This book describes the risks of working with dangerous pathogens and toxins in the current era of international terrorism. The authors characterize the global spread of legitimate biotechnology and relate it to the rise of transnational terrorism, emphasizing the need for biosecurity measures even in legitimate bioscience. This second edition is considerably longer than the first and includes several new chapters and sections, with the final two-thirds of the book entirely reorganized.

By achieving a delicate balance between systems and practices, proper laboratory biosecurity reduces the risk of legitimate bioscience facilities becoming sources of pathogens and toxins for malicious use. Effective design and implementation of laboratory biosecurity depends on cooperation among individuals from diverse communities, including scien

This is the third edition of this manual which contains updated practical guidance on biosafety techniques in laboratories at all levels. It is organised into nine sections and issues covered include: microbiological risk assessment; lab design and facilities; biosecurity concepts; safety equipment; contingency planning; disinfection and sterilisation; the transport of infectious substances; biosafety and the safe use of recombinant DNA technology; chemical, fire and electrical safety aspects; safety organisation and training programmes; and the safety checklist.

The Laboratory biosecurity guidance is a revision of the first edition of the WHO Biorisk management - Laboratory biosecurity guidance, 2006. As introduced in the 4th edition of the Laboratory biosafety manual (LBM4), the novel risk- and evidence-based approach is applied for biosecurity in this guidance. The guidance is intended to help researchers, biosafety/biosecurity officers and other laboratory personnel properly assess and manage risks inherent to high-consequence research. Furthermore, it contains a template for biosecurity risk assessment in the laboratory to prevent theft, misuse and unauthorized access to biological material, and also includes a two-tier approach for national oversight of biological risk management as well as a hybrid approach with risk- and list-based elements to regulate high-consequence material.

Over the past two decades bioscience facilities worldwide have experienced multiple safety and security incidents, including many notable incidents at so-called "sophisticated facilities" in North America and Western Europe. This demonstrates that a system based solely on biosafety levels and security regulations may not be sufficient. Setting the stage for a substantively different approach for managing the risks of working with biological agents in laboratories, Laboratory Biorisk Management: Biosafety and Biosecurity introduces the concept of biorisk management—a new paradigm that encompasses both laboratory biosafety and biosecurity. The book also provides laboratory managers and directors with the information and technical tools needed for its implementation. The basis for this new paradigm is a three-pronged, multi-disciplinary model of assessment, mitigation, and performance (the AMP model). The application of the methodologies, criteria, and guidance outlined in the book helps to reduce the risk of laboratories becoming the sources of infectious disease outbreaks. This is a valuable resource for those seeking to embrace and implement biorisk management systems in their facilities and operations, including the biological research, clinical diagnostic, and production/manufacturing communities.

This book is a concise guide to medical laboratory safety in hospitals. Divided into five sections, it covers biosafety and biosecurity, chemical hazards, radioactive materials hazards, healthcare-associated infections and biocides, and waste management. The manual describes methods to prevent accidents, as well as measures that should be taken if they do occur. Safety measures suggested by the World Health Organisation (WHO) and Centres for Disease Control (CDC) are also included. Manual of Laboratory Safety is an invaluable, up to date reference guide for laboratory owners and technicians and includes images, illustrations and tables, to enhance learning. Key points Concise guide to medical laboratory safety in hospitals Covers all hazards including chemical and radioactive hazards, infections and waste management Includes safety measures suggested by the WHO and CDC Features images, illustrations and tables to enhance learning