This special topic issue addresses the most common endocrine and metabolic complications observed in cancer survivors. It gives an overview to orient endocrinologists to common cancer diagnoses and the therapies most often associated with adverse endocrine outcomes. Additionally, it focuses on the important issues of impaired linear growth, hypogonadism in males and females, disorders of the thyroid gland, diabetes mellitus and the metabolic syndrome, hypothalamic obesity, and disorders of the bone. These state-of-the-art reviews will hopefully assist clinicians in diagnosing and managing the various endocrine disorders experienced by survivors. The goal is to improve quality of life and to reduce morbidity and mortality in a vulnerable population. This publication is a valuable resource for pediatric, adult, and generalist providers caring for childhood cancer and brain tumor survivors.

A state-of-the-art and concise resource presenting the clinical management of pediatric endocrine diseases and disorders, this third edition of the highly regarded textbook covers the most common and challenging conditions seen by practicing endocrinologists and primary care physicians, including growth, hypothalamic, pituitary, adrenal, thyroid, calcium and bone, and reproductive disorders, as well as metabolic syndromes. This expanded third edition includes new topics such as conditions of overgrowth, low bone density and its management, endocrine issues related to sexual identity, mineralocorticoid disorders and endocrine hypertension, and endocrine emergencies. Some existing chapters are expanded to take into account recent advances in the field. Each chapter contains key points, an introductory discussion of the problem, a review of the clinical features that characterize it, the criteria needed to establish a diagnosis, and a comprehensive therapy section delineating the risks and benefits of the best therapeutic options available. New to this edition are concluding sections in each chapter containing relevant case material and multiple choice review questions. Pediatric Endocrinology: A Practical Clinical Guide, Third Edition is a comprehensive resource for all clinicians concerned with the myriad endocrinologic disorders seen in children and adolescents.

More than 80% of patients with cancer will need the services of anesthesiology and perioperative medicine, intensive care medicine, and pain management specialists during their cancer journey for diagnostic, therapeutic, and symptom management needs, as well as for the management of recurrent disease, secondary cancers, and ongoing non-oncologic surgical needs during survivorship. Perioperative Care of the Cancer Patient is today’s most up-to-date, authoritative, comprehensive reference on the acute care of surgical patients with cancer, from a team of international experts in this emerging and dynamic specialty. Covers current clinical practice and perioperative care guidelines during the entire cancer journey for both adult and pediatric patients. Includes a diverse array of topics on cancer care, such as cancer epidemiology, cancer biology, ethics in cancer care delivery, value proposition in cancer care, opportunities and challenges with research programs in perioperative cancer care, application of big data and computational sciences in cancer medicine and care delivery, and the MD Anderson Cancer Center Moon Shots Program®. Discusses newer cancer therapies and their perioperative implications, functional assessment and prehabilitation, enhanced recovery programs in cancer care, challenges with novel cancer therapies in the care of the critically ill cancer patient, chronic and interventional pain management in patients with cancer, and more. An educational resource and clinical reference for surgeons, anesthesia practitioners, hospitalists, internists, pain physicians, intensivists, basic science researchers, and all clinicians involved in the acute care of surgical patients with cancer.

This book analyzes in detail all aspects related to endocrine and metabolic late effects observed in patients treated for cancer, both in childhood and adulthood. The chapters focusing on the possible pathogenic mechanisms of late effects (i.e., premature aging and chronic inflammation) and on bone health in cancer survivors are particularly interesting and innovative. The volume also deals with hypothalamic-pituitary, thyroid and gonadal disorders, including infertility and how to prevent it. Finally, the relationship between metabolic alterations and cardiovascular diseases in cancer survivors is addressed. Thanks to advances in cancer treatment and supportive care, the five-year survival rate of cancer patients is constantly increasing. However, this undisputable success of medicine has a flip side: the late adverse effects of anticancer therapies. Pediatric oncologists were the first to cope with late complications of treatments, but today also adult oncologists and onco-hematologists recognize the relevance of this issue. Even though late effects observed in cancer survivors can affect any organ or system, endocrine and metabolic dysfunctions are the most frequently reported. Endocrine complications rarely influence life expectancy of cancer survivors, but they can significantly impact morbidity and quality of life. Among endocrine adverse effects, severe hypothalamic damage may be considered the most harmful in survivors, leading to morbid obesity, propensity to metabolic syndrome and cardiovascular disease. This book aims to disseminate the knowledge about endocrine and metabolic adverse effects of cancer therapies and about survivorship care. Since the number of cancer survivors is steadily growing in the general population, this publication is intended not only for endocrinologists but also for oncologists, onco-hematologists, internists, pediatric specialists in those areas and general practitioners, with the aim to better counsel and monitor cancer survivors.

The seventh edition of Brook's Clinical Pediatric Endocrinology has been compiled by an experienced editorial team and internationally renowned contributors; it presents basic science and clinical management of endocrine disorders for all involved in the care of children and adolescents. It provides treatments for a variety of hormonal diseases, including diabetes and hypoglycaemia, growth problems, thyroid disease and disorders of puberty, sexual differentiation, calcium metabolism, steroid metabolism and hypopituitarism.

Die 7. Auflage von Brook's Clinical Pediatric Endocrinology wurde von einem erfahrenen Herausgeberteam erarbeitet und enthält Beiträge international erfahrener Experten. Präsentiert werden die wissenschaftlichen Grundlagen und das klinische Management von Hormonstörungen bei Kindern und Jugendlichen. Dieses Fachbuch stellt die Behandlungsoptionen für eine Vielzahl von hormonellen Störungen vor, darunter Diabetes und Hypoglykämie, Wachstumsstörungen, Schilddrüsenerkrankungen, Pubertätsstörungen, sexuelle Differenzierung, Störung des Kalzium- und Steroidstoffwechsels und Hypophyseninsuffizienz.

Practical Pediatric Endocrinology in a Limited Resource Setting provides a guide for managing pediatric endocrine problems in a limited resource setting, together with an outline of the bases for these disorders. The book outlines a plan for coming to a likely diagnosis in situations where resources are constrained, and suggests ways to access more sophisticated technologies for diagnostic confirmation and extension of available tools. Further extending and complementing each chapter is a series of scenarios for use as teaching and learning tools. Together with a clinical question, all chapters include a suggested outline for assessment that assists readers facing similar situations in daily practice. Each scenario works through a typical series of deductive steps used to establish a working diagnosis, while considering both a differential diagnosis and reminding readers of current knowledge around the subject matter. Provides a working knowledge of pediatric endocrinology, from the viewpoint of practical application, for residents and clinicians practicing in settings with scarce material resources Features clinically based chapters, empahsising workable diagnoses and management plans in limited resource situations Includes information on Type 1 diabetes mellitus, given its increasing prevalence worldwide Describes basic research techniques and planning, intended to foster collaboration between colleagues and other centers in clinical or basic research, which can inform clinical practice and drive innovation