Describes individual genes and/or phenotypes representing individual genes.

Describes individual genes and/or phenotypes representing individual genes.

Morrison (human genetics, University of Ulster, UK) and Spence (biomedical science, University of Ulster, UK) offer an accessible reference on the genetic disorders that surgeons can expect to meet in general surgical practice. Written in non-technical language, with a glossary, list of abbreviations, and color and b&w photos and medical images, the book supplies an introduction to the nomenclature and technology of molecular biology, and will be a useful starting point for those who wish to extend their knowledge. Annotation :2005 Book News, Inc., Portland, OR (booknews.com).

Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.

Experiments which in previous years were made with ornamental plants have already afforded evidence that the hybrids, as a rule, are not exactly intermediate between the parental species. With some of the more striking characters, those, for instance, which relate to the form and size of the leaves, the pubescence of the several parts, etc., the intermediate, indeed, is nearly always to be seen; in other cases, however, one of the two parental characters is so preponderant that it is difficult, or quite impossible, to detect the other in the hybrid. from 4. The Forms of the Hybrid One of the most influential and important scientific works ever written, the 1865 paper Experiments in Plant Hybridisation was all but ignored in its day, and its author, Austrian priest and scientist GREGOR JOHANN MENDEL (18221884), died before seeing the dramatic long-term impact of his work, which was rediscovered at the turn of the 20th century and is now considered foundational to modern genetics. A simple, eloquent description of his 18561863 study of the inheritance of traits in pea plantsMendel analyzed 29,000 of themthis is essential reading for biology students and readers of science history. Cosimo presents this compact edition from the 1909 translation by British geneticist WILLIAM BATESON (18611926).

"The principal source of information on inherited diseases for all clinical geneticists... In addition to the erudite entries in the books, the references given with each description represent a magnificent bibliography of clinical genetics. With McKusick's leadership and continued interest in gene mapping, the book also represents an important compendium of the location of genes on specific chromosomes." -- New England Journal of Medicine.

Will revolutionize reader's understanding of the principles of modern genetics, Nazi racial policies and the relationship between them.