What do you associate with chemistry? Explosions, innovative materials, plastics, pollution? The public's confused and contradictory conception of chemistry as basic science, industrial producer and polluter contributes to what we present in this book as chemistry's image as an impure science. Historically, chemistry has always been viewed as impure both in terms of its academic status and its role in transforming modern society. While exploring the history of this science we argue for a characteristic philosophical approach that distinguishes chemistry from physics. This reflection leads us to a philosophical stance that we characterise as operational realism. In this new expanded edition we delve deeper into the questions of properties and potentials that are so important for this philosophy that is based on the manipulation of matter rather than the construction of theories./a

In the short, turbulent history of AIDS research and treatment, the boundaries between scientist insiders and lay outsiders have been crisscrossed to a degree never before seen in medical history. Steven Epstein's astute and readable investigation focuses on the critical question of "how certainty is constructed or deconstructed," leading us through the views of medical researchers, activists, policy makers, and others to discover how knowledge about AIDS emerges out of what he calls "credibility struggles." Epstein shows the extent to which AIDS research has been a social and political phenomenon and how the AIDS movement has transformed biomedical research practices through its capacity to garner credibility by novel strategies. Epstein finds that nonscientist AIDS activists have gained enough of a voice in the scientific world to shape NIH–sponsored research to a remarkable extent. Because of the blurring of roles and responsibilities, the production of biomedical knowledge about AIDS does not, he says, follow the pathways common to science; indeed, AIDS research can only be understood as a field that is unusually broad, public, and contested. He concludes by analyzing recent moves to democratize biomedicine, arguing that although AIDS activists have set the stage for new challenges to scientific authority, all social movements that seek to democratize expertise face unusual difficulties. Avoiding polemics and accusations, Epstein provides a benchmark account of the AIDS epidemic to date, one that will be as useful to activists, policy makers, and general readers as to sociologists, physicians, and scientists.

The author lifts the veil of secrecy from scientific research conducted in this country. He presents a shattering indictment of the scientific community from the halls of government to the research centers at major universities and corporations. Documents case after case of influence peddling, doctored research and outright fraud, and reveals how the twin forces of money and status compromise and corrupt the pursuit of scientific truth.

Epstein shows the extent to which AIDS research has been a social and political phenomenon and how the AIDS movement has transformed biomedical research practices through its capacity to garner credibility by novel strategies.

How are the worlds of university biology and commerce blurring? Many university leaders see the amalgamation of academic and commercial cultures as crucial to the future vitality of higher education in the United States. In Impure Cultures, Daniel Lee Kleinman questions the effect of this blending on the character of academic science. Using data he gathered as an ethnographic observer in a plant pathology lab at the University of Wisconsin–Madison, Kleinman examines the infinite and inescapable influence of the commercial world on biology in academia today. Contrary to much of the existing literature and common policy practices, he argues that the direct and explicit relations between university scientists and industrial concerns are not the gravest threat to academic research. Rather, Kleinman points to the less direct, but more deeply-rooted effects of commercial factors on the practice of university biology. He shows that to truly understand research done at universities today, it is first necessary to explore the systematic, pervasive, and indirect effects of the commercial world on contemporary academic practice.

The Critique of Impure Reason: Horizons of Possibility and Meaning comprises a major and important contribution to philosophy. It inaugurates a revolutionary paradigm shift in philosophical thought by providing compelling and long-sought-for solutions to a wide range of philosophical problems. In the process, the massive work fundamentally transforms the way in which the concepts of reference, meaning, and possibility are understood. The book includes a Foreword by the celebrated German philosopher and physicist Carl Friedrich von Weizsäcker. In Kant’s Critique of Pure Reason we find an analysis of the preconditions of experience and of knowledge. In contrast, but yet in parallel, the new Critique focuses upon the ways—unfortunately very widespread and often unselfconsciously habitual—in which many of the concepts that we employ conflict with the very preconditions of meaning and of knowledge. This is a book about the boundaries of frameworks and about the unrecognized conceptual confusions in which we become entangled when we attempt to transgress beyond the limits of the possible and meaningful. We tend either not to recognize or not to accept that we all-too-often attempt to trespass beyond the boundaries of the frameworks that make knowledge possible and the world meaningful. The Critique of Impure Reason proposes a bold, ground-breaking, and startling thesis: that a great many of the major philosophical problems of the past can be solved through the recognition of a viciously deceptive form of thinking to which philosophers as well as non-philosophers commonly fall victim. For the first time, the book advances and justifies the criticism that a substantial number of the questions that have occupied philosophers fall into the category of “impure reason,” violating the very conditions of their possible meaningfulness. The purpose of the study is twofold: first, to enable us to recognize the boundaries of what is referentially forbidden—the limits beyond which reference becomes meaningless—and second, to avoid falling victims to a certain broad class of conceptual confusions that lie at the heart of many major philosophical problems. As a consequence, the boundaries of possible meaning are determined. Bartlett, the author or editor of more than 20 books, is responsible for identifying this widespread and delusion-inducing variety of error, metalogical projection. It is a previously unrecognized and insidious form of erroneous thinking that undermines its own possibility of meaning. It comes about as a result of the pervasive human compulsion to seek to transcend the limits of possible reference and meaning. Based on original research and rigorous analysis combined with extensive scholarship, the Critique of Impure Reason develops a self-validating method that makes it possible to recognize, correct, and eliminate this major and pervasive form of fallacious thinking. In so doing, the book provides at last provable and constructive solutions to a wide range of major philosophical problems. CONTENTS AT A GLANCE Preface Foreword by Carl Friedrich von Weizsäcker Acknowledgments Avant-propos: A philosopher’s rallying call Introduction A note to the reader A note on conventions PART I WHY PHILOSOPHY HAS MADE NO PROGRESS AND HOW IT CAN 1 Philosophical-psychological prelude 2 Putting belief in its place: Its psychology and a needed polemic 3 Turning away from the linguistic turn: From theory of reference to metalogic of reference 4 The stepladder to maximum theoretical generality PART II THE METALOGIC OF REFERENCE A New Approach to Deductive, Transcendental Philosophy 5 Reference, identity, and identification 6 Self-referential argument and the metalogic of reference 7 Possibility theory 8 Presupposition logic, reference, and identification 9 Transcendental argumentation and the metalogic of reference 10 Framework relativity 11 The metalogic of meaning 12 The problem of putative meaning and the logic of meaninglessness 13 Projection 14 Horizons 15 De-projection 16 Self-validation 17 Rationality: Rules of admissibility PART III PHILOSOPHICAL APPLICATIONS OF THE METALOGIC OF REFERENCE Major Problems and Questions of Philosophy and the Philosophy of Science 18 Ontology and the metalogic of reference 19 Discovery or invention in general problem-solving, mathematics, and physics 20 The conceptually unreachable: “The far side” 21 The projections of the external world, things-in-themselves, other minds, realism, and idealism 22 The projections of time, space, and space-time 23 The projections of causality, determinism, and free will 24 Projections of the self and of solipsism 25 Non-relational, agentless reference and referential fields 26 Relativity physics as seen through the lens of the metalogic of reference 27 Quantum theory as seen through the lens of the metalogic of reference 28 Epistemological lessons learned from and applicable to relativity physics and quantum theory PART IV HORIZONS 29 Beyond belief 30 Critique of Impure Reason: Its results in retrospect SUPPLEMENT The Formal Structure of the Metalogic of Reference APPENDIX I: The Concept of Horizon in the Work of Other Philosophers APPENDIX II: Epistemological Intelligence References Index About the author