Luther's Works: The American Edition, published by Concordia and Fortress Press between 1955 and 1986, comprises fifty-five volumes. These are a selection representing only about a third of Luther's works in the Latin and German of the standard Weimar Edition, not including the German Bible. Luther treats Isaiah and his message as one still relevant for modern times, in fact for all time. The lesson is that God in Jesus Christ comes to the rescue of God's people in God's own good time, just as God did to the nation and government of the Jews in Isaiah's time. Meanwhile, God's people are to await God's help in complete confidence and not rely on self-help and on alliances with other men. The great danger then and now, however, lies in humankind's rebellion against God's way, for humankind is naturally impatient about waiting for God to do all things well. To God's invitation that humankind find strength "in quietness and in trust," humankind is always under temptation to respond: "No, we will speed upon horses!" Luther bids us learn from Isaiah that we are helped and protected by God as the people of Israel were and that we are also chastened like them when this is necessary. This volume contains lectures on Isaiah, chapters 1 through 39.

In discoursing on the second half of Isaiah, Luther seems especially concerned about students preparing for the ministry. His central theme, from chapter 40, "The Word of our God will stand forever," reappears again and again in his commentary, like a bell tolling its purpose. Luther probably felt the need to repeat this message first of all for his own comfort. He admits: "If I had known that the world was so puzzlingly evil, I would never have begun the task of preaching and writing." Concerning Isaiah's message he says, "These are words of consolation. Just hold tight, even if you are oppressed and persecuted and your thoughts and conscience trouble you." As his faith strengthens and solidifies, so Luther encourages his students to hold fast to the same by taking up the work of Christ and warning: "Beware that you do not neglect the Word. It indeed stands firm, but it moves and will be given to others.... Therefore let us prayerfully keep busy with the Word." This volume contains lectures on Isaiah, chapters 40 through 66. Also available in a set containing Volume 1 - 30 and Luther the Expositor.