The history of disease is the history of humankind: an interpretation of the world as seen through the extraordinary impact—political, demographic, ecological, and psychological—of disease on cultures. "A book of the first importance, a truly revolutionary work." —The New Yorker From the conquest of Mexico by smallpox as much as by the Spanish, to the bubonic plague in China, to the typhoid epidemic in Europe, Plagues and Peoples is "a brilliantly conceptualized and challenging achievement" (Kirkus Reviews). Upon its original publication, Plagues and Peoples was an immediate critical and popular success, offering a radically new interpretation of world history. With the identification of AIDS in the early 1980s, another chapter was added to this chronicle of events, which William McNeill explores in his introduction to this edition. Thought-provoking, well-researched, and compulsively readable, Plagues and Peoples is essential reading—that rare book that is as fascinating as it is scholarly, as intriguing as it is enlightening.

"Here, my previous edition of Viruses, Plagues, & History is updated to reflect both progress and disappointment since that publication. This edition describes newcomers to the range of human infections, specifically, plagues that play important roles in this 21st century. The first is Middle East Respiratory Syndrome (MERS), an infection related to Sudden Acute Respiratory Syndrome (SARS). SARS was the first new-found plague of this century. Zika virus, which is similar to yellow fever virus in being transmitted by mosquitos, is another of the recent scourges. Zika appearing for the first time in the Americas is associated with birth defects and a paralytic condition in adults. Lastly, illness due to hepatitis viruses were observed prominently during the second World War initially associated with blood transfusions and vaccine inoculations. Since then, hepatitis virus infections have afflicted millions of individuals, in some leading to an acute fulminating liver disease or more often to a life-long persistent infection. A subset of those infected has developed liver cancer. However, in a triumph of medical treatments for infectious diseases, pharmaceuticals have been developed whose use virtually eliminates such maladies. For example, Hepatitis C virus infection has been eliminated from almost all (>97%) of its victims. This incredible result was the by-product of basic research in virology as well as cell and molecular biology during which intelligent drugs were designed to block events in the hepatitis virus life-cycle"--

A sweeping germ’s-eye view of history from human origins to global pandemics Plagues upon the Earth is a monumental history of humans and their germs. Weaving together a grand narrative of global history with insights from cutting-edge genetics, Kyle Harper explains why humanity’s uniquely dangerous disease pool is rooted deep in our evolutionary past, and why its growth is accelerated by technological progress. He shows that the story of disease is entangled with the history of slavery, colonialism, and capitalism, and reveals the enduring effects of historical plagues in patterns of wealth, health, power, and inequality. He also tells the story of humanity’s escape from infectious disease—a triumph that makes life as we know it possible, yet destabilizes the environment and fosters new diseases. Panoramic in scope, Plagues upon the Earth traces the role of disease in the transition to farming, the spread of cities, the advance of transportation, and the stupendous increase in human population. Harper offers a new interpretation of humanity’s path to control over infectious disease—one where rising evolutionary threats constantly push back against human progress, and where the devastating effects of modernization contribute to the great divergence between societies. The book reminds us that human health is globally interdependent—and inseparable from the well-being of the planet itself. Putting the COVID-19 pandemic in perspective, Plagues upon the Earth tells the story of how we got here as a species, and it may help us decide where we want to go.

An account of the effects of disease on history.

During Medieval times, the Black Death wiped out one-fifth of the world's population. Four centuries later, in 1665, the plague returned with a vengeance, cutting a long and deadly swathe through the British Isles. In this title, the author focuses on Cambridge, where every death was a singular blow affecting the entire community.

Plagues in World History provides a concise, comparative world history of catastrophic infectious diseases, including plague, smallpox, tuberculosis, cholera, influenza, and AIDS. John Aberth considers not only their varied impact but also the many ways in which people have been able to influence diseases simply through their cultural attitudes. Our ability to alter disease, even without modern medical treatments, is even more crucial lesson now that AIDS, swine flu, multidrug-resistant tuberculosis, and other seemingly incurable illnesses have raged worldwide. The author's comparative analysis of how different societies have responded in the past to disease illuminates what cultural approaches have been and may continue to be most effective in combating the plagues of today.