Addressing clients’ questions and concerns about the role of genetics in mental illness. As we learn more about how our biology and genes can play into the development of a mental health disorder, patients and their families are increasingly seeking answers to tough questions about common risk factors, the likelihood of recurrence, the need for genetic testing, and implications for future generations. A practical, go-to resource for all mental health clinicians, this guide explains just how to address these questions and concerns in a way that’s comprehensible and compassionate. Filled with case studies, sample dialogues, and question-and-answer examples, it is an essential roadmap for practitioners, helping them to demystify a complex issue for their clients and equip them with the accurate, reassuring information they need.

#1 NEW YORK TIMES BESTSELLER • OPRAH’S BOOK CLUB PICK • ONE OF GQ's TOP 50 BOOKS OF LITERARY JOURNALISM IN THE 21st CENTURY • The heartrending story of a midcentury American family with twelve children, six of them diagnosed with schizophrenia, that became science's great hope in the quest to understand the disease. "Reads like a medical detective journey and sheds light on a topic so many of us face: mental illness." —Oprah Winfrey Don and Mimi Galvin seemed to be living the American dream. After World War II, Don's work with the Air Force brought them to Colorado, where their twelve children perfectly spanned the baby boom: the oldest born in 1945, the youngest in 1965. In those years, there was an established script for a family like the Galvins--aspiration, hard work, upward mobility, domestic harmony--and they worked hard to play their parts. But behind the scenes was a different story: psychological breakdown, sudden shocking violence, hidden abuse. By the mid-1970s, six of the ten Galvin boys, one after another, were diagnosed as schizophrenic. How could all this happen to one family? What took place inside the house on Hidden Valley Road was so extraordinary that the Galvins became one of the first families to be studied by the National Institute of Mental Health. Their story offers a shadow history of the science of schizophrenia, from the era of institutionalization, lobotomy, and the schizophrenogenic mother to the search for genetic markers for the disease, always amid profound disagreements about the nature of the illness itself. And unbeknownst to the Galvins, samples of their DNA informed decades of genetic research that continues today, offering paths to treatment, prediction, and even eradication of the disease for future generations. With clarity and compassion, bestselling and award-winning author Robert Kolker uncovers one family's unforgettable legacy of suffering, love, and hope.

As more patients seek information about family risks of psychiatric illness -- an interest likely to increase as gene-identification studies are publicized -- most psychiatrists agree it is their role to discuss these issues but admit they are ill-prepared to do so. Psychiatric Genetics addresses that need as the first book to focus on clinical applications of genetics in psychiatry. It covers issues involved in genetic counseling, the interpretation of familial and genetic information for clinical use, information regarding risks associated with specific psychiatric disorders, risk/benefit considerations related to medication use during pregnancy, and the ethical and social implications of psychiatric genetic knowledge and research -- including the prospects for genetic testing. While other books have been written for the genetics community, this volume is addressed to practitioners: a clinically relevant resource that can help them understand the often bewildering flood of information about genetics -- information difficult to interpret, let alone integrate into practice -- and enable them to respond to patients' requests to predict the risk of recurrence of psychiatric illness or provide information about reproductive and pregnancy-related issues. Experts from psychiatry, genetic epidemiology, molecular genetics, genetic counseling, cognitive psychology, and ethics focus on issues that have received little attention elsewhere yet are of increasing importance to clinicians. Written at a level that assumes no particular expertise in genetics, the book features these immediately applicable benefits: It offers a framework for understanding and critically evaluating the psychiatric genetic research literature, enabling clinicians to better understand the meaning and limitations of genetic discoveries when patients raise questions about media reports. It provides a resource for clinicians who would like more information about the role and content of genetic counseling, outlining a typical counseling session while demonstrating how risks are estimated and discussed. It summarizes genetic aspects of major psychiatric conditions -- from childhood-onset disorders through psychotic, mood, and anxiety disorders to dementia -- as well as neuropsychiatric manifestations of other genetic disorders. It alerts clinicians to risk/benefit considerations related to medication use during pregnancy. It covers the ethical, legal, and social implications of genetic research and counseling, illustrating the dilemmas that arise with new advances. Whether used as a clinical guide, reference, or ancillary text, this book sets the standard for the application of psychiatric genetic knowledge in everyday practice. Psychiatrists, mental health clinicians, and genetic counselors will find it an essential resource for all patient encounters in which genetic issues arise.

A clinician's guide to understanding and responding to the concerns of family members whose loved one suffers from mental illness. Will he always need medication? How should I explain his illness to the children? What should I say to him to be supportive? How should I behave? A diagnosis of a mental illness can change a person forever—indeed, in some cases it can affect the rest of the life course. It can also have a deep and lasting impact on those close to them. Loving and caring, but often frustrated and at times depressed themselves, family members and caregivers have plenty of questions for the psychiatrists, primary care physicians, and other counselors or therapists who are caring for their mentally ill loved one. Here, veteran clinician Igor Galynker equips mental health professionals with everything they need to know to speak with family members compassionately and effectively, conveying treatment information and answering their questions, while also relieving their anxieties. Drawing from years of his own clinical experience, he offers tools for communicating with families about psychiatric symptoms, medications, and alternative treatment options—along with the difficult topics of stigma, denial, and suicide. He covers the ins and outs of schizophrenia, bipolar mood disorder, major depressive disorder, generalized anxiety disorder, panic disorder, obsessive-compulsive disorder, and personality disorders, and outlines the course of each illness, symptoms, and implications for the client’s future and relationships. Finally, he offers advice for managing stress, succeeding at school and work, building strong romantic relationships, and planning families. Clinical case examples throughout showcase Galynker’s narratives in practice, and prepare clinicians for families’ reactions, both good and bad. Whether you are a general practitioner or psychiatric specialist, or concerned loved one, Talking to Families About Mental Illness will enhance your ability to manage a family’s difficult questions and concerns, which can ultimately transform the way they handle the patient’s diagnosis. This book provides all the tools necessary to communicate clearly and effectively, and guide patients and their families on the path to healing.

