For millennia, the Pantheon family have played a deadly chess game with humanity, willingly sacrificing innocent and guilty alike in their twisted pursuit of victory. But now, one member of the family sees the opportunity to end the eternal contest once and for all—a final, crushing triumph over his immortal siblings and all of human- and mutant-kind. The time has arrived for the Rat King to make his most chaotic and destructive moves yet. The time has come at last for… THE ARMAGEDDON GAME! Written by Tom Waltz and illustrated by Casey Maloney, Teenage Mutant Ninja Turtles Annual 2021 is the official prelude to the major TMNT event years in the making.

Prequel to the upcoming TMNT: Dimension X 5-week event this August! Krang was defeated by the Teenage Mutant Ninja Turtles and now awaits trial in Dimension X. Little do the Turtles know that Krang hired an assassin to destroy everyone who might testify against him, including themselves! This issue introduces a deadly and weird new villain, and begins the biggest Teenage Mutant Ninja Turtles adventure in space ever!

The Turtles embark on a secret mission to their roots, but a mysterious creature hunts them relentlessly. The Turtles will have to find a new way to come together to escape their foe—and the pain that haunts them. A special story of remembrance and family written and drawn by acclaimed artist Juni Ba!

The war is over. The Dragon is destroyed. The city is saved. But at what cost? Splinter is gone, the Turtles are in disarray, and the Shredder has returned. But all is not as it seems as the Turtles’ most-feared enemy struggles with this new opportunity to regain his honor. Meanwhile, a nearly decimated Foot Clan belongs to Karai, but can she truly rise to the task in the shadow of its greatest warrior? And how does a newly-changed Leatherhead fit into a post-mutation NYC?

A winner is crowned in Jennika's battle of the bands and two old foes make surprising revelations as the TMNT and allies prepare to take Mutant Town in a new direction! Important steps towards the next chapter of the TMNT saga are made here!

Leonardo stumbles across an underground fight ring in Mutant Town that caters to both humans and mutants. When Casey Jones convinces Leo to join in, he's startled to find that one of his opponents is someone of grave importance to him!

Raphael and Casey find themselves in the middle of a criminal caper gone awry that touches the lives of many of their friends... and enemies! Double-cross upon double-cross leads the Turtles to the heart of the NYC criminal underworld. Various factions jockey for power, but at the end of the day only one can end up on top. Will it be the Foot Clan? Expect the unexpected in this exciting, all-new Kevin Eastman-written/drawn tale!