On 25 December 2003, Union des Transport A riens de Guin e Flight GIH 141, a Boeing 727-223, on a flight from Conakry (Guinea) to Kufra (Libya), Beirut (Lebanon) and Dubai (United Arab Emirates) stopped over at Cotonou, Republic of Benin. During takeoff the overloaded airplane, was not able to climb properly and struck an airport building on the extended runway centerline, and crashed onto the beach and ended up in the ocean, killing 151 of the 163 people on board. The cause of the accident was the difficulty for the flight crew to rotate with an overloaded airplane with an unknown center of gravity. This in combination with the facts that the operator of the airline lacked any competence regarding organization and regulatory documentation, which made it impossible to correctly load and check the loading of the airplane, and the inadequacy of the supervision exercised by the Guinean civil aviation authorities in the context of safety oversight.

During the night of 04th May 2007, the B737-800, registration 5Y-KYA, operated by Kenya Airways as flight KQA 507 from Abidjan international airport (C te d'Ivoire), to the Jomo Kenyatta airport Nairobi (Kenya), made a scheduled stop-over at the Douala international airport (Cameroon). The weather was stormy. A number of departing planes decided to wait for the weather to improve. Kenya Airways, however, decided to depart. Shortly after take-off at about 1000 ft, the aircraft entered into a slow right roll that increased continuously and eventually ended up in a spiral dive. On the 5th May 2007 at approximately 0008 hrs, the airplane crashed in a mangrove swamp South-South/East of Douala. All 114 people on board were killed and the airplane was completely destroyed. The airplane crashed after loss of control by the crew as a result of spatial disorientation, after a long slow roll, during which no instrument scanning was done, and in the absence of external visual references in a dark night.

On 17 July 2007, at 17:19 local time, an Airbus A-320, operated as flight JJ3054 by TAM Linhas Aéreas, was on its way from Porto Alegre, Brazil, for a domestic flight to Congonhas Airport in São Paulo city, São Paulo State, Brazil. During the landing, at 18:54 local time, the aircraft veered to the left, overran the left edge of the runway, collided with a building, and with a fuel service station. All persons on board - six crewmembers, and 181 passengers - perished. The crash also caused 12 fatalities on the ground. The runway had recently been resurfaced, but it did not yet have water-channeling grooves cut into it to reduce the danger of hydroplaning, making landing during rain a dangerous endeavour. Flight Data Recorder information showed that immediately prior to touchdown, both thrust levers were in CL (or "climb") position, with engine power being governed by the flight computer's autothrottle system.

On 31 May 2009, the Airbus A330 flight AF 447 took off from Rio de Janeiro Gale o airport bound for Paris Charles de Gaulle. At around 2 h 02, the Captain left the cockpit for a short nap. At around 2 h 08, at flight level 350, the crew made a course change of 12 degrees to the left, to avoid bad weather. At 2h 10min 05, likely following the obstruction of the Pitot probes by ice crystals, the speed indications were incorrect and some automatic systems disconnected. The aeroplane's flight path was not controlled by the two copilots. They were rejoined 1 minute 30 later by the Captain, while the aeroplane was in a stall situation that lasted until the impact with the sea at 2 h 14 min 28 s, killing all 228 persons on board. It took almost two years to recover the wreck of the aircraft from a depth of 4.000 metres. The accident resulted from a succession of events, such as inconsistency between the measured airspeeds, inappropriate control inputs, and the crew's failure to diagnose the stall situation

On 25 January 2010, at 00:41:30 UTC, Ethiopian Airlines flight ET 409, a Boeing 737-800, on its way from Beirut to Addis Abeba, crashed just after take-off from Rafic Hariri International Airport in Beirut, Lebanon, into the Mediterranean Sea about 5 NM South West of Beirut International Airport. All 90 persons on board were killed in the accident. The investigation concluded that the probable causes of the accident were pilot errors due to loss of situational awareness. Ethiopian Airlines refutes this conclusion. Other factors that could have lead to probable causes are the increased workload and stress levels that have most likely led to the captain reaching a situation of loss of situational awareness similar to a subtle incapacitation and the F/O failure to recognize it or to intervene accordingly. Ethiopian Airlines refutes the investigation. According to the airline the final report was biased, lacking evidence, incomplete and did not present the full account of the accident.

On 2 May 2006 Armavia Flight RNV 967, an Airbus A320, was on its way from Zvartnots (Yerevan, Armenia) to Adler (Sochi, Russia). There were 113 occupants on board: 105 passengers (including 5 children and 1 baby), 2 pilots,1 aircraft engineer and 5 flight attendants. Upon approaching Sochi there was confusion in regard to the weather for the scheduled landing. Finally the captain decided to return to Zvartnots, a short while later he reconsidered his decision and started the approach to Sochi after all. Just before final landing air traffic control told the captain to abort the landing. At 22:13 the aircraft struck the water, it broke up on impact, killing all aboard. The investigation concluded that the crash of Armavia Flight 967 was a Controlled Flight Into Terrain (CFIT), specifically water, while conducting a climbing manoeuvre, after an aborted approach, along with inadequate control inputs from the Captain to Sochi airport at night with weather conditions below landing minimums for runway 06.

The Lockheed 1011 registered A6-BSM, operated by Star Jet and chartered by Olympic Airlines, arrived on 4 July 2005 at Terminal 1 at Paris Charles de Gaulle airport. Departure was delayed because the forward hold door could not be closed. A mechanic tried to close the door manually with a hammer and a chuck. Some passengers, worried about the apparent state of the cabin and the noise, asked to disembark, and this led to a mass movement. The airplane took finally off at 16h17. Shortly after departure the crew noticed problems with engine number 3. The captain requested the SEVERE DAMAGE procedure and returned to the airport. The French Bureau d'Enqu tes et d'Analyses pour la s curit de l'aviation civile (BEA) investigated the incident. BEA found out that the aircraft suffered from many problems, such as leaking fuel, malfunctioning safety features and lacking maintenance. The flight crew was not properly licensed, the captain was too old to fly in Europe. The Lockheed Tristar was a flying coffin.