''Refreshing and informative....describe[s] the new complex research tools, directions and interpretations in a lucid and understandable fashion.'' --- Lancet, North American edition ''Beautifully crafted...The most significant contribution of this book involves its integration of areas that are not typically considered in genetic overviews.'' --- American Scientist, 1998 ''This book does an extraordinary job of making sense out of the many complex and controversial issues surrounding psychiatric genetics...It is worth the price.'' --- Journal of Genetic Counseling, Vol. 6, No. 3, 1997 This collection of essays clearly examines the complex nature of mental illness, focusing on the theory and state of the art of psychiatric genetics. This insightful volume is the first to present the diverse viewpoints of investigators, policy analysts, and psychiatric patients. Contributors explore the roles of genes in mental illness and describe various clinical, ethical, and social implications of psychiatric genetics. Additional discussions include trends in psychiatric genetic research, nature versus nurture in behavioral genetics, basic statistical principles of linkage analysis, and the many social domains relevant to psychiatric genetics.

Psychiatric Genetics is a concise reference that presents the complexities of this dynamic field in a clearly written, easily accessible format, with numerous tables and illustrations. Ten expert contributors offer a fascinating view of psychiatric genetics in a text that is thorough and scholarly yet also succinct and accessible. The introduction summarizes the field's four distinct paradigms -- and their interrelationships -- that help us understand the role of genetic factors in the etiology of psychiatric disorders: basic genetic epidemiology, which demonstrates heritability; advanced genetic epidemiology, which explores the nature and mode of action of these genetic risk factors; gene finding, which enables us to infer the probability that a locus in the genomic region under investigation contributes to psychiatric disorder liability; and molecular genetics, which traces the biological mechanisms by which the DNA variant identified using gene finding methods contributes to the disorder itself. Psychiatric Genetics illustrates the importance of Appreciating the complex field of psychiatric genetics -- Presents the major conceptual and statistical issues in psychiatric genetics, including many of the basic principles of both genetic epidemiology and gene finding, as well as a brief review of DNA itself. Detailing the results for one disorder where substantial progress had been made in gene finding and molecular genetics -- Covers schizophrenia, because of the substantial progress made during the past few years. Presenting results for a more typical and common set of psychiatric disorders where most of our information comes from basic and advanced genetic epidemiology and where we are just beginning to make advances using gene finding -- Discusses anxiety disorders, which illustrate these sets of issues. Covering disorders where major advances have been made using basic and advanced genetic epidemiology -- Details substance use disorders, where the paradigm has shifted from sociological to genetic factors and where, in contrast to the genetics of more traditional psychiatric disorders, researchers must consider the inherent conditionality of drug abuse. Investigating the role of genetics in personality disorders -- Focuses on the development of conduct and antisocial behavior and how to incorporate developmental processes into analyses of the role of genetics. Psychiatric Genetics draws students, educators, and practitioners alike into the exciting world of psychiatric genetics with a lively discussion of its broad trends and of the strengths and limitations of its methods to provide true insight into the etiology of psychiatric and substance use disorders.

A clinician's guide to understanding and responding to the concerns of family members whose loved one suffers from mental illness. Will he always need medication? How should I explain his illness to the children? What should I say to him to be supportive? How should I behave? A diagnosis of a mental illness can change a person forever—indeed, in some cases it can affect the rest of the life course. It can also have a deep and lasting impact on those close to them. Loving and caring, but often frustrated and at times depressed themselves, family members and caregivers have plenty of questions for the psychiatrists, primary care physicians, and other counselors or therapists who are caring for their mentally ill loved one. Here, veteran clinician Igor Galynker equips mental health professionals with everything they need to know to speak with family members compassionately and effectively, conveying treatment information and answering their questions, while also relieving their anxieties. Drawing from years of his own clinical experience, he offers tools for communicating with families about psychiatric symptoms, medications, and alternative treatment options—along with the difficult topics of stigma, denial, and suicide. He covers the ins and outs of schizophrenia, bipolar mood disorder, major depressive disorder, generalized anxiety disorder, panic disorder, obsessive-compulsive disorder, and personality disorders, and outlines the course of each illness, symptoms, and implications for the client’s future and relationships. Finally, he offers advice for managing stress, succeeding at school and work, building strong romantic relationships, and planning families. Clinical case examples throughout showcase Galynker’s narratives in practice, and prepare clinicians for families’ reactions, both good and bad. Whether you are a general practitioner or psychiatric specialist, or concerned loved one, Talking to Families About Mental Illness will enhance your ability to manage a family’s difficult questions and concerns, which can ultimately transform the way they handle the patient’s diagnosis. This book provides all the tools necessary to communicate clearly and effectively, and guide patients and their families on the path to healing.