First published in 1966, THE CHEMISTRY OF LIFE has held its own as a clear and authoritative introduction to the world of biochemistry. This fourth edition has been fully updated and revised to include the latest developments in DNA and protein synthesis, cell regulation, and their social and medical implications.

This volume contains the lectures presented at the second course of the International School of Space Chemistry held in Erice (Sicily) from October 20 - 30 1991 at the "E. Majorana Centre for Scientific Culture". The course was attended by 58 participants from 13 countries. The Chemistry of Life's Origins is well recognized as one of the most critical subjects of modem chemistry. Much progress has been made since the amazingly perceptive contributions by Oparin some 70 years ago when he first outlined a possible series of steps starting from simple molecules to basic building blocks and ultimate assembly into simple organisms capable of replicating, catalysis and evolution to higher organisms. The pioneering experiments of Stanley Miller demonstrated already forty years ago how easy it could have been to form the amino acids which are critical to living organisms. However we have since learned and are still learning a great deal more about the primitive conditions on earth which has led us to a rethinking of where and how the condition for prebiotic chemical processes occurred. We have also learned a great deal more about the molecular basis for life. For instance, the existence of DNA was just discovered forty years ago.

Chemicals often have a negative Image among the general public. But there is no material world or indeed human beings without chemicals. The material world is operated by chemicals. The title ‘Chemicals for Life and Living’ implies that the material world is staged and played by chemicals. The book consists of five parts and an appendix. Part 1 – Essentials for life; Part 2 – Enhancing health; Part 3 – For the fun of life; Part 4 – Chemistry of the universe and earth, and Part 5 - Some negative effects of chemicals. The appendix gives a brief summary of what chemistry is all about, including a short chapter of chemical principles. No quantitative calculations are included in this book so that it is appealing for everyone – not just chemists.

The search for life in the solar system and beyond has to date been governed by a model based on what we know about life on Earth (terran life). Most of NASA's mission planning is focused on locations where liquid water is possible and emphasizes searches for structures that resemble cells in terran organisms. It is possible, however, that life exists that is based on chemical reactions that do not involve carbon compounds, that occurs in solvents other than water, or that involves oxidation-reduction reactions without oxygen gas. To assist NASA incorporate this possibility in its efforts to search for life, the NRC was asked to carry out a study to evaluate whether nonstandard biochemistry might support life in solar system and conceivable extrasolar environments, and to define areas to guide research in this area. This book presents an exploration of a limited set of hypothetical chemistries of life, a review of current knowledge concerning key questions or hypotheses about nonterran life, and suggestions for future research.

For anyone with a background in general chemistry.

This assembly of lectures should appeal to anyone with an interest in the history of science and the nature of living things. Seven of the eight lectures are by eminent biochemists and describe the development of their own subject 'from the inside; the eighth is a more general one.