matters, people differ, everything transforms, and timing is crucial. The contributors discuss various agents of toxicity, including foodborne, solvents, crop protection chemicals, radiation, and plant and animal toxins. They examine various methods for defining and measuring toxicity in a host of areas, including genetics, carcinogenicity, toxicity in major body systems, and the environment. This new edition contains an expanded glossary reflecting significant changes in the field. New topics in this edition include: The importance of dose–response Systems toxicology Food safety The humane use and care of animals Neurotoxicology The comprehensive coverage and clear writing style make this volume an invaluable text for students and a one-stop reference for professionals.

Hayes’ Principles and Methods of Toxicology has long been established as a reliable and informative reference for the concepts, methodologies, and assessments integral to toxicology. The new edition contains updated and new chapters with the addition of new authors while maintaining the same high standards that have made this book a benchmark resource in the field. Key Features: The comprehensive yet concise coverage of various aspects of fundamental and applied toxicology makes this book a valuable resource for educators, students, and professionals. Questions provided at the end of each chapter allow readers to test their knowledge and understanding of the material covered. All chapters have been updated and over 60 new authors have been added to reflect the dynamic nature of toxicological sciences New topics in this edition include Safety Assessment of Cosmetics and Personal Care Products, The Importance of the Dose/Rate Response, Novel Approaches and Alternative Models, Epigenetic Toxicology, and an Expanded Glossary. The volume is divided into 4 major sections, addressing fundamental principles of toxicology (Section I. "Principles of Toxicology"), major classes of established chemical hazards (Section II. "Agents"), current methods used for the assessment of various endpoints indicative of chemical toxicity (Section III. "Methods"), as well as toxicology of specific target systems and organs (Section IV. "Organ- and System-Specific Toxicology"). This volume will be a valuable tool for the audience that wishes to broaden their understanding of hazards and mechanisms of toxicity and to stay on top of the emerging methods and concepts of the rapidly advancing field of toxicology and risk assessment.

Sataloff's Comprehensive Textbook of Otolaryngology: Head & Neck Surgery - Laryngology is part of a multi-volume textbook covering basic and clinical science across the entire field of otolaryngology. Volumes in the set include; otology, neurotology and skull-based surgery; rhinology, allergy and immunology; facial plastic and reconstructive surgery; head and neck surgery; and paediatric otolaryngology. The full set is enhanced by over 5000 full colour images and illustrations, spanning nearly 6000 pages, complete with a comprehensive index on DVD. Edited by Robert T Sataloff from Drexel University College of Medicine, Philadelphia, this volume includes contributions from internationally recognised experts in otolaryngology, ensuring authoritative content throughout. Sataloff's Comprehensive Textbook of Otolaryngology: Head & Neck Surgery – Laryngology is an indispensable, in-depth guide to the field for all otolaryngology practitioners. Key Points Textbook of laryngology, part of six-volume set covering the entire field of otolaryngology Volumes include otology/neurotology, rhinology, plastic surgery, head and neck surgery, and paediatric otolaryngology Over 5000 full colour images and illustrations across six volumes Edited by Robert T Sataloff, with contributions from internationally recognised otolaryngology experts

Get ready for some fun! Try these unusual knitting techniques for stitching sweaters. Start at one cuff and knit to the other cuff. Or start at the shoulders and knit down to the waist. Or knit diagonally from corner to corner. Or knit a cable that goes from cuff to cuff and pick up stitches to knit up and down along the cable.