In this issue of Gastroenterology Clinics, guest editor Dr. Sunanda V. Kane brings her considerable expertise to the topic of Medical and Surgical Management of Crohn’s Disease. Approximately 3 million people worldwide suffer with Crohn’s Disease, and this issue provides a thorough review of current treatment and management strategies in various patient populations. Topics include fecal microbiota transplant, microbiome-targeting diet, anti-TNF therapy in pediatric IBD patients, and many more. Contains 13 practice-oriented topics including mimics of Crohn’s; newer therapies for Crohn’s disease; diet and nutrition in Crohn’s disease; pediatric management of Crohn’s disease; and more. Provides in-depth clinical reviews of medical and surgical management of Crohn’s disease, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Dr. Loftus is a widely recognized expert in the diagnosis and treatment of Crohn's disease. He has created an issue devoted the current state-of-the-art on Crohn's disease; authors have written comprehensive reviews on the latest research to inform clinical diagnosis and treatment. Articles are devoted to the following topics: Genetics; Epidemiology, natural history, and risk stratification of Crohn’s disease; The microbiome in Crohn’s disease: Role in pathogenesis and role of microbiome replacement therapies; Endoscopic and radiographic assessment of Crohn’s disease; Intestinal and non-intestinal cancer risk in Crohn’s disease; Sexuality, fertility, and pregnancy in Crohn’s disease; Interdisciplinary management of perianal Crohn’s disease; Targeting specific immunologic pathways in human inflammatory bowel disease; Evolution of treatment paradigms in Crohn’s disease; Preventing and managing postoperative recurrence of Crohn’s disease; Where and how to use anti-TNF agents and anti-integrins in Crohn’s disease; Ustekinumab and anti-interleukin-23 agents in Crohn’s disease; Update on therapeutic drug monitoring in Crohn’s disease; and Janus kinase antagonists and other novel small molecules for the treatment of Crohn’s disease. Readers will come away from this issue armed with the information they need to improve management of this disease as well as patient outcomes.

Together with Consulting Editor, Dr. Alan Buchman, Dr. Scott Lee has put together a state-of-the-art issue of Gastroenterology Clinics devoted to Ulcerative Colitis (UC). He has selected expert authors to contribute clinical reviews that provide the latest clinical findings and recommendations. Articles are devoted to the following topics: Epidemiology and pathogenesis of UC; Making initial diagnosis of UC and ruling out other diseases that mimic UC; Assessing severity of disease; Initial medical treatment of UC; Treatment of UC with steroids; Biologic therapy in UC; Non-biologic immune suppression in UC; Microbiome and fecal transplant in UC; Health maintenance in UC, including bone density scan, vaccination recommendations, cancer screening; Women's issues and UC; Risk of colon cancer and recommended surveillance strategies in UC patients; Surgical management of UC, indications and outcomes from colectomy; and Management of J-pouches. Readers will come away with the latest clinical recommendations they need to improve outcomes in patients with UC.

Inflammatory Bowel Disease is reviewed extensively in this important Surgical Clinics of North America issue. Articles include: Inflammatory Bowel Disease: Historical Perspective, Epidemiology and Risk Factors; Diagnostic Modalities for Inflammatory Bowel Disease: Serologic Markers and Endoscopy; Diagnostic Modalities for Inflammatory Bowel Disease: Radiologic Imaging; Medical Therapy for Inflammatory Bowel Disease; Crohn's Disease of the Foregut and Small Intestine; Crohn's Disease of the Colon, Rectum and Anus; Indications and Options for Surgery in Ulcerative Colitis; Challenges in the Medical and Surgical Management of Chronic Inflammatory Bowel Disease; Extraintestinal Manifestations of Inflammatory Bowel Disease; Colorectal Neoplasia and Inflammatory Bowel Disease; Nutritional Support of the Inflammatory Bowel Disease Patient; Psychosocial Support of the Inflammatory Bowel Disease Patient; Genetics and Pathogenesis of Inflammatory Bowel Disease; and more!

This issue of Surgical Clinics of North America focuses on Inflammatory Bowel Disease and is edited by Dr. Sean Langenfeld. Articles will include: IBD presentation and diagnosis; Endoscopy in IBD; Preoperative considerations in IBD; Postoperative Considerations in IBD; IBD and cancer/dysplasia; Elective abdominal surgery for IBD; Abdominal emergencies in IBD; Anorectal Crohn’s disease; Other surgeries in IBD patients; Pediatric inflammatory bowel disease; Pouch complications; Genetic and environmental considerations for IBD; IBD and short bowel syndrome; Medical Management of IBD; and more!

This issue will review the medical and surgical management of ulcerative colitis and Crohn's disease. Included within the issue will be articles devoted to the various debates surrounding different surgical techniques and long-term outcomes. Readers will benefit from discussions on the latest knowledge of the biology of IBD as well as emerging non-operative therapies.