This book constitutes the thoroughly refereed post-conference proceedings of the Third International Conference on Learning and Intelligent Optimization, LION 2009 III, held in Trento, Italy, in January 2009. The 15 revised full papers, one extended abstract and two poster sessions were carefully reviewed and selected from 86 submissions for inclusion in the book. The papers cover current issues of stochastic local search methods and meta-heuristics, hybridizations of constraint and mathematical programming with meta-heuristics, supervised, unsupervised and reinforcement learning applied to heuristic search, reactive search (online self-tuning methods), algorithm portfolios and off-line tuning methods, algorithms for dynamic, stochastic and multi-objective problems, interface(s) between discrete and continuous optimization, experimental analysis and modeling of algorithms, theoretical foundations, parallelization of optimization algorithms, memory-based optimization, prohibition-based methods (tabu search), memetic algorithms, evolutionary algorithms, dynamic local search, iterated local search, variable neighborhood search and swarm intelligence methods (ant colony optimization, particle swarm optimization etc.).

This volume constitutes the refereed proceedings of the International Workshop on Engineering Stochastic Local Search Algorithms. Inside the volume, readers will find twelve full papers as well as nine short papers. Topics include methodological developments, behavior of SLS algorithms, search space analysis, algorithm performance, tuning procedures, AI/OR techniques, and dynamic behavior.

This book constitutes the refereed proceedings of the International Workshop on Engineering Stochastic Local Search Algorithms 2009, held in Brussels, Belgium, September 3-5, 2009. The 7 revised full papers presented together with 10 short papers were carefully reviewed and selected from more than 27 submissions. The topics include e. g. the use of run time distributions to evaluate and compare, high- performance local search for task scheduling with human, running time analysis of ACO Systems for shortest path problems, the explorative behavior of MAX-MIN ant system and improved robustness through population variance and colony optimization.

Operations Research and Logistics are strongly connected: most of the theoretical developments of the former have been motivated by applications in the latter. The spirit of this special issue on Optimization Methods in Logistics moves along the same line, with methodological approaches presented to respond to the needs of practitioners. Applications emerging in different branches of the wide field of logistics have been addressed by authors from Belgium, Brazil, Singapore, Spain, Switzerland, Thailand and the USA.

This volume constitutes the refereed proceedings of the International Workshop on Engineering Stochastic Local Search Algorithms. Inside the volume, readers will find twelve full papers as well as nine short papers. Topics include methodological developments, behavior of SLS algorithms, search space analysis, algorithm performance, tuning procedures, AI/OR techniques, and dynamic behavior.

This book encapsulates and occupies recent advances and state-of-the-art applications of nature-inspired computing (NIC) techniques in the field of bioinformatics and computational biology, which would aid medical sciences in various clinical applications. This edited volume covers fundamental applications, scope, and future perspectives of NIC techniques in bioinformatics including genomic profiling, gene expression data classification, DNA computation, systems and network biology, solving personalized therapy complications, antimicrobial resistance in bacterial pathogens, and computer-aided drug design, discovery, and therapeutics. It also covers the role of NIC techniques in various diseases and disorders, including cancer detection and diagnosis, breast cancer, lung disorder detection, disease biomarkers, and potential therapeutics identifications.