At present, we do not fully understand at what stage of the evolution of living matter the first traces of defense reactions occurred. We even do not fully understand how and why immune systems reached their contem porary state in advanced vertebrates and man. It may be expected that in the near future these questions will be answered by comparative and develop mental biology. Together with an extraordinary explosion of our knowledge about immunity of mammals including man, an increase in the interests concerning origin and development of immune mechanisms at lower stages of the phylogeny can be observed. The search for simple types of immune mechanisms in less complex but still evolutionary successful animals is promising and may contribute to better understanding of highly complex immune adaptive responses in mammals. It is important to note that comparative and evolutionary immunology differs greatly from other branches of biomedical science. Apart from immunology and molecular biology, a specialist in this discipline has to be familiar with every detail of taxonomy, comparative anatomy, physiology, embryology, and even with the phyletic relationships of animals. Probably no monography could deal with the entire animal kingdom, because, in many cases, the insights into questions about immune mecha nisms of many animal groupings or phyla, and their possible evolutionary implications, are unknown or just now beginning to take shape. For the moment, our knowledge on such matters relies upon reconstructions of ideas that we have deduced from studies on members of relative taxa.

At present, we do not fully understand at what stage of the evolution of living matter the first traces of defense reactions occurred. We even do not fully understand how and why immune systems reached their contem porary state in advanced vertebrates and man. It may be expected that in the near future these questions will be answered by comparative and develop mental biology. Together with an extraordinary explosion of our knowledge about immunity of mammals including man, an increase in the interests concerning origin and development of immune mechanisms at lower stages of the phylogeny can be observed. The search for simple types of immune mechanisms in less complex but still evolutionary successful animals is promising and may contribute to better understanding of highly complex immune adaptive responses in mammals. It is important to note that comparative and evolutionary immunology differs greatly from other branches of biomedical science. Apart from immunology and molecular biology, a specialist in this discipline has to be familiar with every detail of taxonomy, comparative anatomy, physiology, embryology, and even with the phyletic relationships of animals. Probably no monography could deal with the entire animal kingdom, because, in many cases, the insights into questions about immune mecha nisms of many animal groupings or phyla, and their possible evolutionary implications, are unknown or just now beginning to take shape. For the moment, our knowledge on such matters relies upon reconstructions of ideas that we have deduced from studies on members of relative taxa.

The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Chemical Defenses of Arthropods charts the significant progress in the study of chemical defenses in arthropods, a rapidly expanding area of chemical ecology. The book groups the defensive compounds secreted by arthropods based on their main functionalities and sequentially lists them according to their carbon numbers. Organized into 19 chapters, this volume begins with an overview of the defensive exudates of arthropods and how arthropods have exploited these compounds to deter the ubiquitous and omnipresent predators around them. The next chapters introduce the reader to the defensive compounds produced in the exocrine glands of arthropods, ranging from alcohols and ketones to hydrocarbons, carboxylic acids, esters, 1,4-quinones and hydroquinones, lactones, phenols, steroids, and proteinaceous venoms. The book also discusses the taxonomic value of arthropod defensive compounds, with emphasis on factors affecting the composition of defensive secretions and taxonomic correlations that utilize them. Later chapters focus on arthropod biosynthesis of exocrine compounds, how insects tolerate the presence of plant toxins in their diets, and identified defensive compounds in arthropods. The book concludes with an analysis of the properties and characteristic distributions of arthropod natural products, along with their adaptiveness as defensive agents. This book is a valuable resource for biologists and chemists.

This book distills the essence of child psychoanalysis from the practice and thought of its founder Anna Freud, who for over 50 years has been at the forefront of this controversial field. Children are the most refractory of all subjects to treat analytically. Here, for the first time, is a primer on the difficult technique as practiced at the Hampstead Clinic in London, which was founded by Anna Freud and is today the leading child analytic center in the world. She and her colleagues expose their wealth of experience to systematic review, which yields up rich insights not only into child psychoanalysis and psychotherapy but also into basic child development. In addition, their findings have relevance to the understanding of emotional disturbance at all ages. The book follows the treatment situation through all its stages, from the first session to termination and follow-up. It focuses on the interaction between therapist and child in the treatment room, illustrating the points with copious clinical vignettes. One point examined is the structure of treatment with respect to such matters as scheduling sessions and handling interruptions. Another element that comes under scrutiny is the development of the child's relationship to the therapist, which subsumes such factors as establishing an alliance, transference, and resistance. The child's repertoire of expressions, both verbal and nonverbal, is explored, as is the therapist's armamentarium of interpretations and interventions. Woven throughout the description of these elements is incisive commentary by Anna Freud. Her commonsense approach gives the book unique value, lifting it to a rare level of human wisdom.