This book offers a comprehensive guide to thyroid fine needle aspiration (FNA) cytology. Borderline/precursor tumors, which were introduced in the 4th edition of the WHO classification of thyroid tumors, are also incorporated. In this second edition, prominent international experts discuss the different approaches to thyroid FNA cytology employed in various countries such as Australia, Canada, China, Korea, Portugal, Switzerland, Taiwan, Thailand, Turkey, Ukraine, the USA, UK, Italy and Japan. The book not only covers key principles of thyroid cytopathology but also addresses technical aspects such as procedural complications, liquid-based cytology, immunocytochemistry, staining procedures, and potential pitfalls. Case-based descriptions and clinical findings, radiologic imaging, cytology, and histopathologic diagnosis – all complemented by a wealth of detailed photographs – will help reader understand and overcome many common dilemmas in daily practice. As such, the book represents an indispensable reference work for all cytopathologists, especially those practicing thyroid cytopathology.

This atlas is the offspring of the “The National Cancer Institute (NCI) Thyroid Fine Needle Aspiration (FNA) State of the Science Conference,” hosted by the NCI and organized by Dr. Andrea Abati. Preparations for the conference began 18 months earlier with the designation of a steering committee and the establishment of a dedicated, p- manent web site. The meeting took place on October 22 and 23, 2007 in Bethesda, Maryland and was co-moderated by Susan J. Mandel and Edmund S. Cibas. The discussions and conclusions regarding terminology and morphologic criteria 1, 2 from the meeting were summarized in publications by Baloch et al. and form the framework for this atlas. The atlas is organized by the general categories of “Nondiagnostic,” “Benign,” “Follicular Neoplasm/Suspicious for a Follicular Neoplasm”, “Suspicious for Malignancy,” and “Malignant,” and it includes the defi- tions and morphologic criteria of these categories as set forth by Baloch et al. The majority of the conference participants also agreed on a category of “undetermined significance,” which is incorporated in this atlas (Chap. 4). It is critical that the cytopathologist communicate thyroid FNA interpretations to the referring physician in terms that are succinct, unambiguous, and helpful clinically. We recognize that the terminology used here is a flexible framework that can be modified by individual laboratories to meet the needs of their providers and the patients they serve.

This practical text and color atlas tells the story of 350 patients, covering a wide range of thyroid lesions with high quality composite images that correlate cytology with histology, and radiology with pathology. Each case includes clinical presentation and final pathology. Concise, easy-to-read text enables readers to quickly find the information they need for accurate diagnosis. 'Lookalike' lesions are grouped together so the subtle cytological differences can be appreciated. The author's practical approach explains mistakes made and lessons learned, so diagnostic pitfalls can be avoided. Triage algorithms and over 2000 printed photomicrographs are provided. The print book is accompanied by a CD-ROM offering images in downloadable format. Written by a leading cytopathologist who has performed onsite assessment for over 10,000 ultrasound-guided thyroid fine needle aspirations, this is an important resource for all healthcare professionals dealing with thyroid patients, including cytopathologists, surgical pathologists, cytotechnologists, sonographers, radiologists, endocrinologists and surgeons.

Successfully diagnose the full spectrum of thyroid neoplasia with Thyroid Cytopathology: A Text and Atlas! In this trusted pathology reference, readers are provided with the most comprehensive, authoritative coverage on the evaluation of thyroid fine-needle biopsy specimens available in one source. The text discusses everything from basic cytopathology concepts, fine-needle aspiration biopsy techniques, and cytopreparation through the interpretation of the complete range of cytology findings, ancillary diagnostic techniques, and the application of pathology reports to management decisions. With Thyroid Cytopathology: A Text and Atlas, you can confidently identify even the most challenging specimens in a timely manner in order to optimize clinical response.

Cytology is a unique subspecialty in anatomic pathology, and plays a critical role in the diagnosis of a variety of benign and malignant lesions by using minimally invasive procedures, such as fine needle aspiration, brushing, washing and lavage. Cytology not only provides an accurate diagnosis of the lesion based on the cytomorphological evaluation at cellular level, but also provides material for molecular characterization of a tumor for targeted therapy. In the era of personalized medicine, cytology has continued to grow and evolve as an important diagnostic tool. For example, some types of procedures are routinely used, diagnostic criteria have become more refined, and certain terminology has been changed based on current WHO classifications. Therefore, it is necessary to update our knowledge and terminology in cytology. In this volume, we have retained the quality and the clarity of the series, and like the other volumes, this volume aims to be concise and comprehensive yet clinically relevant to daily practice. Although this volume is written by multiple authors, all chapters follow a similar format: brief introduction of the specific organ/system (including types of specimens and techniques to obtain samples), description of normal findings, and a practice approach to diagnose benign and malignant lesions. In each chapter, the key cytomorphological feature and main differential diagnoses of the lesion are summarized in a concise table. Images in each chapter are instructive and clearly represent findings. Where necessary, we have also illustrated the important ancillary tests, such as flow cytometry, immunohistochemistry and molecular analysis, which are crucial for an accurate diagnosis and targeted therapy. The updated knowledge, including key cytomorphological features, current terminology and molecular diagnostic tests, is the highlight of this volume.

This updated edition remains the essential text for pathologists seeking to make accurate diagnoses from the vast number of differentials.

This illustrated volume serves as a handy guide to diagnostic fine needle aspiration (FNA) cytology of thyroid on liquid-based preparations (LBP). It is intended to be a ready resource to accurately diagnose thyroid lesions on LBP using key cytomorphologic features. Key cytologic differential diagnosis, gross, and histopathological correlations accompany the cytological findings. The Atlas of Thyroid Cytopathology on Liquid-Based Preparations is lavishly illustrated with color images of various thyroid diseases that should familiarize pathologists with the differences between conventional smears and LBP, and between the two commonly used LBPs. Authored by leaders in the field, this atlas provides clear, concise, and practical guidance pertaining to cytomorphology and the implications of thyroid FNA diagnoses for patient care in this era of precision medicine.