Executive Functions in Health and Disease provides a comprehensive review of both healthy and disordered executive function. It discusses what executive functions are, what parts of the brain are involved, what happens when they go awry in cases of dementia, ADHD, psychiatric disorders, traumatic injury, developmental disorders, cutting edge methods for studying executive functions and therapies for treating executive function disorders. It will appeal to neuropsychologists, clinical psychologists, neuroscientists and researchers in cognitive psychology. Encompasses healthy executive functioning as well as dysfunction Identifies prefrontal cortex and other brain areas associated with executive functions Reviews methods and tools used in executive function research Explores executive dysfunction in dementia, ADHD, PTSD, TBI, developmental and psychiatric disorders Discusses executive function research expansion in social and affective neuroscience, neuroeconomics, aging and criminology Includes color neuroimages showing executive function brain activity

Executive Function: Development Across the Life Span presents perspectives from leading researchers and theorists on the development of executive function from infancy to late adulthood and the factors that shape its growth and decline. Executive function is the set of higher-order cognitive processes involved in regulating attention, thoughts, and actions. Relative to other cognitive domains, its development is slow and decline begins early in late adulthood. As such, it is particularly sensitive to variations in environments and experiences, and there is growing evidence that it is susceptible to intervention – important because of its link to a wide range of important life outcomes. The volume is made up of four sections. It begins with an overview of executive function’s typical development across the lifespan, providing a foundation for the remainder of the volume. The second section presents insights into mechanisms of executive function, as provided by a variety of methodological approaches. The third and fourth sections review the current research evidence on specific factors that shape executive function’s development, focusing on normative (e.g., bilingualism, physical activity, cognitive training) and clinically relevant (e.g., substance use, neurodegenerative disease) developmental pathways.

Executive Functions comprise a range of neuropsychological processes related to intentional behavior and cognitive control. There are several theoretical models defining and explaining the concept of Executive Functions. Most of these models consider that the term Executive Functions encompasses cognitive process as working memory, cognitive flexibility, inhibitory control and other complex functions as planning, problem-solving and abstract reasoning. Other models argue that motivational and emotional functions, such as affective decision-making, reside under the concept of Executive Function. Much evidence supports how complex cognitive functions are related to the physiological activity of brain networks, including the frontal cortex and its connections with subcortical structures. Several psychiatric disorders related to impairment in these brain networks (eg., bipolar disorder, schizophrenia, ADHD, obsessive-compulsive disorder, and drug addiction) leading to deficits in Executive Functions. These cognitive deficits affect patients' everyday functioning, worsening the clinical course of the disease. For example, deficits in Executive Functions are related to suicide behavior in bipolar disorder patients. Furthermore, these deficits also relate to obesity, a lack of adherence to treatment and an underperformance in the workplace and educational settings. The understanding of the role of deficits in Executive Functions, including its neurobiological basis, developmental trajectories, and relationship with clinical outcomes, is fundamental to improve clinical management of psychiatric patients. This research topic includes 13 articles with interdisciplinary contributions related to the understanding of the deficits in Executive Functions and its relationship with clinical manifestations in psychiatric disorders.

This volume brings together the leaders in the field of PTSD research to present an up-to-date summary and understanding of this complex disorder. All of our current knowledge and controversies concerning the diagnosis, epidemiology, course, pathophysiology and treatment are described in detail. The evidence for efficacy for each of the different forms of psychotherapy and pharmacotherapy is reviewed. Particular attention is paid to at-risk groups, including minorities, and coverage of PTSD throughout the world is reviewed as well. The authors present state-of-the-art findings in genetics, epigenetics, neurotransmitter function and brain imaging to provide the most current and comprehensive review of this burgeoning field.

The Wisdom Paradox explores the aging of the mind from a unique, positive perspective. In an era of increasing fears about mental deterioration, world-renowned neuropsychologist Elkhonon Goldberg provides startling new evidence that though the brain diminishes in some tasks as it ages, it gains in many ways. Most notably, it increases in what he terms “wisdom”: the ability to draw upon knowledge and experience gained over a lifetime to make quick and effective decisions. Goldberg delves into the machinery of the mind, separating memory into two distinct types: singular (knowledge of a particular incident or fact) and generic (recognition of broader patterns). As the brain ages, the ability to use singular memory declines, but generic memory is unaffected—and its importance grows. As an individual accumulates generic memory, the brain can increasingly rely upon these stored patterns to solve problems effortlessly and instantaneously. Goldberg investigates the neurobiology of wisdom, and draws on historical examples of artists and leaders whose greatest achievements were realized late in life.

The book offers an in-depth, comprehensive, and clinically applicable analysis of executive functioning (EF). Five subdomains of EF are described. For each subdomain, elemental neurocognitive processes, neuroanatomic underpinnings, the role of the subdomain in execution of daily tasks, neuropsychological assessment approaches, and associated clinical syndromes and clinical populations are described.

A brain-based approach to helping kids stay focused and achieve. Poor executive function (EF) in the brain can mean behavioral and attentional problems in school. This book explains to professionals and parents how EF develops in kids, what EF difficulties look like, and what creative and effective interventions can meet their needs. Executive functions involve mental processes such as: Working memory–holding several pieces of information in mind while we try to do something with them–for example, understand and solve a problem or carry out a task. Response inhibition–inhibiting actions that interfere with our intentions or goals. Shifting focus–interrupting an ongoing response in order to direct attention to other aspects of a situation that are important for goal attainment. Cognitive flexibility–generating alternative methods of solving a problem or reaching a goal. Self-monitoring–checking on one's own cognitions and actions to assure that they are in line with one's intentions. Goal Orientation–creating and carrying out a multi-step plan for achieving a goal in a timely fashion, keeping the "big picture" in mind.