Reports in the popular press about the increasing longevity of Americans and the aging of the baby boom generation are constant reminders that the American population is becoming older. Consequently, an issue of growing medical, health policy, and social concern is the appropriate and rational use of medications by the elderly. Although becoming older does not necessarily correlate with increasing illness, aging is associated with anatomical and physiological changes that affect how medications are metabolized by the body. Furthermore, aging is often related to an increased frequency of chronic illness (often combined with multiple health problems) and an increased use of medications. Thus, a better understanding of the absorption, distribution, metabolism, and excretion of drugs; of the physiologic responses to those medications; as well as of the interactions among multiple medications is crucial for improving the health of older people.

Part 1 covers absorption, metabolism and excretion of drugs, the extent of medication use by the elderly, the reasons for increased use of drugs, and the factors that increase adverse drug reactions. Part 2 discusses the pharmacokinetics and pharmacodynamics of drugs, with further explaination of the causes of adverse drug reactions in the elderly. Other topics include the underuse of medication and common drug-drug interactions.

A guide for doctors to quickly choose the right drugs in the right dose for the most important clinical problems in the elderly Prescribing medications for elderly patients is complex - this book gives clear advice on treatment regimes, drug interactions, adverse effects, and recommended dose changes Provides practical help with the problems that can arise in reaching an accurate diagnosis in the elderly, recommends clear treatment options, lists key drug interactions and side effects, and advises when to amend doses

Nearly 20 million nuclear medicine procedures are carried out each year in the United States alone to diagnose and treat cancers, cardiovascular disease, and certain neurological disorders. Many of the advancements in nuclear medicine have been the result of research investments made during the past 50 years where these procedures are now a routine part of clinical care. Although nuclear medicine plays an important role in biomedical research and disease management, its promise is only beginning to be realized. Advancing Nuclear Medicine Through Innovation highlights the exciting emerging opportunities in nuclear medicine, which include assessing the efficacy of new drugs in development, individualizing treatment to the patient, and understanding the biology of human diseases. Health care and pharmaceutical professionals will be most interested in this book's examination of the challenges the field faces and its recommendations for ways to reduce these impediments.

A Strategy for Assessing Science offers strategic advice on the perennial issue of assessing rates of progress in different scientific fields. It considers available knowledge about how science makes progress and examines a range of decision-making strategies for addressing key science policy concerns. These include avoiding undue conservatism that may arise from the influence of established disciplines; achieving rational, high-quality, accountable, and transparent decision processes; and establishing an appropriate balance of influence between scientific communities and agency science managers. A Strategy for Assessing Science identifies principles for setting priorities and specific recommendations for the context of behavioral and social research on aging.