Cellular Effects of Heavy Metals
Title | Cellular Effects of Heavy Metals PDF eBook |
Author | Gaspar Banfalvi |
Publisher | Springer Science & Business Media |
Total Pages | 348 |
Release | 2011-03-02 |
Genre | Medical |
ISBN | 9400704283 |
The term “heavy metals” is used as a group name of toxic metals and metalloids (semimetals) causing contaminations and ecotoxicity. In strict chemical sense the density of heavy metals is higher than 5 g/cm3. From biological point of view as microelements they can be divided into two major groups. a. For their physiological function organisms and cells require essential microelements such as iron, chromium (III), cobalt, copper, manganese, molidenium, zinc. b. The other group of heavy metals is toxic to the health or environment. Of highest concern are the emissions of As, Cd, Co, Cu, Hg, Mn, Ni, Pb, Sn, Tl. The toxicity of heavy metals is well known at organizational level, while less attention has been paid to their cellular effects. This book describes the toxicity of heavy metals on microorganisms, yeast, plant and animal cells. Other chapters of the book deal with their genotoxic, mutagenic and carcinogenic effects. The toxicity of several metals touch upon the aspects of environmental hazard, ecosystems and human health. Among the cellular responses of heavy metals irregularities in cellular mechanisms such as gene expression, protein folding, stress signaling pathways are among the most important ones. The final chapters deal with biosensors and removal of heavy metals. As everybody is eating, drinking and exposed to heavy metals on a daily basis, the spirit of the book will attract a wide audience.
Cellular Effects of Heavy Metals
Title | Cellular Effects of Heavy Metals PDF eBook |
Author | Gaspar Banfalvi |
Publisher | Springer |
Total Pages | 348 |
Release | 2011-03-10 |
Genre | Medical |
ISBN | 9789400704299 |
The term “heavy metals” is used as a group name of toxic metals and metalloids (semimetals) causing contaminations and ecotoxicity. In strict chemical sense the density of heavy metals is higher than 5 g/cm3. From biological point of view as microelements they can be divided into two major groups. a. For their physiological function organisms and cells require essential microelements such as iron, chromium (III), cobalt, copper, manganese, molidenium, zinc. b. The other group of heavy metals is toxic to the health or environment. Of highest concern are the emissions of As, Cd, Co, Cu, Hg, Mn, Ni, Pb, Sn, Tl. The toxicity of heavy metals is well known at organizational level, while less attention has been paid to their cellular effects. This book describes the toxicity of heavy metals on microorganisms, yeast, plant and animal cells. Other chapters of the book deal with their genotoxic, mutagenic and carcinogenic effects. The toxicity of several metals touch upon the aspects of environmental hazard, ecosystems and human health. Among the cellular responses of heavy metals irregularities in cellular mechanisms such as gene expression, protein folding, stress signaling pathways are among the most important ones. The final chapters deal with biosensors and removal of heavy metals. As everybody is eating, drinking and exposed to heavy metals on a daily basis, the spirit of the book will attract a wide audience.
Poisoning in the Modern World
Title | Poisoning in the Modern World PDF eBook |
Author | Ozgur Karcioglu |
Publisher | BoD – Books on Demand |
Total Pages | 130 |
Release | 2019-06-19 |
Genre | Medical |
ISBN | 1838807853 |
Over 400 years ago, Swiss alchemist and physician Paracelsus (1493-1541) cited: "All substances are poisons; there is none that is not a poison. The right dose differentiates a poison from a remedy." This is often condensed to: "The dose makes the poison." So, why are we overtly anxious about intoxications?In fact, poisons became a global problem with the industrial revolution. Pesticides, asbestos, occupational chemicals, air pollution, and heavy metal toxicity maintain high priority worldwide, especially in developing countries. Children between 0 and 5 years old are the most vulnerable to both acute and chronic poisonings, while older adults suffer from the chronic effects of chemicals. This book aims to raise awareness about the challenges of poisons, to help clinicians understand current issues in toxicology.
Heavy Metal Toxicity in Public Health
Title | Heavy Metal Toxicity in Public Health PDF eBook |
Author | John Kanayochukwu Nduka |
Publisher | BoD – Books on Demand |
Total Pages | 162 |
Release | 2020-06-24 |
Genre | Medical |
ISBN | 1838804358 |
It is often said that the “dosage” of any substance determines its remedy or poison effect. Heavy metal sources encompass sewage, pesticides, fertilizers, environmental contamination, occupational exposure/contact through inhalation, ingestion, and skin. Before the advent of technology/the industrial revolution, communicable diseases ravaged the human race but this seems to have given way to non-communicable diseases such as cancers, renal failure, hormonal distortion enzymes, inhibition of fetal growth, and DNA damage causing negative health issues due to heavy metals. This book brings to the fore probably the most recent experimental research/review on heavy metal contamination, remediating techniques, cellular tissue damage, and toxicological and antioxidant effects of heavy metals. It is hoped that its contents will make interesting reading for all.
