Preacher Jesse Custer continues his dark journey to find God, accompanied by his gun-toting girlfriend and Irish vampire buddy. In the continuing saga of the bizarre adventures of faithless Texas preacher Jesse Custer, Jesse, along with his girlfriend Tulip and their friend Cassidy, the Irish vampire, head down South in hopes of recovering from their encounter with the forces of the Grail. But during their planned down time Jesse must face off against an enraged Arseface, who seeks to avenge his father’s death, while Tulip deals with Cassidy’s startling declaration of love for her. Also includes a special story spotlighting the Saint of Killers and the story of Cassidy’s first and only encounter with his fellow vampires.

Reverend Jesse Custer, an old Texas minister who is joined with a spiritual entity called Genesis and wields the Word of God, revisits terrors of his childhood on his way to find God.

"Follows the Reverend Jesse Custer on his epic quest to track down an absent God and force him to answer for the sufferings of his creation"--from the publisher.

Writer Garth Ennis's violent, scabrous journey across America's religious landscape continues in this fifth volume. Preacher Jesse Custer's dark journey to find God, accompanied by his gun-toting girlfriend and Irish vampire buddy, continues as Jesse becomes the sheriff of a troubled Texas town. Then, he decides it's high time to renew his quest to find God and hold him accountable for all of his actions. But before he can continue down that path, he must reunite with his girlfriend, Tulip.

Written by Garth Ennis; Art by Steve Dillon and Glenn Fabry A new edition of the collection including PREACHER #51-58 and the one-shot PREACHER: TALL IN THE SADDLE. Following the events of the PREACHER: SALVATION collection, Jesse Custer wants to renew his quest to find God and hold him accountable for all of his actions. But before he can continue down that path, he must reunite with his girlfriend Tulip. In this edition, we look back and see how Jesse and Tulip first met as well as how she became so deadly proficient with a gun. Also, after making amends with his love, Jesse seeks revenge against his former friend and compatriot Cassidy for the things that the Irish vampire did to Tulip during the time that they both believed the Preacher to be dead.

Preacher Jesse Custer's dark journey to find God, accompanied by his gun-toting girlfriend and Irish vampire buddy, continues in this fourth volume.