Naturally Occurring Benzodiazepines
Title | Naturally Occurring Benzodiazepines PDF eBook |
Author | Ivan Izquierdo |
Publisher | CRC Press |
Total Pages | 146 |
Release | 1993-01-01 |
Genre | Benzodiazepines |
ISBN | 9780130154880 |
An exploration of benzodiazepines (BZDs), including the widely-used drug Valium, which have been in wide circulation in clinical practice since the 1960s as sedatives, antidepressants, hypnotics and anticonvulsants. It reveals research results with naturally-occurring BZDs in plants and animals.
Naturally Occurring Benzodiazepines, Endozepines, and their Receptors
Title | Naturally Occurring Benzodiazepines, Endozepines, and their Receptors PDF eBook |
Author | Robert B. Raffa |
Publisher | CRC Press |
Total Pages | 215 |
Release | 2021-08-12 |
Genre | Medical |
ISBN | 1000421252 |
Discusses endogenous benzodiazepine-like substances – what do they do, do they affect the anti-anxiety drugs and their adverse effects? Presents information on the enigmatic prolonged benzodiazepine withdrawal syndrome Describes the compounds acting at the BDZ binding sites, both exogenous (classical BDZ drugs and BDZ from food and plants) and endogenous (endozepines) Assesses the putative interactions in physiology, pathology and pharmacology of the compounds acting at the BDZ binding sites
Naturally Occurring Benzodiazepines, Endozepines, and their Receptors
Title | Naturally Occurring Benzodiazepines, Endozepines, and their Receptors PDF eBook |
Author | Robert B. Raffa |
Publisher | CRC Press |
Total Pages | 216 |
Release | 2021-08-13 |
Genre | Medical |
ISBN | 1000421279 |
Understanding and addressing the current opioid crisis requires knowledge of endogenous opioids (endorphins and enkephalins), but there is now evidence for a benzodiazepine crisis. Are there endogenous benzodiazepine-like substances—and what do they do? How do they affect antianxiety drugs and their adverse effects? Do they explain enigmatic prolonged benzodiazepine withdrawal syndrome? This book raises important questions about the clinical consequences of ignoring the existence of or understanding the potential influence of endogenous benzodiazepines on the therapeutic effect of benzodiazepines, their adverse effects, and the problems of withdrawal from them and other benzodiazepine receptor agonists. FEATURES Discusses endogenous benzodiazepine-like substances—what do they do, and do they affect antianxiety drugs and their adverse effects? Presents information on enigmatic prolonged benzodiazepine withdrawal syndrome Describes the compounds acting at the BDZ binding sites, both exogenous (classical BDZ drugs and BDZ from food and plants) and endogenous (endozepines) Assesses the putative interactions in physiology, pathology, and pharmacology of the compounds acting at the BDZ binding sites Dr. Raffa is Adjunct Professor at the University of Arizona College of Pharmacy and Professor Emeritus at Temple University School of Pharmacy. He has co-authored or edited several books on pharmacology and thermodynamics, is a co-editor of two journals, is a past president of the Mid-Atlantic Pharmacology Society, and is the recipient of research and teaching awards. Dr. Amantea is Associate Professor of Pharmacology at the Department of Pharmacy, Health and Nutritional Sciences of the University of Calabria (Italy), where she is the leader of the Stroke Research Unit at the Section of Preclinical and Translational Pharmacology operating in the frame of the Italian Stroke Organization (ISO) Basic Science. She is a member of the Editorial Board and the Guest Editor of the 2016 Neuroscience section of Current Opinion in Pharmacology (Elsevier), and the founder and the editor of the CRC Press Frontiers in Neurotherapeutics series.
The Alkaloids: Chemistry and Pharmacology
Title | The Alkaloids: Chemistry and Pharmacology PDF eBook |
Author | |
Publisher | Academic Press |
Total Pages | 377 |
Release | 1991-01-10 |
Genre | Science |
ISBN | 0080865631 |
The Alkaloids: Chemistry and Pharmacology
Molecular Aspects of Anticancer Drug DNA Interactions
Title | Molecular Aspects of Anticancer Drug DNA Interactions PDF eBook |
Author | Stephen Neidle |
Publisher | CRC Press |
Total Pages | 386 |
Release | 1994-05-03 |
Genre | Medical |
ISBN | 9780849377730 |
This cutting-edge book surveys the current knowledge on the mode of action of the major classes of DNA-interactive antitumor agents, providing information that could be crucial for the discovery of new therapeutic substances. It is an important reference for molecular biologists, cancer researchers, biochemists, biophysicists, and pharmacologists.
Naturally Occurring Organohalogen Compounds
Title | Naturally Occurring Organohalogen Compounds PDF eBook |
Author | A. Douglas Kinghorn |
Publisher | Springer Nature |
Total Pages | 553 |
Release | 2023-07-24 |
Genre | Science |
ISBN | 3031266293 |
The present volume is the third in a trilogy that documents naturally occurring organohalogen compounds, bringing the total number — from fewer than 25 in 1968 — to approximately 8,000 compounds to date. Nearly all of these natural products contain chlorine or bromine, with a few containing iodine and, fewer still, fluorine. Produced by ubiquitous marine (algae, sponges, corals, bryozoa, nudibranchs, fungi, bacteria) and terrestrial organisms (plants, fungi, bacteria, insects, higher animals) and universal abiotic processes (volcanos, forest fires, geothermal events), organohalogens pervade the global ecosystem. Newly identified extraterrestrial sources are also documented. In addition to chemical structures, biological activity, biohalogenation, biodegradation, natural function, and future outlook are presented.
Naturally Occurring Organohalogen Compounds - A Comprehensive Update
Title | Naturally Occurring Organohalogen Compounds - A Comprehensive Update PDF eBook |
Author | Gordon W. Gribble |
Publisher | Springer Science & Business Media |
Total Pages | 622 |
Release | 2009-12-02 |
Genre | Science |
ISBN | 3211993231 |
Despite the long association of organohalogen compounds with human activities, nature is the producer of nearly 5,000 halogen-containing chemicals. Once dismissed as accidents of nature or isolation artifacts, organohalogen compounds represent an important and ever growing class of natural products, in many cases exhibiting exceptional biological activity. Since the last comprehensive review in 1996 (Vol. 68, this series), there have been discovered an additional 2,500 organochlorine, organobromine, and other organohalogen compounds. These natural organohalogens are biosynthesized by bacteria, fungi, lichen, plants, marine organisms of all types, insects, and higher animals including humans. These compounds are also formed abiogenically, as in volcanoes, forest fires, and other geothermal events.In some instances, natural organohalogens are precisely the same chemicals that man synthesizes for industrial use, and some of the quantities of these natural chemicals far exceed the quantities emitted by man.