THE authoritative guide for clinical laboratory immunology For over 40 years the Manual of Molecular and Clinical Laboratory Immunology has served as the premier guide for the clinical immunology laboratory. From basic serology testing to the present wide range of molecular analyses, the Manual has reflected the exponential growth in the field of immunology over the past decades. This eighth edition reflects the latest advances and developments in the diagnosis and treatment of patients with infectious and immune-mediated disorders. The Manual features detailed descriptions of general and specific methodologies, placing special focus on the interpretation of laboratory findings, and covers the immunology of infectious diseases, including specific pathogens, as well as the full range of autoimmune and immunodeficiency diseases, cancer, and transplantation. Written to guide the laboratory director, the Manual will also appeal to other laboratory scientists, especially those working in clinical immunology laboratories, and pathologists. It is also a useful reference for physicians, mid-level providers, medical students, and allied health students with an interest in the role that immunology plays in the clinical laboratory.

Reflects changes being thrust upon the laboratory community.

Introducing clinical immunology, this text offers detailed instruction in immunobiology, lab methods and clinical serology, and is divided into three sections, covering the whole scope of clinical immunology. Coverage includes: immune reactions by the human host in response to a challenge; fundamental mechanisms of the immune system; antigens and antibodies and their interaction in serologic testing; the principles of "in vitro" serologic reactions and the sources of error and quality control in testing; and immunologic diseases in which measurement of an immune product or reaction is a significant tool for diagnosing or monitoring the disease. Features new to this edition include: chapter outlines; learning objectives; colour plates; review questions; and case studies. New chapters highlight: nucleic acid probes and blotting techniques; spriochetal infection and serology; Burrelia Burgdorfei infections and serology; and transplantations.

A two-in-one text providing teaching lab students with an overview of immunology as well as a lab manual complete with current standard exercises. Section I of this book provides an overview of the immune system and immunity, and includes review questions, problem sets, case studies, inquiry-based questions, and more to provide students with a strong foundation in the field. Section II consists of twenty-two lab exercises focused on key concepts in immunology, such as antibody production, cell separation, cell function, immunoassays, Th1/Th2 cytokine detection, cell and tissue culture methods, and cell and molecular biology techniques. Appendices include safety information, suggested links and readings, and standard discipline processes, protocols, and instructions.