Due to the fact that Restless Legs Syndrome/Willis-Ekbom Disease is usually a chronic condition, this book aims to provide physicians with the necessary tools for the long-term management of patients with RLS. The first part of the book addresses the various comorbidities and long-term consequences of RLS on life quality, sleep, cognitive, psychiatric and cardiovascular systems, while the second part focuses on the management of long-term treatment and the drug-induced complications in primary RLS and in special populations. Written by experts in the field, this practical resource offers a high-quality, long-term management of RLS for neurologists, sleep clinicians, pulmonologists and other healthcare professionals.

Do you feel an irresistible urge to move when you need to be still? Do you call the urges heebee jeebees, ants crawling under your skin, spider webs on your legs, electric feelings, growing pains, or crazy legs? If so, you may be an RLSer (a person who has Restless Legs Syndrome). If you want to be still through movies, long plane rides, hospital stays, or long days of working at your desk, read "Restless Legs Syndrome: The RLS Rebel's Survival Guide." You will learn to organize and develop effective ways to: Fight the "beast of RLS" Decrease the severity of your RLS Prevent RLS attacks Develop a Bag of Tricks Approach Develop team work with your doctor Help children who have RLS Communicate with RLS supporters.

Describes etiologies and pathophysiology of the condition, including secondary conditions and medications that can cause or accentuate RLS. Reveiws how to accurately diagnose RLS, nonpharmacologic measures, and details pharmacologic agents used to treat intermittent, daily, and refractory RLS.

Pharmacology of Restless Legs Syndrome (RLS), Volume 84, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field on essential topics, with this volume presenting chapters on Targeting the adenosinergic system in Restless Legs Syndrome, Assessing iron uptake mechanisms in the brain: impact of gender and genotype, Pharmacological treatments of RLS in augmentation, C. elegans and its applicability to studies on RLS, The neurophysiology of hyperarousal in RLS: hints for a role of glutamate/GABA, Treatment management and options in RLS patients, Pharmacological responsiveness of Periodic Legs Movements during Sleep, and more.

I feel very honoured to have been asked to write a brief foreword for this book on QRD-RLS Adaptive Filtering–asubjectwhichhas been close to my heart for many years. The book is well written and very timely – I look forward personally to seeing it in print. The editor is to be congratulated on assembling such a highly esteemed team of contributing authors able to span the broad range of topics and concepts which underpin this subject. In many respects, and for reasons well expounded by the authors, the LMS al- rithm has reigned supreme since its inception, as the algorithm of choice for prac- cal applications of adaptive ltering. However, as a result of the relentless advances in electronic technology, the demand for stable and ef cient RLS algorithms is growing rapidly – not just because the higher computational load is no longer such a serious barrier, but also because the technological pull has grown much stronger in the modern commercial world of 3G mobile communications, cognitive radio, high speed imagery, and so on.

Although briefly covered in neurology texts, until now there has been no professional-level publication dedicated solely to restless legs syndrome (RLS). Most of what is available is either out-of-date or too general. Written by a panel of experts, Restless Legs Syndrome fills the void. Focusing on diagnosis and management, the authors discuss the