Trace Metals and Infectious Diseases
Title | Trace Metals and Infectious Diseases PDF eBook |
Author | Jerome O. Nriagu |
Publisher | MIT Press |
Total Pages | 501 |
Release | 2024-06-11 |
Genre | Medical |
ISBN | 0262552485 |
Experts explore the influence of trace metals on the pathogenesis of infectious diseases. Many parts of the world in which common infectious diseases are endemic also have the highest prevalence of trace metal deficiencies or rising rates of trace metal pollution. Infectious diseases can increase human susceptibility to adverse effects of metal exposure (at suboptimal or toxic levels), and metal excess or deficiency can increase the incidence or severity of infectious diseases. The co-clustering of major infectious diseases with trace metal deficiency or toxicity has created a complex web of interactions with serious but poorly understood health repercussions, yet has been largely overlooked in animal and human studies. This book focuses on the distribution, trafficking, fate, and effects of trace metals in biological systems. Its goal is to enhance our understanding of the relationships between homeostatic mechanisms of trace metals and the pathogenesis of infectious diseases. Drawing on expertise from a range of fields, the book offers a comprehensive review of current knowledge on vertebrate metal-withholding mechanisms and the strategies employed by different microbes to avoid starvation (or poisoning). Chapters summarize current, state-of-the-art techniques for investigating pathogen-metal interactions and highlight open question to guide future research. The book makes clear that improving knowledge in this area will be instrumental to the development of novel therapeutic measures against infectious diseases. Contributors M. Leigh Ackland, Vahid Fa Andisi, Angele L. Arrieta, Michael A. Bachman, J. Sabine Becker, Robert E. Black, Julia Bornhorst, Sascha Brunke, Joseph A. Caruso, Jennifer S. Cavet, Anson C. K. Chan, Christopher H. Contag, Heran Darwin, George V. Dedoussis, Rodney R. Dietert, Victor J. DiRita, Carol A. Fierke, Tamara Garcia-Barrera, David P. Giedroc, Peter-Leon Hagedoorn, James A. Imlay, Marek J. Kobylarz, Joseph Lemire, Wenwen Liu, Slade A. Loutet, Wolfgang Maret, Andreas Matusch, Trevor F. Moraes, Michael E. P. Murphy, Maribel Navarro, Jerome O. Nriagu, Ana-Maria Oros-Peusquens, Elisabeth G. Pacyna, Jozef M. Pacyna, Robert D. Perry, John M. Pettifor, Stephanie Pfaffen, Dieter Rehder, Lothar Rink, Anthony B. Schryvers, Ellen K. Silbergeld, Eric P. Skaar, Miguel C. P. Soares, Kyrre Sundseth, Dennis J. Thiele, Richard B. Thompson, Meghan M. Verstraete, Gonzalo Visbal, Fudi Wang, Mian Wang, Thomas J. Webster, Jeffrey N. Weiser, Günter Weiss, Inga Wessels, Bin Ye, Judith T. Zelikoff, Lihong Zhang
Cellular and Molecular Phytotoxicity of Heavy Metals
Title | Cellular and Molecular Phytotoxicity of Heavy Metals PDF eBook |
Author | Mohammad Faisal |
Publisher | Springer Nature |
Total Pages | 451 |
Release | 2020-10-19 |
Genre | Science |
ISBN | 3030459756 |
Plant growth and development is closely dependent on the plant environment, including the wide-spread presence of organic and inorganic xenobiotics and pollutants. Currently, heavy metals are the most common inorganic environmental pollutants and they have pronounced effects and consequences not only for plants, but also for the ecosystem in which the plants form an integral component. It has been suggested that these contaminants accumulate in agricultural crops, thus entering the food chain and posing a significant health risk. Plants growing in polluted sites exhibit altered metabolism, reduced growth, and decreased biomass production. These pollutants adhere to plant roots and exert physical or chemical toxicity and subsequently cell death in plants. Yet, plants have developed various defence mechanisms to counteract the toxicity induced by heavy metals. Only detailed study of the processes and mechanisms would allow researchers and students to understand the interactions, responses, and adaptations of plants to these pollutants; however, there are several unresolved issues and challenges regarding the interaction and biological effects of heavy metals. Therefore, this volume provides relevant, state-of-the-art findings on environmental phytotoxicity and the mechanisms of such interactions at the cellular and molecular levels. This volume consists of chapters on relevant topics contributed by different experts or group of experts so as to make available a comprehensive treatise designed to provide an in-depth analysis of heavy metals phytotoxicity. This book may serve as a reference to scientists, researchers and students in the fields of toxicology, environmental toxicology, phytotoxicology, plant biology, plant physiology, plant biochemistry and plant molecular biology, and especially those interested in heavy metals toxicology.
Biochemical Toxicology
Title | Biochemical Toxicology PDF eBook |
Author | Muharrem Ince |
Publisher | BoD – Books on Demand |
Total Pages | 232 |
Release | 2020-07-29 |
Genre | Medical |
ISBN | 178984696X |
Biochemical Toxicology - Heavy Metals and Nanomaterials provides an overview of biochemical contamination, nanomaterials and toxic metals, and measurement techniques. It explains and clarifies important studies and compares and develops new and groundbreaking measurement techniques in the fields of organic and inorganic pollution and nanoscience. It is highly recommended for professionals and readers interested in the environment and human health.