This volume provides a comprehensive and state-of-the-art review on pediatric hematopoietic stem cell transplantation (HSCT). The book covers such topics as graft versus host disease (GVHD), HSC mobilization, stem cell selection, and HSCT-relevant laboratory assays and techniques. The text is specially formatted so that the scientific basis of HSCT and ethical considerations are integrated into the relevant clinical framework. Each chapter also includes diagrams, illustrations, and tables that summarize key points and concepts that can be used as a quick visual reference for the reader. Written by experts in the field, Hematopoietic Stem Cell Transplantation for the Pediatric Hematologist/Oncologist is a valuable resource on pediatric HSCT suited for pediatric hematologists-oncologists, fellows, advanced practitioners, clinical nurses, and other referring physicians.

This volume provides a concise yet comprehensive overview of patient safety issues and quality improvement for the pediatric hematology/oncology/stem cell transplant practice. The book reviews patient safety in complex healthcare delivery systems, delineates the various safety issues affecting pediatric hematology/oncology patients, and discusses quality improvement methods and improvement science that allow the reader to implement and sustain change in their home institution. The text also explores mechanisms to measure quality and safety outcomes, allowing the provider to implement proven processes shown to minimize harm to patients. Written by experts in the field, Patient Safety and Quality in Pediatric Hematology/Oncology and Stem Cell Transplantation is a valuable resource for healthcare professionals treating pediatric hematology, oncology and stem cell transplant patients.

This book is a comprehensive and up-to-date compendium on all aspects of blood and marrow transplantation in children. After an introductory chapter describing the history of pediatric blood and marrow transplantation, subsequent chapters discuss pediatric-specific aspects of transplantation, including stem cell sources suitable for transplantation, preparative regimens, graft-versus-host disease, complications related to transplantation, and late effects. The role of blood and marrow transplantation in various specific pediatric diseases is then examined, and the closing chapter considers future directions. The authors are all internationally recognized experts and offer a largely evidence-based consensus on etiology, biology, and treatment. This handbook has far-reaching applicability to the clinical diagnosis and management of pediatric diseases that are treatable with blood and marrow transplantation and will prove invaluable to specialists, generalists, and trainees alike.

This unique book is the first on pediatric hematopoietic stem cell transplantation that is especially intended for pharmacists – in recognition of the fact that Pediatric Oncology Pharmacy is an area where more and more specific knowledge is required in daily practice, yet pharmacists who work in pediatric stem cell transplantation do not have a book addressing their specific needs. This pioneering book will likely become the new gold standard for practice, addressing subjects such as stem cells and their differentiation mechanisms; aspects of embryonic and non-embryonic stem cells; stem cell transplantation in pediatrics; stem cell sources and related technical choices; stem cell donors; scheduling transplantations; diseases and chemotherapy protocols that require stem cell transplantation; stem cell homing; engraftment and repopulation of stem cells in bone marrow; autologous stem cell transplantation in pediatrics; allogeneic stem cell transplantation in pediatrics; and indications for autologous and allogeneic pediatric stem cell transplantation. Further, it discusses pediatric graft-versus-host disease and the pharmacist; antibacterial and antifungal prophylaxis; detailed chemotherapy, conditioning and trials for pediatric stem cell transplantation; conditioning granulocyte colony-stimulating factor (G-CSF) in pediatric stem cell transplantation; analyzing prescriptions and programming a pediatric stem cell transplantation; handling chemotherapy and adjuvant drugs for pediatric stem cell transplantation; stem cell transplantation in children up to 1 year old; and clinical pharmacy in pediatric stem cell transplantation. An easy-to-read yet comprehensive guide covering a wide range of topics essential to daily practice, the book offers an invaluable asset for pediatric hemato/ oncology pharmacists, hematologist pharmacists, clinical pharmacists, pediatric pharmacists, pharmaceutical residents and researchers alike.

This volume provides a comprehensive overview of critical care of the pediatric immunocompromised hematology-oncology patient. The text focuses on unique aspects of the pediatric immunocompromised patient that predisposes the child to significant illness, and presents critical care management strategies specific to the patient population. In addition to chapters on oncology, primary immune deficiency, immunocompromised hematology, and hematopoietic cell transplant patients, the book covers the changing landscape of ICU care, pharmacologic considerations, and psychological and social aspects of the critical care of hematology-oncology patients. Written by experts from a range of disciplines, Critical Care of the Pediatric Immunocompromised Hematology/Oncology Patient: An Evidence-Based Guide is a valuable resource for clinicians and practitioners who treat this patient population.

This textbook examines stem cell transplatation in pediatric patients.