This is the third book in a series presenting Nobel Prizes in the life sciences using the remarkably rich archives of nominations and reviews which are kept secret for 50 years after the awards have been made. The two previous books are Nobel Prizes and Life Sciences (2010) and Nobel Prizes and Nature's Surprises (2013). The present book discusses the prizes in physiology or medicine 1963–65. The 1963 prize recognized milestone discoveries in the field of neurosciences, the way electrical impulses are generated and spread in nerves. The impressive developments of insights into tantalizing brain functions, like consciousness and memory, is discussed in the perspective of prizes both before and after the 1963 prize. The prize in 1964 marked the advanced biochemical venture that led to a full understanding of the synthesis of cholesterol, a central molecule for providing flexibility of the membranes of the trillions of cell in our body. The importance of this molecule for the appearance of cardiovascular diseases and the possibilities to prevent them is presented in the light of other prizes earlier and later in this field. The 1965 prize recognized three impressive French intellectuals, Lwoff, Monod and Jacob. Their contributions allowed the full maturation of the initial phase of the emerging field of molecular biology. The comprehension of the information flow from DNA via RNA to proteins was the source of a revolution of life sciences and of medicine.

This book brings together in one volume fifteen Nobel Prize-winning discoveries that have had the greatest impact upon medical science and the practice of medicine during the 20th century and up to the present time. Its overall aim is to enlighten, entertain and stimulate. This is especially so for those who are involved in or contemplating a career in medical research. Anyone interested in the particulars of a specific award or Laureate can obtain detailed information on the topic by accessing the Nobel Foundation''s website. In contrast, this book aims to provide a less formal and more personal view of the science and scientists involved, by having prominent academics write a chapter each about a Nobel Prize-winning discovery in their own areas of interest and expertise.

Each year the Nobel Prizes in the natural sciences reveal amazing discoveries. New milestones in the relentless advance of science are identified. The growth of knowledge and its evolution can be researched in the Nobel archives where nominations are kept secret for 50 years after the awards have been made. They represent a treasure for real-time assessment of science. Norrby's earlier book, Nobel Prizes and Life Sciences (2010) examined the unique archival records until 1959. The present book takes us up to 1962, surveying a range of dazzling discoveries. All prizes in immunology are reviewed. Their impact on our capacity to control infectious diseases and transplant organs are highlighted. The Nobel year 1962 is exceptional in recognizing the most major advance in biology since Darwin in 1859 presented his theory of evolution. This was the dramatic discovery of the double-helix structure of DNA by Watson and Crick in 1953. The era of molecular biology had begun. Its explosive development continues into the present. Contents:A Magician of Virology from AustraliaA Divided Nobel Prize and a New Era in ImmunologyMore Nobel Prizes in ImmunologyImmunity, Infections and TransplantationsTransgressing Borders in Science and Scenes of LifeMaking Sense of HearingUnraveling the Complexity of Protein Folding“It's So Beautiful, You See, So Beautiful”Coda Readership: General. Keywords:DNA;Nobel Prize;Life Science;Medical Disoveries;Molecular BiologyReviews: "This book describes and explains one of the most important discoveries of the 20th century. It is a seminal work, that scholars of the History of Science will use to be able to understand how science evolves. Young scientists will find this book a valuable resource." Sir Aaron Klug Nobel laureate in Chemistry, 1982 "Speculation about what happens in the selection of Nobel Prize winners is part of both the narrative and the ‘gossip’ of science. Interpreting what went on in the Nobel selection committees 50 years ago requires both an intimate understanding of how the process works and familiarity with subtleties of the Swedish language. Erling Norrby has the proper personal experiences to make such evaluations. In the present, his second, book he mainly reviews Medical Nobel awards during 1960 and 1962. Coming as it does near the beginnings of the modern medicine — recognizing exceptional advances in immunology and molecular biology — this is a fascinating era for those who are intrigued by the history of discovery." Peter C Doherty Nobel laureate in Physiology or Medicine, 1996 "The moment the Nobel Foundation announces its Prizes in the sciences, decades of struggle and turmoil toward discovery enter the spotlight. To skillfully examine some of the most dramatic scientific advances in the middle of the twentieth century, Erling Norrby has reached deeply into the Nobel archives to examine firsthand how many of the most illustrious Prizes from that era came to be awarded. As a superb scientist, educator and administrator, Dr Norrby is able to tell these stories within the context of the scientific discoveries." Stanley B Prusiner Nobel laureate in Physiology or Medicine, 1997 “I particularly enjoyed Norrby's lengthy treatment of the 1962 chemistry prize — to James Watson, Francis Crick, and Maurice Wilkins, 1962 for their structural work on the structure of DNA … This well-referenced and copiously illustrated book, featuring meditations, poetry, quotations, and miscellaneous musings, is a true labour of love. I heartily recommend it to anyone interested in the history of scientific discovery, the personalities of those who pursue it, and how it actually happens and is received.” Chemistry & Industry

