In 1986, officials of the US Department of Energy revealed that the Hanford Atomic Products Operations in Richland, Washington, had been releasing radioactive material, in particular iodine-131, into the environment over a period of years. This information, which confirmed the suspicions of some people in the Pacific Northwest about what they called the Hanford Reservation or just Hanford, created quite a stir. Both the US Congress and citizens of the Northwest became keenly interested in knowing whether these radiation releases had caused human health effects. They were particularly concerned about whether Hanford releases of iodine-131 had led to an increase in thyroid disease among the population of the area. In 1988, Congress ordered a study of the human health effects of exposure to the iodine-131 released from Hanford. Funded by the Centers for Disease Control and Prevention (CDC), the study was carried out by the Seattle-based Fred Hutchinson Cancer Research Center over the last decade. The study examined estimate of exposure of the thyroid and rates of thyroid disease because iodine-131 concentrates in the thyroid and that organ would be the best indicator of radiation damage in the population. The Centers for Disease Control and Prevention (CDC) asked the National Academy of Sciences-National Research Council (NAS-NRC) to give an independent appraisal of the study methodology, results, and interpretation and of the communication of the study results to the public. Review of the Hanford Thyroid Disease Study Draft Final Report constitutes the response of the NRC subcommittee to that request. To respond to the charge, the NRC subcommittee felt that it needed to go beyond the specific questions addressed to it by CDC and develop a broad understanding and critique of the HTDS and the Draft Final Report. As part of those activities, the subcommittee solicited comments from outside experts and members of the public primarily in a public meeting held in Spokane, Washington, in June 1999, where 14 scientists and members of the public made formal presentations to the subcommittee about various aspects of the Draft Final Report. Other members of the public also spoke during four open-comment sessions at the meeting. In addition, efforts were made to evaluate all information materials prepared for the public and additional CDC communication plans. Information was gathered through interviews with journalists, members of concerned citizen groups in the Hanford region, members of the CDC scientific and media staff in Atlanta, and the HTDS investigators. In this summary, the main points follow the structure of our report and are presented under several headings: epidemiologic and clinical methods and data collection, dosimetry, statistical analyses, statistical power and interpretation of the study, and communication of the study results to the public. We then provide a brief synopsis of our response to the questions raised by CDC.

In 1986, officials of the US Department of Energy revealed that the Hanford Atomic Products Operations in Richland, Washington, had been releasing radioactive material, in particular iodine-131, into the environment over a period of years. This information, which confirmed the suspicions of some people in the Pacific Northwest about what they called the Hanford Reservation or just Hanford, created quite a stir. Both the US Congress and citizens of the Northwest became keenly interested in knowing whether these radiation releases had caused human health effects. They were particularly concerned about whether Hanford releases of iodine-131 had led to an increase in thyroid disease among the population of the area. In 1988, Congress ordered a study of the human health effects of exposure to the iodine-131 released from Hanford. Funded by the Centers for Disease Control and Prevention (CDC), the study was carried out by the Seattle-based Fred Hutchinson Cancer Research Center over the last decade. The study examined estimate of exposure of the thyroid and rates of thyroid disease because iodine-131 concentrates in the thyroid and that organ would be the best indicator of radiation damage in the population. The Centers for Disease Control and Prevention (CDC) asked the National Academy of Sciences-National Research Council (NAS-NRC) to give an independent appraisal of the study methodology, results, and interpretation and of the communication of the study results to the public. Review of the Hanford Thyroid Disease Study Draft Final Report constitutes the response of the NRC subcommittee to that request. To respond to the charge, the NRC subcommittee felt that it needed to go beyond the specific questions addressed to it by CDC and develop a broad understanding and critique of the HTDS and the Draft Final Report. As part of those activities, the subcommittee solicited comments from outside experts and members of the public primarily in a public meeting held in Spokane, Washington, in June 1999, where 14 scientists and members of the public made formal presentations to the subcommittee about various aspects of the Draft Final Report. Other members of the public also spoke during four open-comment sessions at the meeting. In addition, efforts were made to evaluate all information materials prepared for the public and additional CDC communication plans. Information was gathered through interviews with journalists, members of concerned citizen groups in the Hanford region, members of the CDC scientific and media staff in Atlanta, and the HTDS investigators. In this summary, the main points follow the structure of our report and are presented under several headings: epidemiologic and clinical methods and data collection, dosimetry, statistical analyses, statistical power and interpretation of the study, and communication of the study results to the public. We then provide a brief synopsis of our response to the questions raised by CDC.

