In Insulin Resistance: The Metabolic Syndrome X, outstanding investigators thoughtfully summarize our current understanding of how insulin resistance and its compensating hyperinsulinemia (Syndrome X) play a major role in the pathogenesis and clinical course of high blood pressure and cardiovascular disease-the so-called diseases of Western civilization-as well as polycystic ovary disease. Under the aegis of Gerald Reaven, the discoverer of Syndrome X, the distinguished authorities writing here detail for the first time the pathophysiological consequences and the clinical syndromes, excluding Type 2 diabetes, related to insulin resistance. They also examine the genetic and lifestyle factors that contribute to the wide differences in insulin action that exist in the population at large. Each author has been encouraged to present a point of view that reflects their unique insights. The first authoritative book on the subject, Insulin Resistance: The Metabolic Syndrome X illuminates the special importance of insulin resistance as a major cause of hypertension, heart disease, and polycystic ovary syndrome. Its thoughtful and detailed approach will make it an essential reference for basic and clinical researchers seeking to understand these critical phenomena.

Diabetes is now one of the major causes of morbidity worldwide. In many cases, the onset of diabetes is progressive, developing via a condition of insulin resistance. This book considers the development of this condition, its consequences and clinical and therapeutic aspects. The book reviews the normal biology of insulin action on glucose, lipids and proteins. It considers the pathological basis for insulin resistance in animal models and humans, and discusses the influence of heredity, dietary factors and exercise. Clinical consequences including dyslipidaemia, hypertension and polycystic ovary syndrome, and therapeutic strategies for treatment are also examined. * Provides an expert review of the phenomenon of insulin resistance * Brings together a host of recent research for the first time * Written by leading experts in biological and clinical research

Understanding Insulin and Insulin Resistance is written in a simple and clear language illustrated with diagrams that show the complex interplay of various factors in the initiation of insulin resistance. The design is systematic and meticulous, portraying topics in a flow from simple to complex. This resource is intended for a broad audience spanning across biochemistry, medicine, dentistry, academia, physicians, and research scholars. It extends the approach to biochemistry, physiology, metabolism of insulin along with the coverage of pathophysiology of insulin resistance, its effects on the body tissues, and its analysis on insulin resistance syndrome.

Now in a revised and expanded second edition, this unique text presents topics related to insulin resistance in youth and its consequences across the lifespan. In the first section of the book examining epidemiology, the contributors review controversies over the definition of insulin resistance in children and what is known about how insulin resistance in youth differs from adults, the measurement of insulin resistance in youth in the research and clinical settings, and current knowledge regarding the epidemiology of insulin resistance in the pediatric population. The second section of the book explores pathophysiology, including current knowledge of the molecular, metabolic, and physiologic mechanisms of insulin resistance, the unique pathophysiology of pregnancy and puberty, the contributions of the prenatal and early childhood environment to the development of insulin resistance, and adipose and biochemical mediators. This section concludes with discussion of the relationship between insulin resistance and cardiovascular disease and liver disorders. A third section, new to this second edition, explores insulin resistance in unique models: intrauterine growth restriction and girls with polycystic ovary syndrome and metabolic syndrome. The final section of the book explores the concepts of treatment through medications directed at insulin sensitivity, as well as exercise, weight loss medications and consequences of bariatric surgery. Insulin Resistance: Childhood Precursors of Adult Disease, Second Edition provides up-to-date reviews of all of these areas, providing the reader with a current perspective on issues in insulin resistance in youth, an emerging risk factor for disease across the lifespan, that will spur continued interest in the topic on the part of clinicians and researchers, perhaps promoting new points of view and creative approaches to this daunting challenge.

Insulin resistance, commonly known as Syndrome X, affects a staggering 1 in 5 people. It is characterized by the over-production of insulin and is the underlying cause of many serious health problems, including heart disease, type II diabetes, obesity, high blood pressure, and deep vein thrombosis. The Insulin Resistance Factor offers a unique nutritional plan to reverse the effects of insulin resistance through diet, exercise, and nutritional supplements. Experienced nutritionist Antony J. Haynes shows how to: Determine your level of insulin resistanceUnderstand the key nutrients, antioxidants, and foods that can reverse insulin resistancePrepare simple and delicious meals that won’t leave you hungryLower your risk of heart disease and cancerImprove your memory and concentrationLower your cholesterol and high blood pressureSlow the aging process For anyone who struggles with weight, lethargy, high blood pressure, or high cholesterol The Insulin Resistance Factor offers a solution.

Help your body naturally reverse insulin resistance using delicious food. Whether you're dealing with diabetes, PCOS, or just looking to manage an erratic metabolism, the insulin resistance diet can be key to a very satisfying, healthy lifestyle. Break the monotonous boundaries of managing your insulin response with The Insulin Resistance Diet for Beginners. This complete lifestyle guide will help your body naturally regulate glucose and insulin levels while putting creative, delicious, and diverse meals on the table. Relatable analogies, food humor, and realistic recipes make it fun to understand how the insulin resistance diet and lifestyle can change not only your metabolism, but your entire life outlook. The included shopping guides and meal plans make it easy to start your new lifestyle right away. The path to steady glucose levels and a strong metabolism begins in the kitchen--here's your guide to the insulin resistance diet. Inside The Insulin Resistance Diet for Beginners you'll find: Roadmap for success--A five-step plan makes the insulin resistance diet something you can start today. Shop in a snap--Complete shopping lists to help fill your pantry with all the right food--no more wondering. A meal in 5--Most recipes use just five ingredients so they're fast and easy to prepare, but slow to digest. Insulin resistance and delicious meals don't have to be mutually exclusive. Start reversing insulin resistance and loving the food that you eat with The Insulin Resistance Diet for Beginners.