The book consists of two parts. The first part consists of 9 chapters which together offer a comprehensive overview of the most important medical and computer-science aspects of clinical guidelines and protocols. The second part of the book consists of chapters that are extended versions of selected papers that were originally submitted to the ECAI-2006 workshop 'AI Techniques in Health Care: Evidence-based Guidelines and Protocols.'

The book consists of two parts. The first part consists of 9 chapters which together offer a comprehensive overview of the most important medical and computer-science aspects of clinical guidelines and protocols. The second part of the book consists of chapters that are extended versions of selected papers that were originally submitted to the ECAI-2006 workshop 'AI Techniques in Health Care: Evidence-based Guidelines and Protocols.'

This book brings together results from different branches of computer science (in particular, artificial intelligence), medical informatics and medicine to examine cutting edge approaches to computer-based guideline modeling, verification and interpretation. Different methods have been developed to support the development, deployment, maintenance and use of evidence-based guidelines, using techniques from artificial intelligence, software engineering, medical informatics and formal methods. Such methods employ different representation formalisms and computational techniques. As the guideline-related research spans a wide range of research communities, a comprehensive integration of the results of these communities was lacking. It is the intention of this book to fill this gap. It is the first book of its kind that partially has the nature of a textbook. The book consists of two parts. The first part consists of nine chapters which together offer a comprehensive overview of the most important medical and computer-science aspects of clinical guidelines and protocols. The second part of the book consists of chapters that are extended versions of selected papers that were originally submitted to the ECAI-2006 workshop ‘AI Techniques in Health Care: Evidence-based Guidelines and Protocols’. These chapters will provide the reader detailed information about actual research in the area by leading researchers.

During the last decade many countries have become increasingly interested in the development and use of evidence-based practice guidelines, recognising that guidelines are key tools to improve the quality and appropriateness of health care. They are considered to be the ideal mediator for bridging the gap between the growing stream of research findings and actual clinical practice. Systematic reviews of guideline evaluations have shown that clinical practice guidelines can be an effective means of both changing the process of healthcare delivery and improving outcomes. A review of 59 guideline evaluation studies found that, in all but 4, statistically significant improvements occurred in clinical practice after implementation [17]. A systematic review of 87 studies on the use of guidelines concluded that 81 studies revealed evidence of improved patient outcomes [12].

Clinical guidelines and Careflow systems have been recently identified as a means to improve and standardize health care services. A number of ICT-based management solutions have been proposed, focussing on several aspects such as specification, process logs verification with respect to specification (compliance), enactment and administration of careflows. In this paper we introduce the GPROVE framework, based on Computational Logic, and focused on the (formal) specification of careflows and on the compliance verification of the process executions w.r.t. the specified models. In particular, we show its application to the Cancer Screening Guideline used by the sanitary organization of the Emilia Romagna region, discussing its formalization in GPROVE and the results of the compliance checking applied to logs of the screening process.

Knowledge is power: In today’s era of knowledge-based economies, constantly changing business environments, severe competition, and globalization, gaining the knowledge edge will greatly empower an organization to stay on the cutting edge. Intelligence Methods and Systems Advancements for Knowledge-Based Business examines state-of-the-art research in decision sciences and business intelligence, and the applications of knowledge-based business with information systems. This comprehensive volume will provide researchers, academics, and business professionals with the research and inspiration they need to strengthen and empower their businesses in today’s world.

Clinical Decision Support and Beyond: Progress and Opportunities in Knowledge-Enhanced Health and Healthcare, now in its third edition, discusses the underpinnings of effective, reliable, and easy-to-use clinical decision support systems at the point of care as a productive way of managing the flood of data, knowledge, and misinformation when providing patient care. Incorporating CDS into electronic health record systems has been underway for decades; however its complexities, costs, and user resistance have lagged its potential. Thus it is of utmost importance to understand the process in detail, to take full advantage of its capabilities. The book expands and updates the content of the previous edition, and discusses topics such as integration of CDS into workflow, context-driven anticipation of needs for CDS, new forms of CDS derived from data analytics, precision medicine, population health, integration of personal monitoring, and patient-facing CDS. In addition, it discusses population health management, public health CDS and CDS to help reduce health disparities. It is a valuable resource for clinicians, practitioners, students and members of medical and biomedical fields who are interested to learn more about the potential of clinical decision support to improve health and wellness and the quality of health care. Presents an overview and details of the current state of the art and usefulness of clinical decision support, and how to utilize these capabilities Explores the technological underpinnings for developing, managing, and sharing knowledge resources and deploying them as CDS or for other uses Discusses the current drivers and opportunities that are expanding the prospects for use of knowledge to enhance health and healthcare