This issue of Dermatologic Clinics, guest edited by Dr. John J. DiGiovanna, is devoted to Skin Science Contributions in Clinical Dermatology. Articles in this issue include Mosaic mTORopathies; CYLD: Cause and Therapeutic Target for Cylindromas; Current Status of Dedicator of Cytokinesis (DOCK), DOCK8, DOCK2; IL-22 relation to Tumor Aggression and Role of Cyclosporine; Dual Lineage of Dermal Fibroblasts and Potential for Scar Correction, Reformation of Adnexal Structures; Inflammasome Instigated Autoinflammatory Disorders; Pigment Cell Biology; Antimicrobial Peptides; and Choosing Friend or Foe? Commensal-specific tolerance.

This issue of Dermatologic Clinics, Guest Edited by Dr. Murad Alam, is devoted to Practice Gaps in Dermatology. Articles in this issue include: Psoriasis and Papulosquamous Disorders; Blistering Diseases; Disorders of the Nails; Disorders of the Hair; Infections; Abnormal Pigmentation; Lupus, Scleroderma, Dermatomyositis; Genodermatoses; Pruritus; Drug Reactions; Dermatoses of Pregnancy; Contact Dermatitis; Acne and Rosacea; Radiation Therapy; Surgery for Skin Cancer; Cosmetic Dermatologic Surgery; Light, Laser and Energy Treatments; and Melanocytic Lesions and Melanoma.

This issue of Dermatologic Clinics, guest edited by Jane M. Grant-Kels, Giovanni Pellacani, and Caterina Longo, is devoted to Confocal Microscopy. Articles in this timely issue include: Basics of Confocal Microscopy and the Complexity of Diagnosing Skin Tumors: New Imaging Tools in Clinical Practice, Diagnostic Workflows, Cost-estimate and New Trends; Opening a Window Into Living Tissue: Histopathologic Features of Confocal Microscopic Findings in Skin Tumors; Addressing the Issue of Discriminating Nevi from Early Melanomas: Dues and Pitfalls; Melanoma Types and Melanoma Progression: The Different Faces; Lentigo Maligna, Macules of the Face and Lesions on Sun-damaged Skin: Confocal makes the Difference; Glowing in the dark: use of confocal microscopy in dark pigmented lesions; Enlightening the Pink: Use of Confocal Microscopy in Pink Lesions; Shining into the White: The Spectrum of Epithelial Tumors from Actinic Keratosis to SCC; Application of Wide-probe and Handy-probe for Skin Cancer Diagnosis: Pros and Cons; Confocal Microscopy for Special Sites and Special Uses; Confocal Algorithms for Inflammatory Skin Diseases and Hair Diseases; In Vivo and Ex Vivo Confocal Microscopy for Dermatologic and Mohs’ Surgeons; Telediagnosis with Confocal Microscopy: A Reality or a Dream?; “Well-aging": Early Detection of Skin Aging Signs; The Role of Confocal Microscopy in Clinical Trials for Treatment Monitoring; and Fluorescence (multiwave) Confocal Microscopy.

This issue of Dermatologic Clinics, guest edited by John E. Harris, MD, PhD, is devoted to Vitiligo. Articles in this timely issue include: History of Vitiligo Management; Quality of Life/Burden of Disease; Comorbidities/Systemic Effects; Skin Cancer Risk (NMSC/Melanoma); Presentations, Signs of Activity, Differential Diagnosis; Segmental Vitiligo; Chemical-Induced Vitiligo; Medical Therapy and Maintenance of Vitiligo; Phototherapy and Combination Therapies for Vitiligo; Surgical Therapy; Depigmentation Therapy; Special Considerations in Children with Vitiligo; Role of Diet and Supplements in Vitiligo Management; Genetics; Pathogenesis and Emerging Treatments; and Repigmentation/Melanocyte Regeneration in Vitiligo.

This issue of Dermatologic Clinics, guested edited by Drs.Jonathan I. Silverberg and Nanette Silverberg, is devoted to Atopic Dermatitis. Articles in this outstanding issue include: How to Define Atopic Dermatitis; Public Health Burden and Epidemiology of Atopic Dermatitis; Long-term Course of Atopic Dermatitis; Allergic and Non-Allergic Comorbidities of Atopic Dermatitis; Patient-burden of Atopic Dermatitis; Assessment of Atopic Dermatitis Severity in Clinical Practice; An Update on the Pathophysiology of Atopic Dermatitis; Long-term Treatment of Atopic Dermatitis; Special Considerations for Management of Atopic Dermatitis in Young Children; Management of Adult Onset Atopic Dermatitis; Management of Atopic Hand Dermatitis; Adjunctive Management of Itch in Atopic Dermatitis; and Racial and Ethnic Differences of Atopic Dermatitis.

This issue of Dermatologic Clinics, guest edited by Drs. Darrell S. Rigel and Aaron S. Farberg, is devoted to Non-Invasive Technologies for the Diagnosis of Skin Cancer. Articles in this issue include: Current state and issues of clinical inspection; Tele-dermatology applications in skin cancer diagnosis; Enhancing skin cancer diagnosis with dermoscopy; Mole Mapping for management of pigmented skin lesions; Temporal image comparison (Serial Imaging) in assessing pigmented lesions; Multispectral digital skin lesion imaging and analysis; Using reflectance confocal microscopy in skin cancer diagnosis; Optical Coherence Tomography in the diagnosis of skin cancer; Electrical impedance spectroscopy in skin cancer diagnosis; The use of Raman Spectroscopy to detect and diagnose skin cancer; Applying high frequency ultrasound in the diagnosis of skin cancer; Proteomic mass spectrometery imaging for skin cancer diagnosis; Assessing skin cancer using epidermal genetic information retrieved by tape stripping; Smartphone-based applications for skin monitoring and melanoma detection; Detection of aberrations in cellular DNA in diagnosis and assessment of skin cancer; Assessing genetic expression profiles in melanoma diagnosis; Assessing genetic expression profiles in melanoma prognosis; and Integrating skin cancer related technologies into clinical practice.