Based on extensive participant observation research, a life-history model is presented to explain why very few of those who come into contact with narcotics become problematic consumers; that is make drugs one of the most central elements in their lives. The model covers four stages in the deviant career; two preceding and two subsequent to the individual's narcotics debut. Prohibition and harm reduction as models for intervention are presented, and the implications for drug policy of the life-history model are discussed.

With Demystifying Drug Dosing in Obese Patients, that resource you need is here, delivering: Fully-referenced dosing recommendations for specific drugs Dedicated chapters on antimicrobial dosing, anticoagulants and antiplatelets, antiepileptics, analgesics, antineoplastic medicines, and more Guidance on immunosuppression and medication absorption in bariatric surgery Tips for adult, pediatric, ambulatory, acute, and critical care Pharmacokinetic parameters in obese patients

Chronic kidney disease affects approximately 10% of adults in the United States or approximately 20 million individuals. Further, recent studies have shown that improper dosing in patients with renal dysfunction occurs over 20% of the time. ASHP’s Demystifying Drug Dosing in Renal Dysfunction addresses the persistent and challenging problem of dosing medications for patients with renal insufficiency and dysfunction.

Praised by practitioners, students and instructors for its engaging approach to teaching a very complex subject, Demystifying Opioid Conversion Calculations: A Guide for Effective Dosing, has long been the go-to guide for learning how to calculate opioid conversions. Now in its second edition, this reference is a must-have for clinicians involved in pain management at all levels. Written by pain management expert Mary Lynn McPherson, PharmD, MA, MDE, BCPS, CPE, Demystifying Opioid Conversion Calculations focuses on the calculations that practitioners use in actual practice, providing realistic scenarios for decision making. The revised edition covers the entire spectrum of opioid analgesics used to manage patients with moderate-to-severe pain and serious life­-limiting illnesses.

The Science and Business of Drug Discovery is written for those who want to learn about the biopharmaceutical industry and its products whatever their level of technical knowledge. Its aim is to demystify the jargon used in drug development, but in a way that avoids over simplification and the resulting loss of key information. Each of the nineteen chapters is illustrated with figures and tables which clarify some of the more technical points being made. Also included is a drug discovery case history which draws the relevant material together into a single chapter. In recognizing that it is difficult to navigate through the many external resources dealing with drug development, the book has been written to guide the reader towards the most appropriate information sources, including those listed in the two appendices. The following topics are covered: Different types of drugs: from small molecules to stem cells Background to chemistry of small and large molecules Historical background to drug discovery, pharmacology and biotechnology The drug discovery pipeline: from target discovery to marketed medicine Commercial aspects of drug discovery Challenges to the biopharmaceutical industry and its responses Material of specific interest to technology transfer executives, recruiters and pharmaceutical translators.

A creature of Jewish mythology, a golem is an animated being made by man from clay and water who knows neither his own strength nor the extent of his ignorance. Like science and technology, the subjects of Harry Collins and Trevor Pinch's previous volumes, medicine is also a golem, and this Dr. Golem should not be blamed for its mistakes - they ...

Searching for the ultimate stimulant? Something you can have on the bus in the morning or in the ambient comfort of your own home? The latest User's Guide - a totally natural and controlled experience - is just what you've been looking for. It contains everything you always wanted to know about drugs but were afraid to ask: The history of recreational drugs, a catalogue of natural highs and pharmaceuticals, the physiological effects, drugs and religion, drugs and the law, drug customs from around the world, trafficking drugs, drugs in literature, film and art, famous drug takers, drug slang, urban myths, drug legends and horror stories, quotations, tales of outrageous behaviour and a kilo of curious facts and figures. Did you know that- --Scientists have found traces of marijuana among Shakespeare's personal effects--Victorian prime minister Lord Rosebery would snort cocaine to help pep up his public speaking