This book brings together in one volume fifteen discoveries that have had a major impact upon medical science and the practice of medicine but where the scientists involved have not been awarded a Nobel Prize. Its aim is to publicize the achievements of these lesser-known heroes of our time and thereby inform and entertain the reader, whether medical student, professor or scientifically-minded layman. Contents:Archibald E Garrod: The Founding Father of Biochemical Genetics (David J Galton)Nikolai Anitschkow: The Birth of the Lipid Hypothesis of Atherosclerosis and Coronary Heart Disease (Daniel Steinberg)Willem-Karel Dicke: The Role of Gluten in Coeliac Disease (Chris J J Mulder and Karel A Dicke)Richard Doll: The Link Between Smoking and Lung Cancer (Tony Seed)Albert Sabin: The Development of an Oral Poliovirus Vaccine (Derek R Smith and Peter A Leggat)René Favaloro: Pioneer of Coronary Artery Surgery (Stephen Westaby)Christiaan Barnard and Norman Shumway: The Heart Transplant Pioneers (Stephen Westaby and David Marais)William Kouwenhoven and Paul Zoll: The Introduction of External Cardiac Massage, Defibrillators and Pacemakers (Max Lab)Inge Edler and Carl Hellmuth Hertz: The Development of Ultrasound for Clinical Use (Bhavna Batohi and Paul S Sidhu)Cyril Clarke, Ronald Finn, John Gorman, Vincent Freda and William Pollack: The Prevention of Rh Haemolytic Disease of the Newborn (David J Weatherall)Herbert Boyer and Stanley Cohen: Recombinant DNA (Anne Soutar)Harvey Alter and Michael Houghton: The Discovery of Hepatitis C and the Introduction of Screening to Prevent Its Transmission in Transfused Blood (Leonard B Seeff and Marc G Ghany)Willem Kolff and Belding Scribner: The Development of Renal Haemodialysis (John Turney)James Till and Ernest Mcculloch: The Discovery of Stem Cells (Joe Sornberger)Akira Endo: The Discovery of Statins (Gilbert Thompson and Hiroshi Mabuchi) Readership: Medical students, professionals and general public. Key Features:This book is the sequel to Nobel Prizes that Changed Medicine. Many of the authors have personal knowledge of the scientists they write about and all are distinguished authorities in their own field. No other book has brought together the non-Nobel Prize-winning discoveries having the greatest influence upon the practice of Medicine, dating from the first description of inborn errors of metabolism by Garrod in 1908 to the discovery of statins, for which Endo received the Lasker Award in 2008Keywords:Inborn Errors;Metabolism;Lipid Hypothesis;Atherosclerosis;Gluten;Coeliac Disease;Smoking;Lung Cancer;Polio Vaccine;Coronary Angiography;Coronary Bypass Grafting;Cardiac Transplantation;Cardiac Massage;Defibrillator;Pace Maker;Ultrasound;Rh Disease;Gene Cloning;Hepatitis C;Haemodialysis;Stem-Cells;Statins

The Nobel Prizes m natural sciences have achieved the reputation of being the ultimate accolade for scientific achievements. This honk gives a unique insight into the selection of Nobel Prize recipients, in particular the life sciences. The evolving mechanisms of selection of prize recipients are illustrated by reference to archives, which have remained secret for 1) years. Many of the prizes subjected to particular evaluation concern awards given for discoveries in the field of infectious diseases and the interconnected field of genetics. The book illustrates the individuals and environments that are conducive to scientific creativity. Nowhere is this enigmatic activity'-- the mime mover in advancing the human condition highlighted as lucidly as by identification individuals worthy of Nobel Prizes. --Book Jacket.

Since 1901 there have been over three hundred recipients of the Nobel Prize in the sciences. Only ten of themâ€"about 3 percentâ€"have been women. Why? In this updated version of Nobel Prize Women in Science, Sharon Bertsch McGrayne explores the reasons for this astonishing disparity by examining the lives and achievements of fifteen women scientists who either won a Nobel Prize or played a crucial role in a Nobel Prize - winning project. The book reveals the relentless discrimination these women faced both as students and as researchers. Their success was due to the fact that they were passionately in love with science. The book begins with Marie Curie, the first woman to win the Nobel Prize in physics. Readers are then introduced to Christiane Nusslein-Volhard, Emmy Noether, Lise Meitner, Barbara McClintock, Chien-Shiung Wu, and Rosalind Franklin. These and other remarkable women portrayed here struggled against gender discrimination, raised families, and became political and religious leaders. They were mountain climbers, musicians, seamstresses, and gourmet cooks. Above all, they were strong, joyful women in love with discovery. Nobel Prize Women in Science is a startling and revealing look into the history of science and the critical and inspiring role that women have played in the drama of scientific progress.

Discusses the Nobel Institution in detail, telling about the award and its beginnings, what it means to win a Nobel Prize, the fields in which it is presented, who judges and how the prize is awarded, and more.