For more than four decades beginning in 1944, the Hanford nuclear weapons facility in southeastern Washington State secretly blanketed much of the Pacific Northwest with low-dose ionizing radiation, the byproduct of plutonium production. For those who lived in the vicinity, many of them families of Hanford workers, the consequences soon became apparent as rates of illness and death steadily climbed—despite repeated assurances from the Atomic Energy Commission that the facility posed no threat. Trisha T. Pritikin, who has battled a lifetime of debilitating illness to become a lawyer and advocate for her fellow “downwinders,” tells the devastating story of those who were harmed in Hanford’s wake and, seeking answers and justice, were subjected to yet more suffering. At the center of The Hanford Plaintiffs are the oral histories of twenty-four people who joined In re Hanford Nuclear Reservation Litigation, the class-action suit that sought recognition of, and recompense for, the grievous injury knowingly caused by Hanford. Radioactive contamination of American communities was not uncommon during the wartime Manhattan Project, nor during the Cold War nuclear buildup that followed. Pritikin interweaves the stories of people poisoned by Hanford with a parallel account of civilians downwind of the Nevada atomic test site, who suffer from identical radiogenic diseases. Against the heartrending details of personal illness and loss and, ultimately, persistence in the face of a legal system that protects the government on all fronts and at all costs, The Hanford Plaintiffs draws a damning picture of the failure of the US Congress and the Judiciary to defend the American public and to adequately redress a catastrophic wrong. Documenting the legal, medical, and human cost of one community’s struggle for justice, this book conveys in clear and urgent terms the damage done to ordinary Americans in the name of business, progress, and patriotism.

The U.S.A. s nuclear weapons program has exposed workers and the public to health hazards since World War II. In the 1980s and 1990s, federal health agencies responded to new revelations about these hazards by pouring millions of dollars into research on the health impacts of radiation. In Tortured Science: Health Studies, Ethics and Nuclear Weapons in the United States , community health activists and researchers reflect on the research program for addressing the health effects of nuclear weapons production at Hanford, WA, Rocky Flats, CO, Livermore Labs, CA, and Fernald, OH. The authors describe conflicts of interest, data suppression, technical inadequacies, and other examples of how researchers failed in their social responsibility to the affected human populations. The research program s health studies did not lead to any meaningful follow-up on the major health concerns of community members, nor have they helped communities seek reparations for high radiation exposures that may have contributed to thyroid, bone, lung and other diseases. In Tortured Science , several ethicists review these health research problems. Research ethics as a discipline seeks to protect individuals and groups, obtain approval from affected communities, mitigate potential research harms, and guard against vigilance, scientific contrivance, denial, and suppression of findings. Such protections were not adequately provided in the research program on the health effects of nuclear weapons production, as critiqued in the ethical reviews. This book compels us to develop a new ethical framework for scientific research on military-industrial and other sources of contamination. Intended Audience: Public health professionals; graduates/undergraduates in public health, community health, environmental studies, epidemiology, medical anthropology, public sociology, ethics/religious studies, and science policy; government health researchers at federal health agencies, centres for ethics and bioethics (private/academic), and community health organisations; community-based researchers and environmental organisations; nuclear weapons and peace organisations.

are new to this edition. The authors provide not only the The second edition of Thyroid Cancer: A Comp- most current review of their respective areas, but also their hensive Guide to Clinical Management marks the pub- own recommendations and approach. The reader is fo- cation of a markedly updated and expanded volume that warned that in many cases these approaches, albeit rooted covers all aspects of the etiology, pathogenesis, diag- sis, initial treatment, and long-term management of all in available data, may be empiric rather than based varieties of thyroid cancer. Like the first edition, it will upon clear-cut results of well-controlled clinical t- als. Nevertheless, controversial issues are examined serve as a valuable reference source for pathologists, and evidence-based recommendations are presented endocrine surgeons, endocrinologists, nuclear medicine when available. physicians, and oncologists. However, the biggest There are updated chapters on our current state change is that the second edition is significantly enlarged and expanded to encompass important and extensive of knowledge of the molecular changes in thyroid treatments of more topics related to nuclear medicine. cancer, molecular markers, and how targeted the- pies are being developed. New therapeutic trials of Nuclear medicine physicians and procedures play a key redifferentiation agents to restore the sodium iodide role in the management of thyroid cancer patients and in symporter when lacking and more traditional che- retrospect, a comprehensive discussion of topics related therapies are discussed, with referral sources listed for to that field was somewhat lacking in the first edition.

A family reels from the effects of WWII nuclear fallout, but this is far from the Japan of 1945. It's 2006 in Washington State, and the war just took another life. In this new release of WWII home-front historical fiction, a 12-year-old boy named Asher seems to make his dad furious no matter what he does. In hopes of getting his dad back to normal, whatever that is, he looks for a way to fix it all. But he soon finds that he’s bitten off more than he can chew, when he discovers clues suggesting his grandpa’s death may not have been as natural as he was led to believe. The secrets he uncovers might change everything, but what does a nuclear bomb from 60 years ago have to do with his grandpa and does it have something to do with why his dad hates the world? Asher, Mari, and their quirky little sisters team up to solve the mystery before Asher’s dad destroys the family. It doesn’t take long, though, for Asher to realize that trying to save someone else from their own despondency can end up putting your own health at risk. Through the support of Mari and their top secret spy sisters, Asher uncovers enraging revelations about his grandfather's death, but realizes, a little too late, that some mysteries are better left unsolved.