Tracing the pathology of early European encounters with Native peoples of the Southeast, this work concludes that, while indigenous peoples suffered from an array of ailments before contact, Natives had their most significant experience with new germs long after initial contacts in the sixteenth century.

There is no question that European colonization introduced smallpox, measles, and other infectious diseases to the Americas, causing considerable harm and death to indigenous peoples. But though these diseases were devastating, their impact has been widely exaggerated. Warfare, enslavement, land expropriation, removals, erasure of identity, and other factors undermined Native populations. These factors worked in a deadly cabal with germs to cause epidemics, exacerbate mortality, and curtail population recovery. Beyond Germs: Native Depopulation in North America challenges the “virgin soil” hypothesis that was used for decades to explain the decimation of the indigenous people of North America. This hypothesis argues that the massive depopulation of the New World was caused primarily by diseases brought by European colonists that infected Native populations lacking immunity to foreign pathogens. In Beyond Germs, contributors expertly argue that blaming germs lets Europeans off the hook for the enormous number of Native American deaths that occurred after 1492. Archaeologists, anthropologists, and historians come together in this cutting-edge volume to report a wide variety of other factors in the decline in the indigenous population, including genocide, forced labor, and population dislocation. These factors led to what the editors describe in their introduction as “systemic structural violence” on the Native populations of North America. While we may never know the full extent of Native depopulation during the colonial period because the evidence available for indigenous communities is notoriously slim and problematic, what is certain is that a generation of scholars has significantly overemphasized disease as the cause of depopulation and has downplayed the active role of Europeans in inciting wars, destroying livelihoods, and erasing identities.

A pathbreaking history of how participants in the slave trade influenced the growth and dissemination of medical knowledge As the slave trade brought Europeans, Africans, and Americans into contact, diseases were traded along with human lives. Manuel Barcia examines the battle waged against disease, where traders fought against loss of profits while enslaved Africans fought for survival. Although efforts to control disease and stop epidemics from spreading brought little success, the medical knowledge generated by people on both sides of the conflict contributed to momentous change in the medical cultures of the Atlantic world.

NATIONAL BOOK AWARD FINALIST | WINNER OF THE BANCROFT PRIZE. A landmark history—the sweeping story of the enslavement of tens of thousands of Indians across America, from the time of the conquistadors up to the early twentieth century. Since the time of Columbus, Indian slavery was illegal in much of the American continent. Yet, as Andrés Reséndez illuminates in his myth-shattering The Other Slavery, it was practiced for centuries as an open secret. There was no abolitionist movement to protect the tens of thousands of Natives who were kidnapped and enslaved by the conquistadors. Reséndez builds the incisive case that it was mass slavery—more than epidemics—that decimated Indian populations across North America. Through riveting new evidence, including testimonies of courageous priests, rapacious merchants, and Indian captives, The Other Slavery reveals nothing less than a key missing piece of American history. For over two centuries we have fought over, abolished, and tried to come to grips with African American slavery. It is time for the West to confront an entirely separate, equally devastating enslavement we have long failed truly to see. “The Other Slavery is nothing short of an epic recalibration of American history, one that’s long overdue...In addition to his skills as a historian and an investigator, Résendez is a skilled storyteller with a truly remarkable subject. This is historical nonfiction at its most important and most necessary.” — Literary Hub, 20 Best Works of Nonfiction of the Decade ““One of the most profound contributions to North American history.”—Los Angeles Times

A sweeping global history that looks beyond European urban centers to show how slavery, colonialism, and war propelled the development of modern medicine. Most stories of medical progress come with ready-made heroes. John Snow traced the origins of LondonÕs 1854 cholera outbreak to a water pump, leading to the birth of epidemiology. Florence NightingaleÕs contributions to the care of soldiers in the Crimean War revolutionized medical hygiene, transforming hospitals from crucibles of infection to sanctuaries of recuperation. Yet histories of individual innovators ignore many key sources of medical knowledge, especially when it comes to the science of infectious disease. Reexamining the foundations of modern medicine, Jim Downs shows that the study of infectious disease depended crucially on the unrecognized contributions of nonconsenting subjectsÑconscripted soldiers, enslaved people, and subjects of empire. Plantations, slave ships, and battlefields were the laboratories in which physicians came to understand the spread of disease. Military doctors learned about the importance of air quality by monitoring Africans confined to the bottom of slave ships. Statisticians charted cholera outbreaks by surveilling Muslims in British-dominated territories returning from their annual pilgrimage. The field hospitals of the Crimean War and the US Civil War were carefully observed experiments in disease transmission. The scientific knowledge derived from discarding and exploiting human life is now the basis of our ability to protect humanity from epidemics. Boldly argued and eye-opening, Maladies of Empire gives a full account of the true price of medical progress.

Introduction: A rising necropolis -- Patriotic fever -- Danse macabre -- Immunocapital -- Public health, private acclimation -- Denial, delusion, and disunion -- Incumbent arrogance -- Epilogue: Fever and folly.

How smallpox, or Variola, caused widespread devastation during the European colonization of the Americas is a well-known story. But as historian Paul Kelton informs us, that’s precisely what it is: a convenient story. In Cherokee Medicine, Colonial Germs Kelton challenges the “virgin soil thesis,” or the widely held belief that Natives’ lack of immunities and their inept healers were responsible for their downfall. Eschewing the metaphors and hyperbole routinely associated with the impact of smallpox, he firmly shifts the focus to the root cause of indigenous suffering and depopulation—colonialism writ large; not disease. Kelton’s account begins with the long, false dawn between 1518 and the mid-seventeenth century, when sporadic encounters with Europeans did little to bring Cherokees into the wider circulation of guns, goods, and germs that had begun to transform Native worlds. By the 1690s English-inspired slave raids had triggered a massive smallpox epidemic that struck the Cherokees for the first time. Through the eighteenth century, Cherokees repeatedly responded to real and threatened epidemics—and they did so effectively by drawing on their own medicine. Yet they also faced terribly destructive physical violence from the British during the Anglo-Cherokee War (1759–1761) and from American militias during the Revolutionary War. Having suffered much more from the scourge of war than from smallpox, the Cherokee population rebounded during the nineteenth century and, without abandoning Native medical practices and beliefs, Cherokees took part in the nascent global effort to eradicate Variola by embracing vaccination. A far more complex and nuanced history of Variola among American Indians emerges from these pages, one that privileges the lived experiences of the Cherokees over the story of their supposedly ill-equipped immune systems and counterproductive responses. Cherokee Medicine, Colonial Germs shows us how Europeans and their American descendants have obscured the past with the stories they left behind, and how these stories have perpetuated a simplistic understanding of colonialism.