The origin of life from inanimate matter has been the focus of much research for decades, both experimentally and philosophically. Luisi takes the reader through the consecutive stages from prebiotic chemistry to synthetic biology, uniquely combining both approaches. This book presents a systematic course discussing the successive stages of self-organisation, emergence, self-replication, autopoiesis, synthetic compartments and construction of cellular models, in order to demonstrate the spontaneous increase in complexity from inanimate matter to the first cellular life forms. A chapter is dedicated to each of these steps, using a number of synthetic and biological examples. With end-of-chapter review questions to aid reader comprehension, this book will appeal to graduate students and academics researching the origin of life and related areas such as evolutionary biology, biochemistry, molecular biology, biophysics and natural sciences.

The first novel in ten years from the author of the beloved New York Times bestseller The Particular Sadness Of Lemon Cake, a luminous, poignant tale of a mother, a daughter, mental illness, and the fluctuating barrier between the mind and the world On the night her single mother is taken to a mental hospital after a psychotic episode, eight year-old Francie is staying with her babysitter, waiting to take the train to Los Angeles to go live with her aunt and uncle. There is a lovely lamp next to the couch on which she's sleeping, the shade adorned with butterflies. When she wakes, Francie spies a dead butterfly, exactly matching the ones on the lamp, floating in a glass of water. She drinks it before the babysitter can see. Twenty years later, Francie is compelled to make sense of that moment, and two other incidents -- her discovery of a desiccated beetle from a school paper, and a bouquet of dried roses from some curtains. Her recall is exact -- she is sure these things happened. But despite her certainty, she wrestles with the hold these memories maintain over her, and what they say about her own place in the world. As Francie conjures her past and reduces her engagement with the world to a bare minimum, she begins to question her relationship to reality. The scenes set in Francie's past glow with the intensity of childhood perception, how physical objects can take on an otherworldly power. The question for Francie is, What do these events signify? And does this power survive childhood? Told in the lush, lilting prose that led the San Francisco Chronicle to say Aimee Bender is "a writer who makes you grateful for the very existence of language," The Butterfly Lampshade is a heartfelt and heartbreaking examination of the sometimes overwhelming power of the material world, and a broken love between mother and child.

Why are living things alive? As a theoretical biologist, Robert Rosen saw this as the most fundamental of all questions-and yet it had never been answered satisfactorily by science. The answers to this question would allow humanity to make an enormous leap forward in our understanding of the principles at work in our world. For centuries, it was believed that the only scientific approach to the question "What is life?" must proceed from the Cartesian metaphor (organism as machine). Classical approaches in science, which also borrow heavily from Newtonian mechanics, are based on a process called "reductionism." The thinking was that we can better learn about an intricate, complicated system (like an organism) if we take it apart, study the components, and then reconstruct the system-thereby gaining an understanding of the whole. However, Rosen argues that reductionism does not work in biology and ignores the complexity of organisms. Life Itself, a landmark work, represents the scientific and intellectual journey that led Rosen to question reductionism and develop new scientific approaches to understanding the nature of life. Ultimately, Rosen proposes an answer to the original question about the causal basis of life in organisms. He asserts that renouncing the mechanistic and reductionistic paradigm does not mean abandoning science. Instead, Rosen offers an alternate paradigm for science that takes into account the relational impacts of organization in natural systems and is based on organized matter rather than on particulate matter alone. Central to Rosen's work is the idea of a "complex system," defined as any system that cannot be fully understood by reducing it to its parts. In this sense, complexity refers to the causal impact of organization on the system as a whole. Since both the atom and the organism can be seen to fit that description, Rosen asserts that complex organization is a general feature not just of the biosphere on Earth-but of the universe itself.

Do you spend much of your time struggling against the growing ranks of papers, books, clothes, housewares, mementos, and other possessions that seem to multiply when you're not looking? Do these inanimate objects, the hallmarks of busy modern life, conspire to fill up every inch of your space, no matter how hard you try to get rid of some of them and organize the rest? Do you feel frustrated, thwarted, and powerless in the face of this ever-renewing mountain of stuff? Help is on the way. Cindy Glovinsky, practicing psychotherapist and personal organizer, is uniquely qualified to explain this nagging, even debilitating problem -- and to provide solutions that really work. Writing in a supportive, nonjudmental tone, Glovinsky uses humorous examples, questionnaires, and exercises to shed light on the real reasons why we feel so overwhelmed by papers and possessions and offers individualized suggestions tailored to specific organizing problems. Whether you're drowning in clutter or just looking for a new way to deal with the perennial challenge of organizing and managing material things, this fresh and reassuring approach is sure to help. Making Peace with the Things in Your Life will help you cut down on your clutter and cut down on your stress!

This volume contains papers based on the workshop OC Energy and Information Transfer in Biological Systems: How Physics Could Enrich Biological UnderstandingOCO, held in Italy in 2002. The meeting was a forum aimed at evaluating the potential and outlooks of a modern physics approach to understanding and describing biological processes, especially regarding the transition from the microscopic chemical scenario to the macroscopic functional configurations of living matter. In this frame some leading researchers presented and discussed several basic topics, such as the photon interaction with biological systems also from the viewpoint of photon information processes and of possible applications; the influence of electromagnetic fields on the self-organization of biosystems including the nonlinear mechanism for energy transfer and storage; and the influence of the structure of water on the properties of biological matter."