This book is about the roles and importance of Ultraviolet (UV) light from sun and from man-made UV lamps in our daily life, on health and diseases, also its application in sterilization and treatment. The key words are: reactive oxygen species, DNA damage, UV mutagenicity, skin cancers, polymorphous light eruption, Xeroderma pigmentosum, vitiligo, psoriasis, rheumatoid arthritis, diabetes mellitus, metabolic syndromes, cardiovascular diseases, dermatology, photobiology, photodermatosis, vitamin D synthesis, vitamin D efficiency, water sterilization, blood sterilization, phototherapies, skin tanning and UV dosimeter. The book starts with introduction to UV light and the history of development of UV lamps and its applications. It then moves to describing the interaction of this light with biological components and the production of reactive oxygen species, their roles in cell signaling, cellular defense from foreign invaders, in mutagenesis leading to skin diseases including vitiligo, polymorphous light eruption and various forms of skin cancer. Then it presents the synthesis and importance of UV light and diseases, induced due to the deficiency of vitamin D. Roles of UV light in sterilization, disinfection, phototherapies are depicted in the next part and finally use and abuse of UV light in tanning salon and the availability and importance of use of UV dosimeter are highlighted. The three main focuses of this book are: - Damage to biological systems by UV light leading to certain skin diseases; most importantly skin cancers. - Importance of UV light in the in vivo synthesis of vitamin D when human bodies are exposed to it. - Diseases caused due to the deficiency of vitamin D and the use of UV lamps in phototherapy and sterilization processes. The editor has considerable experience in publishing medical books and has used it critically selecting the matters which will attract the readers from many areas of medical and non-medical fields. It is hoped that the materials presented in this book will give great benefit and will stimulate both novice and expert researchers in the field. The book gives excellent overviews of the current status of research and pointers to the future research achievements. Clinicians, medical general practitioners, technicians and staff working in UV related industries and especially those working in tanning salon should benefit from the information presented in safe handling of this light.

This report represents the views and expert opinions of an IARC Working Group that met in Lyon, France, 27-29 June 2005

This publication, prepared jointly by the WHO, the World Meteorological Organization and the United Nations Environment Programme, considers the public health challenges arising from global climate change and options for policy responses, with particular focus on the health sector. Aspects discussed include: an overview of historical developments and recent scientific assessments; weather and climate change; population vulnerability and the adaptive capacity of public health systems; the IPCC Third Assessment report; tasks for public health scientists; the health impacts of climate extremes; climate change, infectious diseases and the level of disease burdens; ozone depletion, ultraviolet radiation and health; and methodological issues in monitoring health effects of climate change.

This volume originates from the NATO Advanced Study Institute Environmental UV Radiation: Impact on Ecosystems and Human Health and Predictive Models, held in Pisa, Italy in June 2001. The Institute was sponsored and mainly funded by the NATO Scientific Affairs Division, whose constant contribution in favour of the cooperation among scientists from different countries must be acknowledged. Other Institutions substantially contributed to the success of the ASI and our thanks and appreciation go to the Italian National Research Council (Consiglio Nazionale delle Ricerche), the Italian Space Agency (Agenzia Spaziale Italiana), the European Society for Photobiology and the bank Banca Toscana. In the last two decades of the past century, concern has been growing for the possible effects on the biosphere of the stratospheric ozone depletion, due to anthropogenic emissions of ozone-destroying chemicals. The ozone loss causes an increase in the biologically important part of the solar ultraviolet radiation (UV) reaching the Earth’s surface, which constitutes a threat to the biosphere, because of UV damaging effects on humans, animals and plants. The international agreements have reduced the production of ozo- destroying compounds, which, however, are still present in high concentrations in the stratosphere, mainly because of their longevity, and thus ozone depletion will likely continue for several decades.