The multidisciplinary applications of natural science in drug discovery are essential for identifying and developing new drugs and represent a promising area of research. Drug discovery is a complex and challenging process that involves multiple disciplines, including biology, chemistry, pharmacology, and medicine. One of the most interesting areas of drug discovery is using natural science, which involves the study of natural products and their potential therapeutic benefits, in which the research literature has previously been lacking appropriate attention. Multidisciplinary Applications of Natural Science for Drug Discovery and Integrative Medicine is a research book that bridges the gap between traditional and natural science approaches to identify new drug molecules in treating various diseases. The book focuses on allopathic and complementary medicine. It takes a cross-disciplinary examination of biology, chemistry, pharmacology, mathematics, physics, and medicine. This book is suitable for researchers, post-doctoral fellows, graduate students, and post-graduate students interested in exploring natural science's multidisciplinary applications in drug discovery and integrative medicine.

Despite considerable technological advances, the pharmaceutical industry is experiencing a severe innovation deficit, especially in the discovery of new drugs. Innovative Approaches in Drug Discovery: Ethnopharmacology, Systems Biology and Holistic Targeting provides a critical review and analysis of health, disease and medicine, and explores possible reasons behind the present crisis in drug discovery. The authors illustrate the benefits of systems biology and pharmacogenomics approaches, and advocate the expansion from disease-centric discovery to person-centric therapeutics involving holistic, multi-target, whole systems approaches. This book lays a path for reigniting pharmaceutical innovation through a disciplined reemergence of pharmacognosy, embracing open innovation models and collaborative, trusted public-private partnerships. With unprecedented advances made in the development of biomedically-relevant tools and technologies, the need is great and the time is now for a renewed commitment towards expanding the repertoire of medicines. By incorporating real-life examples and state-of-the-art reviews, this book provides valuable insights into the discovery and development strategies for professionals, academicians, and students in the pharmaceutical sciences. Analyzes the reasons behind historical drug failures to provide valuable insights on lessons learned Uses current scientific research to promote learning from traditional knowledge systems and through the integration of traditional and western medicines Discusses advances in technologies and systems biology to support the transition from formulation discovery to therapeutic discovery

Active botanical ingredients are a prime requirement for herbal formulations and discovering a drug is all about integration of science disciplines. In recent decades there has been a growing interest in treating wounds and diseases using traditional remedies based on local herbs, combined with chemical advances. Although this has led to the development of new bioactive ingredients from plants, there has been little success in terms of clinical trials and post-marketing studies to comply with FDA guidelines. Plants have been used as a source of medicine throughout history and continue to serve as the basis for many pharmaceuticals used today. However, despite the modern pharmaceutical industry being founded on botanical medicine, synthetic approaches to drug discovery have now become standard. Science-driven translational discovery and botanical development has created a new reality, leading to enormous changes in strategies, technologies and the disciplines involved, which have been embraced by the pharmaceutical and biotech industries. This book gathers scientific expertise and traditional knowledge to promote the discovery and development of new formulations and drugs based on active ingredients and to provide guidance on taking these to clinical trials. It discusses major topics, such as how the phytochemical composition of many plants has changed over time due to factors like cultivation, which can have both positive and negative effects on the levels of bioactive compounds. It also explores the importance of plants as a valuable source of therapeutic compounds as a result of their vast biosynthetic capacity, and classifies them according to their intended use, safety and regulatory status. Further, the book offers insights into the regulatory aspects of botanical products, which is an important issue when considering standardization and quality assessment, and also examines the commercial aspects of plant-derived medications and their proven role in the treatment of chronic diseases such as heart disease, high blood pressure, pain, asthma, and other associated conditions. Given its scope, this book is a valuable tool for botanists, natural product chemists, pharmacologists and microbiologists involved in the study of phytochemicals for drug discovery.

Natural Products and Drug Discovery: An Integrated Approach provides an applied overview of the field, from traditional medicinal targets, to cutting-edge molecular techniques. Natural products have always been of key importance to drug discovery, but as modern techniques and technologies have allowed researchers to identify, isolate, extract and synthesize their active compounds in new ways, they are once again coming to the forefront of drug discovery. Combining the potential of traditional medicine with the refinement of modern chemical technology, the use of natural products as the basis for drugs can help in the development of more environmentally sound, economical, and effective drug discovery processes. Natural Products & Drug Discovery: An Integrated Approach reflects on the current changes in this field, giving context to the current shift and using supportive case studies to highlight the challenges and successes faced by researchers in integrating traditional medicinal sources with modern chemical technologies. It therefore acts as a useful reference to medicinal chemists, phytochemists, biochemists, pharma R&D professionals, and drug discovery students and researchers. Reviews the changing role of natural products in drug discovery, integrating traditional knowledge with modern molecular technologies Highlights the potential future role of natural products in preventative medicine Supported by real world case studies throughout

In the dynamic environment of healthcare, the fusion of Computational Intelligence and Healthcare Industry 4.0 has enabled remarkable advancements in disease detection and analysis. However, a critical challenge persists – the limitations of current computational intelligence approaches in dealing with small sample sizes. This setback hampers the performance of these innovative models, hindering their potential impact on medical applications. As we stand at the crossroads of technological innovation and healthcare evolution, the need for a solution becomes paramount. Advances in Computational Intelligence for the Healthcare Industry 4.0 is a comprehensive guide addressing the very heart of this challenge. Designed for academics, researchers, healthcare professionals, and stakeholders in Healthcare Industry 4.0, this book serves as a source of innovation. It not only illuminates the complexities of computational intelligence in healthcare but also provides a roadmap for overcoming the limitations posed by small sample sizes. From fundamental principles to innovative concepts, this book offers a holistic perspective, shaping the future of healthcare through the lens of computational intelligence and Healthcare Industry 4.0.

Cutting-Edge Applications of Nanomaterials in Biomedical Sciences is a comprehensive exploration of the revolutionary impact of nanotechnology on the field of medicine. This book delves into the remarkable potential of nanomaterials in advancing medical diagnostics and therapeutics, particularly in drug delivery. It serves as an indispensable guide, presenting the latest developments in nanomedicine, precision medicine, and nanoengineering while addressing the challenges and opportunities that arise. The book covers a wide range of topics, from nanomaterials for cancer therapy to their applications in imaging and diagnostics. It discusses the transformative role of nanomaterials in targeted delivery and controlled release, as well as their potential in regenerative medicine and infectious disease diagnosis and treatment. By presenting cutting-edge research and developments in the field, this book aims to bridge the gap between bench and bedside, providing a vital resource for researchers, clinicians, and students in the biomedical sciences. Moreover, it highlights the commercialization potential of nanomedicine, fostering collaboration between academia and industry. Policymakers and regulators will also find this book invaluable for understanding the ethical and safety implications of incorporating nanomaterials into medical practices.

In a world driven by technology and data, classical computing faces limitations in tackling complex challenges like climate modeling and financial risk assessment. These barriers impede our aspirations to revolutionize industries and solve intricate real-world problems. To bridge this gap, we must embrace quantum computing. Edited by Alex Khang PH, Principles and Applications of Quantum Computing is a transformative solution to this challenge. It delves into the interdisciplinary realms of computer science, physics, and mathematics, unveiling the incredible potential of quantum computing, which outperforms supercomputers by 158 million times. This technology, rooted in quantum mechanics, offers solutions to global problems and opens new frontiers in AI, cybersecurity, finance, drug development, and more. By engaging with this book, you become a pioneer in the quantum revolution, contributing to reshaping the limits of what's achievable in our digital age.