The field of planetary biology and chemical evolution draws together experts in astronomy, paleobiology, biochemistry, and space science who work together to understand the evolution of living systems. This field has made exciting discoveries that shed light on how organic compounds came together to form self-replicating molecules-the origin of life. This volume updates that progress and offers recommendations on research programs-including an ambitious effort centered on Mars-to advance the field over the next 10 to 15 years. The book presents a wide range of data and research results on these and other issues: The biogenic elements and their interaction in the interstellar clouds and in solar nebulae. Early planetary environments and the conditions that lead to the origin of life. The evolution of cellular and multicellular life. The search for life outside the solar system. This volume will become required reading for anyone involved in the search for life's beginnings-including exobiologists, geoscientists, planetary scientists, and U.S. space and science policymakers.

Life arose on Earth more than three billion years ago. How the first self-replicating systems emerged from prebiotic chemistry and evolved into primitive cell-like entities is an area of intense research, spanning molecular and cellular biology, organic chemistry, cosmology, geology, and atmospheric science. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology provides a comprehensive account of the environment of the early Earth and the mechanisms by which the organic molecules present may have self-assembled to form replicating material such as RNA and other polymers. The contributors examine the energetic requirements for this process and focus in particular on the essential role of semi-permeable compartments in containment of primitive genetic systems. Also covered in the book are new synthetic approaches for fabricating cellular systems, the potentially extraterrestrial origin of life's building blocks, and the possibility that life once existed on Mars. Comprising five sections Setting the Stage, Components of First Life, Primitive Systems, First Polymers, and Transition to a Microbial World it is a vital reference for all scientists interested in the origin of life on Earth and the likelihood that it has arisen on other planets

Origins of Life: A Cosmic Perspective presents an overview of the concepts, methods, and theories of astrobiology and origins of life research while presenting a summary of the latest findings. The book provides insight into the environments and processes that gave birth to life on our planet, which naturally informs our assessment of the probability that has arisen (or will arise) elsewhere. In addition, the book encourages readers to go beyond basic concepts, to explore topics in greater depth, and to engage in lively discussions. The text is intended to be suitable for mid- and upper-level undergraduates and beginning graduate students and more generally as an introduction and overview for researchers and general readers seeking to follow current developments in this interdisciplinary field. Readers are assumed to have a basic grounding in the relevant sciences, but prior specialized knowledge is not required. Each chapter concludes with a list of questions and discussion topics as well as suggestions for further reading. Some questions can be answered with reference to material in the text, but others require further reading and some have no known answers. The intention is to encourage readers to go beyond basic concepts, to explore topics in greater depth, and, in a classroom setting, to engage in lively discussions with class members.

The origin of life from non-life remains one of the most enduring mysteries of modern science. This book investigates how close scientists are to solving that mystery and explores what we are learning about the origin of life from current research in chemistry, physics, astrobiology, biochemistry, and more.

What is the origin of life? How did life begin? The question of life's origins has been asked for thousands of years and a variety of theories have been proposed. Yet, perhaps the right question has never been asked, which is, what does life do? To understand life, we must understand what it is, what it does, how it evolved from simple chemicals to self-replicating molecule, and then the questions of origins can be properly addressed. Did life begin in a deep sea thermal vent, or in an alkaline world? What were the role of viruses in kick starting life? Did life emerge from disequilibrium? What is the source of pre-genetic information? Did vesicles come first, or only after life had begun? In this text, over 20 of the world's leading scientists ask, and answer the hard questions, and in so doing may have ushered in a paradigm shift, and a scientific revolution in our understanding of the nature of life and its origins.

This volume contains the lectures presented at the second course of the International School of Space Chemistry held in Erice (Sicily) from October 20 - 30 1991 at the "E. Majorana Centre for Scientific Culture". The course was attended by 58 participants from 13 countries. The Chemistry of Life's Origins is well recognized as one of the most critical subjects of modem chemistry. Much progress has been made since the amazingly perceptive contributions by Oparin some 70 years ago when he first outlined a possible series of steps starting from simple molecules to basic building blocks and ultimate assembly into simple organisms capable of replicating, catalysis and evolution to higher organisms. The pioneering experiments of Stanley Miller demonstrated already forty years ago how easy it could have been to form the amino acids which are critical to living organisms. However we have since learned and are still learning a great deal more about the primitive conditions on earth which has led us to a rethinking of where and how the condition for prebiotic chemical processes occurred. We have also learned a great deal more about the molecular basis for life. For instance, the existence of DNA was just discovered forty years ago.